Prostaglandin E3 (Synonyms: PGE3) |
| Catalog No.GC40611 |
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 802-31-3
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.[2]
Reference:
[1]. Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31(6), 1159-1164 (1986).
[2]. Kulkarni, P.S., and Srinivasan, B.D. Prostaglandins E3 and D3 lower intraocular pressure. Investigative Ophthalmology & Visual Science 26, 1178-1182 (1985).
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