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Raclopride Catalog No.GC16769

dopamine D2/D3 receptor antagonist

Size Price Stock Qty
5mg
$46.00
In stock
10mg
$65.00
In stock
25mg
$130.00
In stock
50mg
$222.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Chemical Properties

Cas No. 84225-95-6 SDF
Chemical Name (S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide
Canonical SMILES ClC1=C(C(C(NC[C@H]2N(CC)CCC2)=O)=C(C(Cl)=C1)O)OC
Formula C15H20Cl2N2O3 M.Wt 347.24
Solubility Soluble in DMSO Storage Store at RT
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively[1].

References:
[1]. Seeman P, et al. Dopamine receptor pharmacology. Trends Pharmacol Sci. 1994 Jul;15(7):264-70.