R8-T198wt |
Catalog No.GC13488 |
Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad;
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2305815-72-7
Sample solution is provided at 25 µL, 10mM.
Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad; induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim-1-dependent growth of DU145 cells in vitro and in vivo. Displays no effect on the growth of normal prostate epithelial RPWE-1 cells at concentrations of 10 and 20 μM.
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(Based on Reviews and 30 reference(s) in Google Scholar.)Review for R8-T198wt
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