(rac)-PF-998425 |
| Catalog No.GC63292 |
(Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1076225-26-7
Sample solution is provided at 25 µL, 10mM.
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(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.
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