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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis

Products for  Other Apoptosis

  1. Cat.No. Product Name Information
  2. GC12105 Etidronate Etidronate (Etidronate) is an orally and intravenously active bisphosphonate. Etidronate Chemical Structure
  3. GC15617 Etoposide

    Topo II inhibitor

     Etoposide Chemical Structure
  4. GC10855 Etretinate retinoid receptor agonist Etretinate Chemical Structure
  5. GC16517 Eugenol naturally occuring scent chemical Eugenol Chemical Structure
  6. GC38165 Euphorbia Factor L1 Euphorbia Factor L1 Chemical Structure
  7. GC38392 Euscaphic acid Euscaphic acid, a DNA polymerase inhibitor, is a triterpene from the root of the R. alceaefolius Poir. Euscaphic inhibits calf DNA polymerase α (pol α) and rat DNA polymerase β (pol β) with IC50 values of 61 and 108 μM. Euscaphic acid induces apoptosis. Euscaphic acid Chemical Structure
  8. GC14791 F16 potential antitumor agent F16 Chemical Structure
  9. GC38437 Fangchinoline An alkaloid with diverse biological activities Fangchinoline Chemical Structure
  10. GC14499 Fenoprofen calcium hydrate nonsteroidal, anti-inflammatory antiarthritic agent Fenoprofen calcium hydrate Chemical Structure
  11. GC12940 Fidaxomicin macrocyclic antibiotic Fidaxomicin Chemical Structure
  12. GC36046 Fimasartan Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Fimasartan Chemical Structure
  13. GC41261 Flavokawain B Flavokawain B is a natural chalcone first isolated from extracts of kava roots. Flavokawain B Chemical Structure
  14. GC36050 Flavokawain C Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells. Flavokawain C Chemical Structure
  15. GC16875 FLLL32 STAT3 inhibitor FLLL32 Chemical Structure
  16. GC13210 Flubendazole Autophagy activator Flubendazole Chemical Structure
  17. GC14144 Fludarabine DNA synthsis inhibitor Fludarabine Chemical Structure
  18. GC15134 Fludarabine Phosphate (Fludara) Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. Fludarabine Phosphate (Fludara) Chemical Structure
  19. GC16880 Flurbiprofen Cyclooxygenase inhibitors Flurbiprofen Chemical Structure
  20. GN10527 Formononetin Formononetin Chemical Structure
  21. GC36065 Formosanin C Formosanin C is a diosgenin saponin isolated from Paris formosana Hayata and an immunomodulator with antitumor activity. Formosanin C induces apoptosis. Formosanin C Chemical Structure
  22. GC33029 Forodesine (BCX-1777 freebase) Forodesine (BCX-1777 freebase) (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine (BCX-1777 freebase) is a potent human lymphocyte proliferation inhibitor. Forodesine (BCX-1777 freebase) could induce apoptosis in leukemic cells by increasing the dGTP levels. Forodesine (BCX-1777 freebase) Chemical Structure
  23. GC32708 Forodesine hydrochloride (BCX-1777) Forodesine hydrochloride (BCX-1777) (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride (BCX-1777) is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride (BCX-1777) could induce apoptosis in leukemic cells by increasing the dGTP levels. Forodesine hydrochloride (BCX-1777) Chemical Structure
  24. GC12308 Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium is the Combretastatin A4 prodrug that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis. Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium Chemical Structure
  25. GC25428 Foscenvivint (ICG-001) Foscenvivint (ICG-001) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis. Foscenvivint (ICG-001) Chemical Structure
  26. GC38551 FPA-124 FPA-124 Chemical Structure
  27. GC10647 FR 180204

    ERK inhibitor

     FR 180204 Chemical Structure
  28. GC16310 FTI 277 HCl FTI 277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI 277 HCl Chemical Structure
  29. GC32138 Furazolidone A nitrofuran antiprotozoal and antibacterial agent Furazolidone Chemical Structure
  30. GC12178 G-749 FLT3 inhibitor G-749 Chemical Structure
  31. GC36103 Galanthamine hydrobromide Galanthamine hydrobromide Chemical Structure
  32. GN10388 Gallic acid Gallic acid Chemical Structure
  33. GC17655 Ganetespib (STA-9090) Ganetespib (STA-9090) Chemical Structure
  34. GC36114 Ganoderenic acid D Ganoderenic acid D is a triterpene identified from the effective compounds of Ganoderma lucidum extract (GLE). Ganoderenic acid D inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. Ganoderenic acid D Chemical Structure
  35. GN10109 Ganoderic Acid A Ganoderic Acid A Chemical Structure
  36. GC13474 Garcinol

    Inhibitor of PCAF and p300 histone acetyltransferase (HAT) activity

     Garcinol Chemical Structure
  37. GC36122 Gardenin B Gardenin B is a flavonoid isolated from Baccharis scandens. Gardenin B induces cell death in human leukemia cells involves multiple caspases. Gardenin B Chemical Structure
  38. GC32710 GDC-0077 (RG6114) GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutant versus wild-type PI3Kα. GDC-0077 (RG6114) Chemical Structure
  39. GC14247 GDC-0623 MEK1 inhibitor, potent and ATP-uncompetitive GDC-0623 Chemical Structure
  40. GC11177 GDC-0980 (RG7422) GDC-0980 (RG7422) (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC50s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with aKiof 17 nM for mTOR. GDC-0980 (RG7422) Chemical Structure
  41. GC36130 Gemcitabine elaidate A prodrug form of gemcitabine Gemcitabine elaidate Chemical Structure
  42. GN10076 Geniposidic acid Geniposidic acid Chemical Structure
  43. GC14102 Genistein Genistein is an isoflavone belonging to the flavonoid group of compounds and is found in a number of plants. Genistein Chemical Structure
  44. GC36132 Genistein 8-c-glucoside Genistein 8-c-glucoside (G8CG) is a glucoside. Genistein 8-c-glucoside induces mitochondrial membrane depolarization and induces apoptosis. Genistein 8-c-glucoside Chemical Structure
  45. GC40673 Geranyl Acetate Geranyl acetate is a monoterpene that has been found in C. Geranyl Acetate Chemical Structure
  46. GC19164 GGTI298 Trifluoroacetate

    GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 uM; little effect on Ha-Ras with IC50 of >20 uM.

     GGTI298 Trifluoroacetate Chemical Structure
  47. GN10453 Ginkgolide B Ginkgolide B Chemical Structure
  48. GC38027 Ginkgolide J Ginkgolide J Chemical Structure
  49. GN10148 Ginsenoside F2 Ginsenoside F2 Chemical Structure
  50. GC36137 Ginsenoside F4 Ginsenoside F4 (GF4), ginseng saponinis, isolated from notoginseng or red ginseng. Ginsenoside F4 Chemical Structure
  51. GN10544 Ginsenoside Rg1

    Ginsenoside Rg1 is one of the main active ingredients of ginseng and a steroidal glycoside with various biological activities. Ginsenoside Rg1 reduces brain Aβ levels and reduces NF-κB nuclear translocation.

     Ginsenoside Rg1 Chemical Structure
  52. GN10019 Ginsenoside Rg6 Ginsenoside Rg6 Chemical Structure
  53. GN10686 Ginsenoside Rh2 Ginsenoside Rh2 Chemical Structure
  54. GC32998 Ginsenoside Rh4 Ginsenoside Rh4 Chemical Structure
  55. GN10584 Ginsenoside Rk1 Ginsenoside Rk1 Chemical Structure
  56. GC38606 Glaucocalyxin A Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect. Glaucocalyxin A Chemical Structure
  57. GC17255 Gliotoxin An immunosuppressive mycotoxin with diverse biological effects Gliotoxin Chemical Structure
  58. GC36151 Glucagon-Like Peptide (GLP) II, human Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human Chemical Structure
  59. GN10321 Glycitein Glycitein Chemical Structure
  60. GC34092 Glycochenodeoxycholic acid (Chenodeoxycholylglycine) Glycochenodeoxycholic acid (Chenodeoxycholylglycine) (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) (Chenodeoxycholylglycine) induces hepatocyte apoptosis. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) Chemical Structure
  61. GC43776 Glycochenodeoxycholic Acid (sodium salt)

    Glycochenodeoxycholic acid (GCDCA) is a glycine-conjugated form of the primary bile acid chenodeoxycholic acid.

     Glycochenodeoxycholic Acid (sodium salt) Chemical Structure
  62. GC36167 GMB-475 GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein. GMB-475 Chemical Structure
  63. GC14815 GMX1778 (CHS828) GMX1778 (CHS828) (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. GMX1778 (CHS828) (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity. GMX1778 (CHS828) Chemical Structure
  64. GC36179 Gomisin N Gomisin N, isolated from Schisandra chinensis. Gomisin N Chemical Structure
  65. GC15865 GRI 977143

    An LPA2 receptor agonist

     GRI 977143 Chemical Structure
  66. GC13484 Griseofulvin Microtubule associated inhibitor Griseofulvin Chemical Structure
  67. GC12555 GS-9620 A TLR7 agonist GS-9620 Chemical Structure
  68. GC14987 GSK-3 Inhibitor IX (BIO) GSK-3 Inhibitor IX (BIO) (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively. GSK-3 Inhibitor IX (BIO) Chemical Structure
  69. GC15659 GSK-923295 An inhibitor of CENP-E GSK-923295 Chemical Structure
  70. GC11018 GSK1059615 PI3K and mTOR inhibitor,potent and reversible GSK1059615 Chemical Structure
  71. GC10008 GSK1070916 A potent inhibitor of Aurora B and C kinases GSK1070916 Chemical Structure
  72. GC14063 GSK1324726A BET proteins inhibitor GSK1324726A Chemical Structure
  73. GC19179 GSK2256098 GSK2256098 is a selective FAK kinase inhibitor, which inhibits growth and survival of pancreatic ductal adenocarcinoma cells. GSK2256098 Chemical Structure
  74. GC17450 GSK2606414

    A selective PERK inhibitor

     GSK2606414 Chemical Structure
  75. GC11068 GSK2656157 PERK inhibitor GSK2656157 Chemical Structure
  76. GC32681 GSK2795039 A NOX2 inhibitor GSK2795039 Chemical Structure
  77. GC17658 Guggulsterone Broad spectrum steroid receptor ligand Guggulsterone Chemical Structure
  78. GC14123 GW441756 TrkA inhibitor,potent and selective GW441756 Chemical Structure
  79. GC11685 GW5074 C-Raf inhibitor,potent and selective GW5074 Chemical Structure
  80. GC38088 Hederacolchiside A1 Hederacolchiside A1 Chemical Structure
  81. GN10248 Hesperitin Hesperitin Chemical Structure
  82. GC15178 Hexamethonium Bromide Selective antagonist of neuronal-type nicotinic AChR Hexamethonium Bromide Chemical Structure
  83. GC38099 Higenamine Higenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine Chemical Structure
  84. GC38237 Higenamine hydrochloride Higenamine hydrochloride (Norcoclaurine hydrochloride), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine hydrochloride Chemical Structure
  85. GC36229 Hirsutine Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine Chemical Structure
  86. GC32807 HJC0152 hydrochloride An orally bioavailable inhibitor of STAT3 HJC0152 hydrochloride Chemical Structure
  87. GC17023 HLCL-61 HLCL-61 is a first-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5). HLCL-61 Chemical Structure
  88. GC16208 HO-3867 STAT3 inhibitor, selective HO-3867 Chemical Structure
  89. GC11574 HPOB HDAC6 inhibitor, potent and selective HPOB Chemical Structure
  90. GC16713 HS-173 novel PI3K inhibitor HS-173 Chemical Structure
  91. GC11973 HSP990 (NVP-HSP990) HSP990 (NVP-HSP990) is a potent and selective Hsp90 inhibitor, with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90α, Hsp90β, and Grp94, respectively. HSP990 (NVP-HSP990) Chemical Structure
  92. GC36270 Hydrolyzed Fumonisin B1 Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1. Hydrolyzed Fumonisin B1 Chemical Structure
  93. GC16843 Hydroxyurea DNA synthesis inhibitor Hydroxyurea Chemical Structure
  94. GN10302 Hypericin Hypericin Chemical Structure
  95. GC36283 Hypocrellin B A fungal metabolite Hypocrellin B Chemical Structure
  96. GC19194 IACS-10759

    IACS-10759 (IACS-010759) is an oxidative phosphorylation inhibitor, IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation ( OXPHOS )

     IACS-10759 Chemical Structure
  97. GC36286 IACS-10759 Hydrochloride IACS-10759 Hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-10759 Hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-10759 Hydrochloride has the potential for relapsed/refractory AML and solid tumors research. IACS-10759 Hydrochloride Chemical Structure
  98. GC19197 IB-MECA IB-MECA (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. IB-MECA Chemical Structure
  99. GC13246 Ibandronate sodium Ibandronate sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. Ibandronate sodium Chemical Structure
  100. GC19195 Iberdomide Iberdomide (CC-220) is a cereblon modulator with an IC50 of 60 nM. Iberdomide Chemical Structure
  101. GC17287 Iberin induces the expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase Iberin Chemical Structure

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