Home>>Progesterone 3-PEG11-biotin

Progesterone 3-PEG11-biotin

Catalog No.GC44692

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones.

Products are for research use only. Not for human use. We do not sell to patients.

Progesterone 3-PEG11-biotin Chemical Structure

Size Price Stock Qty
500μg
$124.00
In stock
1mg
$235.00
In stock
5mg
$987.00
In stock
10mg Please Inquire Please Inquire

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. The main function of progesterone is to prepare the uterine lining for implantation of a fertilized ovum and to maintain pregnancy. Measurement of serum or plasma progesterone levels are used as an index to monitor ovulation and investigate luteal function. Progesterone 3-PEG11-biotin is an affinity probe that allows progesterone to be detected or immobilized using the biotin ligand. The PEG11 moiety serves to separate the biotin linker from progesterone with a hydrophilic spacer.

Chemical Properties

Cas No. SDF
Canonical SMILES [H][C@]12[C@](NC(N2)=O)([H])CSC1CCCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CO/N=C3CCC(C(CCC4(C)C5CCC4C(C)=O)C5CC6)(C)C6=C\3)=O)=O
Formula C57H97N5O16S M.Wt 1140.5
Solubility Ethanol: 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.8768 mL 4.384 mL 8.7681 mL
5 mM 0.1754 mL 0.8768 mL 1.7536 mL
10 mM 0.0877 mL 0.4384 mL 0.8768 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

Review for Progesterone 3-PEG11-biotin

Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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