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Home >> Signaling Pathways >> Angiogenesis

Angiogenesis

Products for  Angiogenesis

  1. Cat.No. Product Name Information
  2. GC18025 TCS 2314 integrin very late antigen-4 (VLA-4; α4β1) antagonist TCS 2314 Chemical Structure
  3. GC61316 tcY-NH2 TFA

    (trans-Cinnamoyl)-YPGKF-NH2 TFA

     tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA Chemical Structure
  4. GC61323 Tetrac Tetrac (Tetraiodothyroacetic acid), a derivative of L-thyroxine (T4), is a thyrointegrin receptor antagonist. Tetrac blocks the actions of T4 and 3,5,3'-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3. Tetra has anti-angiogenic and anti-tumor activities. Tetrac Chemical Structure
  5. GC17444 TFLLR-NH2 PAR1 selective agonist TFLLR-NH2 Chemical Structure
  6. GC37770 TFLLR-NH2(TFA) TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. TFLLR-NH2(TFA) Chemical Structure
  7. GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5)

    H2N-Ser-Phe-Leu-Leu-Arg-OH

    Thrombin Receptor Activator for Peptide 5 (TRAP-5) Chemical Structure
  8. GC10140 Thrombin Receptor Agonist Peptide Thrombin Receptor Agonist Peptide is a synthetic thrombin receptor agonist peptide. Thrombin Receptor Agonist Peptide Chemical Structure
  9. GC32945 THS-044 THS-044 binding stabilizes the HIF2α PAS-B folded state, for regulating HIF2 activity in endogenous and clinical settings. THS-044 Chemical Structure
  10. GC45054 Tie2 Inhibitor 7 Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. Tie2 Inhibitor 7 Chemical Structure
  11. GC32228 Tilorone dihydrochloride

    NSC 143969

     An interferon-inducing antiviral agent Tilorone dihydrochloride Chemical Structure
  12. GC33821 Tirabrutinib (ONO-4059)

    GS-4059, ONO-WG-307, Tirabrutinib

     Tirabrutinib (ONO-4059) (ONO-4059) is an orally active Bruton's Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib (ONO-4059) Chemical Structure
  13. GC34097 Tirabrutinib hydrochloride (ONO-4059 (hydrochloride))

    GS-4059, ONO-WG-307

     Tirabrutinib (ONO-4059) hydrochloride is an orally active Bruton's Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib hydrochloride (ONO-4059 (hydrochloride)) Chemical Structure
  14. GC13255 Tirofiban selective platelet GPIIb/IIIa antagonist Tirofiban Chemical Structure
  15. GC11371 Tirofiban hydrochloride monohydrate A GPIIb/IIIa antagonist Tirofiban hydrochloride monohydrate Chemical Structure
  16. GC63229 TL-895 TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1.5 nM and 11.9 nM, respectively. TL-895 Chemical Structure
  17. GC37801 TM6089 TM6089 is a unique Prolyl Hydroxylase (PHD) inhibitor which stimulates HIF activity without iron chelation and induces angiogenesis and exerts organ protection against ischemia. TM6089 Chemical Structure
  18. GC63232 Tolebrutinib

    SAR442168; PRN2246

     Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib Chemical Structure
  19. GC31498 TP0463518

    TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor

     TP0463518 Chemical Structure
  20. GC37818 TR-14035 TR-14035 is a orally active dual α4β7/α4β1 integrin antagonist, with IC50 s of 7 nM and 87 nM for α4β7 and α4β1, respectively. TR-14035 Chemical Structure
  21. GC48195 trans-trismethoxy Resveratrol-d4

    (E)-5-2-(4-hydroxyphenyl)ethenyl-1,3-benzene diol-d4, TMS-d4, trans-3,5,4'-Trimethoxystilbene-d4

     An internal standard for the quantification of trans-trismethoxy resveratrol trans-trismethoxy Resveratrol-d4 Chemical Structure
  22. GC11662 TRAP-6

    PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6

    PAR1 agonist

     TRAP-6 Chemical Structure
  23. GC65529 TRAP-6 amide TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide. TRAP-6 amide Chemical Structure
  24. GC48210 TRX-818 (sodium salt) An anticancer compound TRX-818 (sodium salt) Chemical Structure
  25. GC73855 UBX-382 UBX-382 is an orally available proteolysis-targeting chimeras (PROTACs) that target BTK to inactivate B-cell receptor signaling. UBX-382 Chemical Structure
  26. GC37852 UDM-001651 UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 Chemical Structure
  27. GC16811 Vadadustat

    AKB6548, PG-1016548

     HIF-PH inhibitor Vadadustat Chemical Structure
  28. GC63490 Valategrast

    R-411 free base

     Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast Chemical Structure
  29. GC64212 Valategrast hydrochloride

    R-411

     Valategrast hydrochloride (R-411) is a potent integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast hydrochloride Chemical Structure
  30. GC45769 Vandetanib-d6

    ZD6474-d6

     An internal standard for the quantification of vandetanib Vandetanib-d6 Chemical Structure
  31. GC37889 VCE-004.8

    VCE-?004.8

     VCE-004.8 (VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist. VCE-004.8 Chemical Structure
  32. GC34077 Vecabrutinib (SNS-062) Vecabrutinib (SNS-062) (SNS-062) is a potent, noncovalent BTK and ITK inhibitor, with Kd values of 0.3 nM and 2.2 nM, respectively. Vecabrutinib (SNS-062) shows an IC50 of 24 nM for ITK. Vecabrutinib (SNS-062) Chemical Structure
  33. GC34211 Vedolizumab Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. Vedolizumab Chemical Structure
  34. GC74470 Veltuzumab

    IMMU-106; hA20

     Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody. Veltuzumab Chemical Structure
  35. GC11727 VKGILS-NH2 control peptide for SLIGKV-NH2, PAR1 agonist VKGILS-NH2 Chemical Structure
  36. GC72366 Volociximab Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Volociximab Chemical Structure
  37. GC17545 Vorapaxar PAR-1 antagonist,potent and orally active Vorapaxar Chemical Structure
  38. GC64347 Vorapaxar sulfate Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate Chemical Structure
  39. GC48360 WKYMVm (trifluoroacetate salt)

    Trp-Lys-Tyr-Met-Val-D-Met

     WKYMVm (trifluoroacetate salt) Chemical Structure
  40. GC34075 Zanubrutinib (BGB-3111)

    BGB-3111

     Zanubrutinib (BGB-3111) (BGB-3111) is a selective Bruton tyrosine kinase (Btk) inhibitor. Zanubrutinib (BGB-3111) Chemical Structure
  41. GC37960 Zaurategrast Zaurategrast (CT7758) is a potent and oral-effective α4-integrin inhibitor. Zaurategrast Chemical Structure
  42. GC37961 Zaurategrast ethyl ester Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders. Zaurategrast ethyl ester Chemical Structure
  43. GC37962 Zaurategrast ethyl ester sulfate Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders. Zaurategrast ethyl ester sulfate Chemical Structure
  44. GC37966 ZINC13466751 ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 ?M. ZINC13466751 Chemical Structure

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