PNU112455A hydrochloride |
| Catalog No.GC39421 |
A Cdk2 and Cdk5 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21886-12-4
Sample solution is provided at 25 µL, 10mM.
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PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].
[1]. Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.
Review for PNU112455A hydrochloride
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
Review for PNU112455A hydrochloride
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