PAR1
PAR1 (protease-activated receptor 1) is a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain.
Products for PAR1
- Cat.No. Product Name Information
- GC17368 2-Furoyl-LIGRLO-amide Protease-activated receptor agonist
- GC38731 2-Furoyl-LIGRLO-amide TFA 2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.
- GC14831 AC 264613 PAR2 agonist,potent and selective
- GC15290 AC 55541 PAR2 agonist,potent and selective
- GC63658 Atopaxar Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist.
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GC18152
AZ-3451
A potent, and selective PAR2 antagonist with Kd of 13.5 nM.
- GC65312 AZ8838 AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2.
- GC18717 BMS 986120 A selective PAR4 antagonist
- GC60807 ENMD-1068 hydrochloride Selective protease-activated receptor 2 (PAR2) anatagonist
- GC61501 FSLLRY-NH2 TFA FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor.
- GC36125 GB-110 GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.
- GC38329 GB-110 hydrochloride GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.
- GC65439 GB-88 GB-88 is an oral, selective non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 ?M.
- GC64979 I-191 I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist.
- GC13227 LRGILS-NH2 Protease-activated receptor agonist
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GC11951
PAR 4 (1-6)
PAR4 agonist
- GC62101 PAR-2-IN-1 PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects.
- GA23350 PAR-3 (1-6) amide (human) PAR-3 (1-6) amide (human) is a proteinase-activated receptor (PAR-3) agonist peptide.
- GC33599 PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
- GC15817 PAR-4 Agonist Peptide, amide (AY-NH2) PAR-4 Agonist Peptide, amide(AY-NH2) (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.
- GC38134 Parmodulin 2 Reversible inhibitor of PAR1mediated platelet activation
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GC69663
Parstatin(mouse) TFA
Parstatin (mouse) TFA is a peptide agonist of the PAR-1 thrombin receptor with cell-penetrating properties and an effective inhibitor of angiogenesis.
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GC69768
Protease-Activated Receptor-1, PAR-1 Agonist
Protease-Activated Receptor-1, PAR-1 Agonist is a selective peptide that activates Protease-Activated Receptor-1 (PAR-1), which corresponds to the PAR1 ligand and selectively mimics the action of thrombin through this receptor.
- GC62469 Protease-Activated Receptor-1, PAR-1 Agonist TFA Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor.
- GC61456 Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide.
- GC33429 Protease-Activated Receptor-4 Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
- GC17991 RLLFT-NH2 Protease-activated receptor agonist
- GC61777 RWJ-56110 dihydrochloride RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4.
- GC10291 SCH 79797 dihydrochloride PAR1 receptor antagonist
- GC63540 SCH79797 SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist.
- GC14540 SLIGKV-NH2 SLIGKV-NH2 (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.
- GC17514 SLIGRL-NH2 PAR2 activator
- GC61316 tcY-NH2 TFA tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide.
- GC17444 TFLLR-NH2 PAR1 selective agonist
- GC37770 TFLLR-NH2(TFA) TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM.
- GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5)
- GC10140 Thrombin Receptor Agonist Peptide Thrombin Receptor Agonist Peptide is a synthetic thrombin receptor agonist peptide.
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GC11662
TRAP-6
PAR1 agonist
- GC65529 TRAP-6 amide TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.
- GC37852 UDM-001651 UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM).
- GC11727 VKGILS-NH2 control peptide for SLIGKV-NH2, PAR1 agonist
- GC17545 Vorapaxar PAR-1 antagonist,potent and orally active
- GC64347 Vorapaxar sulfate Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM).