RAGE antagonist peptide |
| Catalog No.GC50401 |
RAGE antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1092460-91-7
Sample solution is provided at 25 µL, 10mM.
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Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
Arumugam et al (2012) S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis. Clin.Cancer.Res. 18 4356 PMID:22718861 |Yao et al (2016) The receptor for advanced glycation end products is required for beta -catenin stabilization in a chemical-induced asthma model. Br.J.Pharmacol. 173 2600 PMID:27332707
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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