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Home >> Signaling Pathways >> Cardiovascular >> Atherosclerosis

Atherosclerosis

Products for  Atherosclerosis

  1. Cat.No. Product Name Information
  2. GC48283 α-Linolenic Acid-d14 An internal standard for the quantification of αLinolenic acid α-Linolenic Acid-d14 Chemical Structure
  3. GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  4. GC41649 (±)13-HODE cholesteryl ester (±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)13-HODE cholesteryl ester Chemical Structure
  5. GC41666 (±)9-HODE cholesteryl ester (±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)9-HODE cholesteryl ester Chemical Structure
  6. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  7. GC46496 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC Chemical Structure
  8. GC41893 13(R)-HODE cholesteryl ester 13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(R)-HODE cholesteryl ester Chemical Structure
  9. GC41895 13(S)-HODE cholesteryl ester 13(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(S)-HODE cholesteryl ester Chemical Structure
  10. GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. 13(S)-HOTrE Chemical Structure
  11. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  12. GC41614 24-dehydro Cholesterol 24-dehydro Cholesterol is a molecule similar to cholesterol. 24-dehydro Cholesterol Chemical Structure
  13. GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  14. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  15. GC42411 4-hydroxy Nonenal Alkyne

    4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

     4-hydroxy Nonenal Alkyne Chemical Structure
  16. GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol Chemical Structure
  17. GC45357 5-Chlorouracil   5-Chlorouracil Chemical Structure
  18. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  19. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  20. GC46241 7-keto Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

     7-keto Cholesterol-d7 Chemical Structure
  21. GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(R)-HODE cholesteryl ester Chemical Structure
  22. GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. 9(S)-HODE Chemical Structure
  23. GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(S)-HODE cholesteryl ester Chemical Structure
  24. GC49784 AZD 2716 An sPLA2 inhibitor AZD 2716 Chemical Structure
  25. GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. Azelaoyl PAF Chemical Structure
  26. GC46912 Beauveriolide III

    A cyclodepsipeptide inhibitor of lipid droplet formation

     Beauveriolide III Chemical Structure
  27. GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt) Chemical Structure
  28. GC42994 Butanoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes. Butanoyl PAF Chemical Structure
  29. GC43136 Campestanol

    Campestanol is a phytosterol found in vegetables, fruits, nuts, and seeds.

     Campestanol Chemical Structure
  30. GC43160 CAY10485 Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  31. GC41636 CAY10487 The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 Chemical Structure
  32. GC40203 Cholesterol-d6

    Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.

     Cholesterol-d6 Chemical Structure
  33. GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  34. GC19433 Cholesteryl Heptadecanoate Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. Cholesteryl Heptadecanoate Chemical Structure
  35. GC43263 Cholesteryl Stearate Cholesteryl stearate is a cholesterol ester. Cholesteryl Stearate Chemical Structure
  36. GC45439 Docosahexaenoic Acid-d5 MaxSpec• Standard Docosahexaenoic Acid-d5 MaxSpec• Standard (DHA-d5) is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid-d5 MaxSpec• Standard Chemical Structure
  37. GC52193 Eptifibatide Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity. Eptifibatide Chemical Structure
  38. GC33760 ETC-1002 (ESP-55016) ETC-1002 (ESP-55016) (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. ETC-1002 (ESP-55016) Chemical Structure
  39. GC47397 Gemfibrozil-d6 An internal standard for the quantification of gemfibrozil Gemfibrozil-d6 Chemical Structure
  40. GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide Gliclazide-d4 Chemical Structure
  41. GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. Graphislactone A Chemical Structure
  42. GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. HA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator. HA-1077 (hydrochloride) Chemical Structure
  43. GC45469 Hexacosanoic Acid-d4   Hexacosanoic Acid-d4 Chemical Structure
  44. GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  45. GC43997 KDdiA-PC Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KDdiA-PC Chemical Structure
  46. GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KOdiA-PC Chemical Structure
  47. GC52497 Lactosylceramide (porcine RBC) A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  48. GC40142 Lactosylceramides (bovine buttermilk) Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid. Lactosylceramides (bovine buttermilk) Chemical Structure
  49. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  50. GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. Lutein Chemical Structure
  51. GC18241 Lysophosphatidylcholines

    Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.

     Lysophosphatidylcholines Chemical Structure
  52. GC49486 Meglutol-d3 An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  53. GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. Methylcarbamyl PAF C-16 Chemical Structure
  54. GC40624 MMP-3 Inhibitor VIII Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  55. GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  56. GC20172 N-Isopropylphthalimide N-Isopropylphthalimide Chemical Structure
  57. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  58. GC44573 PAz-PC Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. PAz-PC Chemical Structure
  59. GC44616 PGPC

    PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.

     PGPC Chemical Structure
  60. GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  61. GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  62. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  63. GC44669 POV-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. POV-PC Chemical Structure
  64. GC49107 Rosuvastatin lactone The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  65. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  66. GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  67. GC45057 TIQ-A Poly(ADP-ribose) polymerase 1 (PARP1) is a critical DNA repair enzyme involved in DNA single-strand break repair via the base excision repair pathway. TIQ-A Chemical Structure
  68. GC48206 Trimethylamine-d9 N-oxide An internal standard for the quantification of trimethylamine N-oxide Trimethylamine-d9 N-oxide Chemical Structure

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