Home>>Signaling Pathways>> Metabolism>> Reproductive Biology>>Prostaglandin F2α 1,11-lactone

Prostaglandin F2α 1,11-lactone (Synonyms: PGF2α 1,11lactone)

Catalog No.GC41140

PGF2α 1,11-lactone is a lipid-soluble internal ester of PGF2α.

Products are for research use only. Not for human use. We do not sell to patients.

Prostaglandin F2α 1,11-lactone Chemical Structure

Cas No.: 62410-84-8

Size Price Stock Qty
1mg
$121.00
In stock
5mg
$540.00
In stock
10mg
$960.00
In stock

Tel:(909) 407-4943 Email: sales@glpbio.com

Customer Reviews

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

View current batch:

Background

PGF2α 1,11-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone by plasma esterases readily produces free PGF2α in rats and monkeys, but not in humans. PGF2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity compared to PGF2α.

Chemical Properties

Cas No. 62410-84-8 SDF
Synonyms PGF2α 1,11lactone
Canonical SMILES O[C@H]1C[C@@H]2[C@H](/C=C/[C@@H](O)CCCCC)[C@H]1C/C=C\CCCC(O2)=O
Formula C20H32O4 M.Wt 336.5
Solubility DMF: >20 mg/ml (from PGF2a 1,15-lac,DMSO: >10 mg/ml (from PGF2a 1,15-lac,Ethanol: >100 mg/ml (from PGF2a 1,15-la,Ethanol:PBS (30:70): 8 mg/ml,PBS pH 7.2: <50 µ g/ml (from PGF2a 1,15-lac Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.9718 mL 14.8588 mL 29.7177 mL
5 mM 0.5944 mL 2.9718 mL 5.9435 mL
10 mM 0.2972 mL 1.4859 mL 2.9718 mL
  • Molarity Calculator

  • Dilution Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

Review for Prostaglandin F2α 1,11-lactone

Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for Prostaglandin F2α 1,11-lactone

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.