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Pyrotinib Racemate (SHR-1258 Racemate) (Synonyms: (Rac)-SHR-1258)

Catalog No.GC30294

Pyrotinib Racemate (SHR-1258 Racemate) ((Rac)-SHR-1258) is the racemate of Pyrotinib.

Products are for research use only. Not for human use. We do not sell to patients.

Pyrotinib Racemate (SHR-1258 Racemate) Chemical Structure

Cas No.: 1246089-97-3

Size Price Stock Qty
1mg
$175.00
In stock
5mg
$597.00
In stock
10mg
$873.00
In stock
25mg
$1,792.00
In stock
50mg
$2,712.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Pyrotinib Racemate is the racemate of Pyrotinib. Pyrotinib is a potent and selective EGFR/HER2 dual inhibitor.

Chemical Properties

Cas No. 1246089-97-3 SDF
Synonyms (Rac)-SHR-1258
Canonical SMILES O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/C5N(C)CCC5
Formula C32H31ClN6O3 M.Wt 583.08
Solubility DMSO : 1.81 mg/mL (3.10 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.715 mL 8.5752 mL 17.1503 mL
5 mM 0.343 mL 1.715 mL 3.4301 mL
10 mM 0.1715 mL 0.8575 mL 1.715 mL
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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

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Average Rating: 5 ★★★★★ (Based on Reviews and 39 reference(s) in Google Scholar.)

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