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Other Apoptosis

Products for  Other Apoptosis

  1. Cat.No. Product Name Information
  2. GC19054 Azoramide Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. Azoramide  Chemical Structure
  3. GC35458 Bacopaside II A triterpene glycoside Bacopaside II  Chemical Structure
  4. GN10507 Baohuoside I Baohuoside I  Chemical Structure
  5. GC11572 Bardoxolone methyl A synthetic triterpenoid with potent anticancer and antidiabetic activity Bardoxolone methyl  Chemical Structure
  6. GC17195 Bax inhibitor peptide V5 A Bax inhibitor Bax inhibitor peptide V5  Chemical Structure
  7. GC10345 Bay 11-7085

    NK-κB activation inhibitor

    Bay 11-7085  Chemical Structure
  8. GC13035 Bay 11-7821

    A selective and irreversible NF-κB inhibitor

    Bay 11-7821  Chemical Structure
  9. GC16389 BAY 61-3606 A Syk inhibitor BAY 61-3606  Chemical Structure
  10. GC12136 BAY 61-3606 dihydrochloride BAY 61-3606 dihydrochloride  Chemical Structure
  11. GC16516 BCH BCH (BCH) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. BCH  Chemical Structure
  12. GC10744 Bendamustine HCl Bendamustine HCl (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine HCl activats DNA-damage stress response and apoptosis. Bendamustine HCl has potent alkylating, anticancer and antimetabolite properties. Bendamustine HCl  Chemical Structure
  13. GC14930 Benzbromarone TMEM16A/B calcium-activated chloride channel (CaCC) blocker Benzbromarone  Chemical Structure
  14. GN10520 Benzoylpaeoniflorin Benzoylpaeoniflorin  Chemical Structure
  15. GC38683 Benzyl isothiocyanate Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity. Benzyl isothiocyanate  Chemical Structure
  16. GN10358 Berbamine hydrochloride Berbamine hydrochloride  Chemical Structure
  17. GN10539 Bergenin Bergenin  Chemical Structure
  18. GC10734 Beta-Lapachone Beta-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. Beta-Lapachone  Chemical Structure
  19. GC35504 Beta-Zearalanol Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalanol  Chemical Structure
  20. GN10632 Betulin Betulin  Chemical Structure
  21. GC10480 Betulinic acid A plant triterpenoid similar to bile acids Betulinic acid  Chemical Structure
  22. GC12074 BG45 Novel HDAC3-selective inhibitor BG45  Chemical Structure
  23. GC17828 BI-847325 dual inhibitor of MEK and Aurora kinases BI-847325  Chemical Structure
  24. GC11224 BI6727(Volasertib) BI6727(Volasertib) (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. BI6727(Volasertib) inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. BI6727(Volasertib) induces mitotic arrest and apoptosis. BI6727(Volasertib), a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models. BI6727(Volasertib)  Chemical Structure
  25. GC13636 BIBR 1532 Telomerase inhibitor,novel and selective BIBR 1532  Chemical Structure
  26. GC14233 BIO-acetoxime

    GSK-3α/β inhibitor

    BIO-acetoxime  Chemical Structure
  27. GC12426 Birinapant (TL32711) An antagonist of cIAP1, cIAP2, and XIAP Birinapant (TL32711)  Chemical Structure
  28. GN10037 Bisdemethoxycurcumin Bisdemethoxycurcumin  Chemical Structure
  29. GC35530 BJE6-106 BJE6-106 (B106) is a potent, selective 3rd generation PKCδ inhibitor with an IC50 of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC50=50 μM). BJE6-106  Chemical Structure
  30. GC11931 BKM120 An inhibitor of class I PI3K isoforms BKM120  Chemical Structure
  31. GC12822 BML-210(CAY10433) BML-210(CAY10433) is a novel HDAC inhibitor, and its mechanism of action has not been characterized. BML-210(CAY10433)  Chemical Structure
  32. GC11648 BML-277 Chk2 inhibitor,potent and highly selective BML-277  Chemical Structure
  33. GC13628 BMS-833923 An orally bioavailable Smo inhibitor BMS-833923  Chemical Structure
  34. GC16774 Boc-D-FMK An irreversible pan-caspase inhibitor Boc-D-FMK  Chemical Structure
  35. GC33501 Bornyl acetate An acetate form of borneol Bornyl acetate  Chemical Structure
  36. GC11040 Borrelidin threonyl-tRNA synthetase (ThrRS) inhibitor Borrelidin  Chemical Structure
  37. GC17644 Bortezomib (PS-341) Bortezomib (PS-341), as a dipeptide boronic acid proteasome inhibitor with antitumor activity, can potently inhibiit 20S proteasome with Ki of 0.6 nM by targeting a threonine residue.. Bortezomib (PS-341)  Chemical Structure
  38. GC11632 Brassinolide A plant growth regulator Brassinolide  Chemical Structure
  39. GN10802 Brazilin Brazilin  Chemical Structure
  40. GC35554 Brevilin A A sesquiterpene lactone with anticancer activity Brevilin A  Chemical Structure
  41. GC35555 Britannin Britannin, isolated from Inula aucheriana, is a sesquiterpene lactone. Britannin  Chemical Structure
  42. GC35559 Bruceine D Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D  Chemical Structure
  43. GC38467 BTdCPU BTdCPU is a potent heme-regulated eIF2α kinase (HRI) activator. BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell. BTdCPU  Chemical Structure
  44. GC34511 BTR-1 BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death. BTR-1  Chemical Structure
  45. GC11141 BTZO 1 migration inhibitory factor (MIF) binder BTZO 1  Chemical Structure
  46. GC13671 Busulfan DNA alkylating agent Busulfan  Chemical Structure
  47. GC10944 Butein Protein kinase inhibitor Butein  Chemical Structure
  48. GC16818 BX-912 PDK1 inhibitor,potent and ATP-competitive BX-912  Chemical Structure
  49. GC19095 C-DIM12 C-DIM12 is a synthetic Nurr1 activaor induces Nurr1 and DA gene expression in cell lines and primary neurons. C-DIM12  Chemical Structure
  50. GC12733 C646 C646, a potent and selective p300/CBP histone acetyltransferase inhibitor (Ki 400 nM), has been shown to have pleiotropic activity, including neuroprotective, anti-cancer and anti-epithelial-mesenchymal transition (anti-EMT) effects.. C646  Chemical Structure
  51. GC33218 CA-5f A potent late-stage macroautophagy/autophagy inhibitor CA-5f  Chemical Structure
  52. GC15779 Cabozantinib (XL184, BMS-907351) Cabozantinib (XL184, BMS-907351) is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib (XL184, BMS-907351) displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib (XL184, BMS-907351) shows antiangiogenic activity. Cabozantinib (XL184, BMS-907351) disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis. Cabozantinib (XL184, BMS-907351)  Chemical Structure
  53. GC12531 Cabozantinib malate (XL184) Cabozantinib malate (XL184) (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. Cabozantinib malate (XL184)  Chemical Structure
  54. GC10692 Caffeic Acid Phenethyl Ester NF-κB activation inhibitor Caffeic Acid Phenethyl Ester  Chemical Structure
  55. GC15161 Calcium D-Panthotenate Calcium D-Panthotenate (Vitamin B5 calcium salt), a vitamin, can reduce the patulin content of the apple juice. Calcium D-Panthotenate  Chemical Structure
  56. GC30240 Calcium dobesilate Calcium dobesilate, a vasoprotective, is widely used in chronic venous disease, diabetic retinopathy and the symptoms of haemorrhoidal attack in many countries. Calcium dobesilate  Chemical Structure
  57. GC19086 Calicheamicin Calicheamicin is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin  Chemical Structure
  58. GC10342 Calpeptin A calpain inhibitor Calpeptin  Chemical Structure
  59. GN10667 Calycosin Calycosin  Chemical Structure
  60. GC35598 Camellianin A Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE)-inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population. Camellianin A  Chemical Structure
  61. GC12318 Candesartan Cilexetil Prodrug of the angiotensin II receptor 1 (AT1) antagonist candesartan Candesartan Cilexetil  Chemical Structure
  62. GC15866 Capecitabine DNA, RNA and protein synthesis inhibitor Capecitabine  Chemical Structure
  63. GC17918 Capsazepine A TRPV1 antagonist Capsazepine  Chemical Structure
  64. GC18069 Cardamonin Cardamonin ((E)-Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM. Cardamonin  Chemical Structure
  65. GC15089 Carfilzomib (PR-171) A proteasome inhibitor Carfilzomib (PR-171)  Chemical Structure
  66. GN10733 Carnosic acid Carnosic acid  Chemical Structure
  67. GC35612 Carvacrol Carvacrol is a monoterpenoid phenol isolated from Thymus mongolicus Ronn. Carvacrol  Chemical Structure
  68. GC32841 Catechin ((+)-Catechin) Catechin ((+)-Catechin) ((+)-Catechin ((+)-Catechin)) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Catechin ((+)-Catechin)  Chemical Structure
  69. GN10543 caudatin caudatin  Chemical Structure
  70. GC13648 CC-223 CC-223 (CC-223) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. CC-223 inhibits both mTORC1 and mTORC2. CC-223  Chemical Structure
  71. GC39169 CC-92480 CC-92480 (CC-92480), a cereblon E3 ubiquitin ligase modulating drug (CELMoD), acts as a molecular glue. CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity. CC-92480  Chemical Structure
  72. GC19088 CC122 CC122 (CC 122) is an orally active cereblon modulator. CC122  Chemical Structure
  73. GC12891 CCT007093 PPM1D inhibitor CCT007093  Chemical Structure
  74. GC14566 CCT137690 An inhibitor of Aurora kinases and FLT3 CCT137690  Chemical Structure
  75. GC35636 CDK9-IN-7 CDK9-IN-7 (compound 21e) is a selective, highly potent, and orally active CDK9/cyclin T inhibitor (IC50=11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD=148 nM; CDK6/cyclinD=145 nM). CDK9-IN-7 shows antitumor activity without obvious toxicity. CDK9-IN-7 induces NSCLC cell apoptosis, arrests the cell cycle in the G2 phase, and suppresses the stemness properties of NSCLC. CDK9-IN-7  Chemical Structure
  76. GC19096 CDKI-73 CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). CDKI-73  Chemical Structure
  77. GC15083 Celastrol A triterpenoid antioxidant Celastrol  Chemical Structure
  78. GN10113 Cepharanthine Cepharanthine  Chemical Structure
  79. GC11543 Cesium chloride Cesium chloride  Chemical Structure
  80. GC35668 CG-200745 CG-200745 (CG-200745) is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. CG-200745 inhibits deacetylation of histone H3 and tubulin. CG-200745 induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. CG-200745 enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine and 5-Fluorouracil (5-FU; ). CG-200745 induces apoptosis and has anti-tumour effects. CG-200745  Chemical Structure
  81. GC10666 CGP 57380 MNK1 inhibitor, specific and selective CGP 57380  Chemical Structure
  82. GC43234 Chaetoglobosin A Chaetoglobosin A is a mycotoxic cytochalasin that was first isolated from the marine-derived endophytic fungus C. Chaetoglobosin A  Chemical Structure
  83. GN10463 Chelerythrine Chelerythrine  Chemical Structure
  84. GC13065 Chelerythrine Chloride Potent inhibitor of PKC and Bcl-xL Chelerythrine Chloride  Chemical Structure
  85. GC40878 Chelidonine Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. Chelidonine  Chemical Structure
  86. GC15739 CHIR-124 Chk1 inhibitor,novel and potent CHIR-124  Chemical Structure
  87. GC35682 CHMFL-ABL/KIT-155 CHMFL-ABL/KIT-155 (CHMFL-ABL-KIT-155; compound 34) is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s of 46 nM and 75 nM, respectively), and it also presents significant inhibitory activities to BLK (IC50=81 nM), CSF1R (IC50=227 nM), DDR1 (IC50=116 nM), DDR2 (IC50=325 nM), LCK (IC50=12 nM) and PDGFRβ (IC50=80 nM) kinases. CHMFL-ABL/KIT-155 (CHMFL-ABL-KIT-155) arrests cell cycle progression and induces apoptosis. CHMFL-ABL/KIT-155  Chemical Structure
  88. GC13408 CI994 (Tacedinaline) An inhibitor of HDAC1, -2, and -3 CI994 (Tacedinaline)  Chemical Structure
  89. GC19436 CID-5721353 CID5721353 is an inhibitor of BCL6 with an IC50 value of 212 μM, which corresponds to a Ki of 147 μM. CID-5721353  Chemical Structure
  90. GC32997 Cinchonine ((8R,9S)-Cinchonine) Cinchonine ((8R,9S)-Cinchonine) is a natural compound present in Cinchona bark. Cinchonine ((8R,9S)-Cinchonine) activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine ((8R,9S)-Cinchonine)  Chemical Structure
  91. GN10189 Cinobufagin Cinobufagin  Chemical Structure
  92. GC17491 CITCO

    Constitutive androstane receptor (CAR) agonist

    CITCO  Chemical Structure
  93. GC31186 Citicoline sodium salt Citicoline sodium salt salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects. Citicoline sodium salt  Chemical Structure
  94. GC41514 Citreoviridin Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system. Citreoviridin  Chemical Structure
  95. GC14203 Citric acid

    Commonly used laboratory reagent

    Citric acid  Chemical Structure
  96. GC10509 Cladribine Apoptosis inducer in CLL cells Cladribine  Chemical Structure
  97. GC15219 Clofarabine Antimetabolite,inhibit DNA polymerase and ribonucleotide reductase Clofarabine  Chemical Structure
  98. GC10813 Clofibric Acid PPAR agonist Clofibric Acid  Chemical Structure
  99. GC32587 Clofilium tosylate Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Clofilium tosylate  Chemical Structure
  100. GC10033 Cobimetinib A potent, orally available MEK1 inhibitor Cobimetinib  Chemical Structure
  101. GN10123 Columbianadin Columbianadin  Chemical Structure

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