Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Targets for Cardiovascular
Products for Cardiovascular
- Cat.No. Product Name Information
- GC52145 Bradykinin (human, mouse, rat, bovine) (acetate)
- GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator
- GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin
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GC19530
Brassicasterol
Brassicasterol is a phytosterol found in canola and rapeseed oils, marine algae, and shellfish
- GC45887 Bufuralol-d9 (hydrochloride) An internal standard for the quantification of bufuralol
- GC42994 Butanoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes.
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GC43062
C2 Ceramide (d14:1/2:0)
C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid.
- GC40708 C2 L-erythro Ceramide (d18:1/2:0) C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.
- GC40709 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
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GP10127
Cadherin Peptide, avian
Role in cell adhesion
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GC43136
Campestanol
Campestanol is a phytosterol found in vegetables, fruits, nuts, and seeds.
- GC49433 Capsiate A capsaicin analog with diverse biological activities
- GC43140 Captopril Disulfide Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril.
- GC45398 Captopril-d3
- GC49564 Carazolol-d7 An internal standard for the quantification of carazolol
- GC41449 Carbazeran Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3.
- GC49197 Carbinoxamine-d6 (maleate) An internal standard for the quantification of carbinoxamine
- GC18837 Carbocyclic Thromboxane A2 CTA2 is a stable analog of TXA2.
- GC47045 Carvedilol-d5 An internal standard for the quantification of carvedilol
- GC52389 Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of caveolin-1
- GC43160 CAY10485 Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
- GC40869 CAY10486 Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
- GC41636 CAY10487 The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall.
- GC43166 CAY10535 TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2).
- GC41381 CAY10562 S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors.
- GC43180 CAY10592 Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism.
- GC18879 CAY10662 17(R),18(S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EpETE), a natural cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid, is known to reduce the contraction rate of spontaneously beating heart cells and to protect neonatal rat cardiomyocytes against arrhythmias induced by β-adrenergic agonists (EC50 = ~ 1-2 nM).
- GC18698 CAY10665 Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA).
- GC47053 CAY10746 A ROCK1 and ROCK2 inhibitor
- GC52006 CB-096 An inhibitor of RAN translation
- GC49706 Cerberin A cardiac glycoside with cytotoxic and cardiac modulatory activities
- GC43233 CG 4305 Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells.
- GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt) A CGRP receptor antagonist
- GC43242 Chloramphenicol Succinate Chloramphenicol succinate is a water-soluble prodrug form of the antibiotic chloramphenicol.
- GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine
- GC43247 Chlorthalidone Impurity G Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects.
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GC40203
Cholesterol-d6
Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.
- GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol
- GC19433 Cholesteryl Heptadecanoate Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.
- GC43263 Cholesteryl Stearate Cholesteryl stearate is a cholesterol ester.
- GC47088 Cilostazol-d4 An internal standard for the quantification of cilostazol
- GC43270 Ciprostene (calcium salt) Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.
- GC52327 Ciraparantag (trifluoroacetate salt) An anticoagulant reversal agent
- GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide
- GC49556 Cl-Necrostatin-1 A RIPK1 inhibitor
- GC47103 Clonidine-d4 (hydrochloride) An internal standard for the quantification of clonidine
- GC43281 Clopidogrel Carboxylic Acid (hydrochloride) Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM).
- GC40632 CMS121 A substituted quinoline with diverse biological activities
- GP10134 coagulation factor II (thrombin) B chain fragment [Homo sapiens]
- GC49096 Cobaltic Protoporphyrin IX (chloride) An inducer of HO-1 activity
- GC47116 Coenzyme Q10-d6 An internal standard for the quantification of CoQ10
- GP10010 COG 133
- GC49266 Compstatin (trifluoroacetate salt) A peptide inhibitor of complement activation
- GC47120 Conivaptan-d4 An internal standard for the quantification of conivaptan
- GC43333 CV-6209 (chloride) CV-6209 (chloride) is a potent antagonist of platelet activating factor (PAF).
- GC49410 CVT-2738 An active metabolite of ranolazine
- GC49716 Cyclo(RGDyK) (trifluoroacetate salt) A cyclic peptide ligand of αVβ3 integrin
- GC49863 Cytarabine 5′-monophosphate An active metabolite of cytarabine
- GC19437 D-NAME (hydrochloride) N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester .
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GC43371
Dabigatran Acyl-β-D-Glucuronide
Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.
- GC49684 Dabigatran-13C-d3 An internal standard for the quantification of dabigatran
- GC49682 Dabigatran-d3 An internal standard for the quantification of dabigatran
- GC47175 Deacetylforskolin A diterpene with diverse biological activities
- GC46126 Debrisoquin (hemisulfate) A post-ganglionic sympathetic blocker
- GC40230 Deferasirox-d4 Deferasirox-d4 is intended for use as an internal standard for the quantification of deferasirox by GC- or LC-MS.
- GC43399 Dehydro Amlodipine (fumarate) Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.
- GC49131 Dehydro Warfarin A metabolite of (±)-warfarin
- GC49338 Deltorphin II (trifluoroacetate salt) A peptide agonist of δ2-opioid receptors
- GC52051 Desglymidodrine Desglymidodrine (ST 1059), the active metabolite of Midodrine, is a selective α1-adrenoceptor agonist.
- GC49866 Desmethyl Carvedilol An active metabolite of carvedilol
- GC49409 Desmethyl Ranolazine A metabolite of ranolazine
- GC49459 Desmopressin (trifluoroacetate salt) A vasopressin receptor agonist
- GC43437 Diallyl Disulfide Diallyl disulfide (DADS) is an organosulfur compound derived from allicin, a natural compound found in garlic and related plants.
- GC46131 Diazoxide-d3 An internal standard for the quantification of diazoxide
- GC41485 Digitoxigenin Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D.
- GC49842 Digoxigenin Bisdigitoxoside A Na+/K+-ATPase inhibitor
- GC18455 Digoxigenin Monodigitoxoside Digoxigenin monodigitoxoside is a Na+/K+-ATPase inhibitor and cardiac glycoside metabolite of digoxin .
- GC47223 Digoxin-d3 An internal standard for the quantification of digoxin
- GC49325 Dihydroxyacetone Phosphate (magnesium salt hydrate) A glycerolipid precursor
- GC40629 Dimethoxycurcumin Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells.
- GC49016 Dimethyl 2-ketoglutarate An esterified form of α-ketoglutarate
- GC49376 DL-Aspartic Acid-d3 An internal standard for the quantification of aspartic acid
- GC43492 DL-Propargyl Glycine (hydrochloride) Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator.
- GC45439 Docosahexaenoic Acid-d5 MaxSpec• Standard Docosahexaenoic Acid-d5 MaxSpec• Standard (DHA-d5) is the deuterium labeled Docosahexaenoic Acid.
- GC52052 Dofetilide N-oxide
- GC49497 Dopamine-d4 (hydrochloride) An internal standard for the quantification of dopamine
- GC49045 Dopastin A bacterial metabolite and an inhibitor of dopamine β-hydroxylase
- GC47268 Doxazosin-d8 (hydrochloride) An internal standard for the quantification of doxazosin
- GC43569 DPPP DPPP (DPPP) is a fluoregenic peroxide reactive probe.
- GC47272 Dronedarone-d6 (hydrochloride) An internal standard for the quantification of dronedarone
- GC47280 Edoxaban-d6 An internal standard for the quantification of edoxaban
- GC45444 Eicosapentaenoic Acid-d5 MaxSpec• Standard
- GC52221 Eleclazine An inhibitor of the cardiac late INa
- GC46137 Emestrin A mycotoxin
- GP10065 Endomorphin-1
- GP10117 Endostatin (84-114)-NH2 (JKC367)
- GP10062 Endothelin-1 (1-15), amide, human
- GC43608 Endothelin-3 (human, rat) (trifluoroacetate salt) Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively).
- GC40590 ent-8-iso-15(S)-Prostaglandin F2α Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.
- GC52193 Eptifibatide Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity.