R-BC154 |
| Catalog No.GC50326 |
High affinity fluorescent a4 beta 1/a9 beta 1 inhibitor; mobilizes HSCs
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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High affinity fluorescent α4β1/α9β1 inhibitor (Kd values are 12.7 and 38 nM, respectively); fluorescent version of BOP (Cat.No. 6047). Rapidly and preferentially mobilizes HSCs and progenitors in vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm.
Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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