Radafaxine hydrochloride (GW-353162A) (Synonyms: BUPOH, BW 306U, GW 353162A, Radafaxine) |
| Catalog No.GC31060 |
Radafaxine hydrochloride (GW-353162A) (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.
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Cas No.: 106083-71-0
Sample solution is provided at 25 µL, 10mM.
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Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.
[1]. Xu H, et al. Stereoselective analysis of hydroxybupropion and application to drug interaction studies. Chirality. 2007 Mar;19(3):163-70. [2]. Bondarev ML, et al. Behavioral and biochemical investigations of bupropion metabolites. Eur J Pharmacol. 2003 Aug 1;474(1):85-93.
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