Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) (Synonyms: GLYX-13 Trifluoroacetate) |
| Catalog No.GC33492 |
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1435786-04-1
Sample solution is provided at 25 µL, 10mM.
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Rapastinel Trifluoroacetate is an NMDA receptor modulator with glycine-site partial agonist properties and currently in a phase II clinical development program as an adjunctive therapy for major depressive disorder.
Rapastinel Trifluoroacetate is an NMDA receptor modulator with glycine-site partial agonist properties and currently in a phase II clinical development program as an adjunctive therapy for major depressive disorder. Mice given Rapastinel Trifluoroacetate (1.0 mg/kg) prior to acute ketamine (30 mg/kg) show clear preference for novel compare to familiar objects (P0.05][2].
[1]. Rajagopal L, et al. GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice. Behav Brain Res. 2016 Feb 15;299:105-10. [2]. Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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