RA 839 |
| Catalog No.GC50242 |
Nrf2 activator; inhibits Nrf2/Keap1 interaction
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1832713-02-6
Sample solution is provided at 25 µL, 10mM.
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Nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd = 6 μM). Suppresses LPS-induced iNOS and nitric oxide expression in macrophages. Anti-inflammatory.
References:
Winkel et al (2015) Characterization of RA839, a noncovalent small molecule binder to Keap1 and selective activator of Nrf2 signaling. J.Biol.Chem. 290 28446 PMID:26459563
Review for RA 839
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
Review for RA 839
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