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Home >> Signaling Pathways >> Cardiovascular >> Cholesterol Metabolism

Cholesterol Metabolism

Products for  Cholesterol Metabolism

  1. Cat.No. Product Name Information
  2. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  3. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  4. GC40457 19(R)-HETE

    19(R)-Hydroxyeicosatetraenoic Acid

     19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. 19(R)-HETE Chemical Structure
  5. GC40417 19-hydroxy Cholesterol 19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. 19-hydroxy Cholesterol Chemical Structure
  6. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

     An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  7. GC41614 24-dehydro Cholesterol

    Desmosterol

     24-dehydro Cholesterol is a molecule similar to cholesterol. 24-dehydro Cholesterol Chemical Structure
  8. GC46243 24-dehydro Cholesterol-d6

    Desmosterol-d6

     An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  9. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  10. GC48449 28-(Poc-amino)betulin 28-(Poc-amino)betulin Chemical Structure
  11. GC62033 3α-Hydroxy pravastatin sodium

    3α-Isopravastatin, R-416

     3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. 3α-Hydroxy pravastatin sodium Chemical Structure
  12. GC40799 3-hydroxy-3-Methylglutaric anhydride

    Dicrotalic anhydride, HMG anhydride

     The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride Chemical Structure
  13. GC42405 4-hydroxy Atorvastatin (calcium salt)

    p-hydroxy Atorvastatin, para-hydroxy Atorvastatin

     4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. 4-hydroxy Atorvastatin (calcium salt) Chemical Structure
  14. GC18425 4-hydroxy Atorvastatin lactone

    p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

     4-hydroxy Atorvastatin lactone Chemical Structure
  15. GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α

    6,15diketo13,14dihydro PGF1α

     6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. 6,15-diketo-13,14-dihydro Prostaglandin F1α Chemical Structure
  16. GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor Atorvastatin (calcium salt hydrate) Chemical Structure
  17. GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone Atorvastatin lactone-d5 Chemical Structure
  18. GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin Atorvastatin-d5 (calcium salt) Chemical Structure
  19. GC46911 Beauveriolide I A cyclodepsipeptide inhibitor of lipid droplet formation Beauveriolide I Chemical Structure
  20. GC46912 Beauveriolide III

    A cyclodepsipeptide inhibitor of lipid droplet formation

     Beauveriolide III Chemical Structure
  21. GC45390 Benazepril Acyl-β-D-Glucuronide

    Benazapril Glucuronide

       Benazepril Acyl-β-D-Glucuronide Chemical Structure
  22. GC19530 Brassicasterol

    Brassicasterol is a phytosterol found in canola and rapeseed oils, marine algae, and shellfish

     Brassicasterol Chemical Structure
  23. GC43160 CAY10485

    3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide

     Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  24. GC40869 CAY10486

    4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide

     Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 Chemical Structure
  25. GC47085 Cholesterol-d7

    Provitamin D-d7

     An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  26. GC90700 Dendrogenin A

    A selective LXR modulator and ChEH inhibitor

     Dendrogenin A Chemical Structure
  27. GC47367 Fluvastatin (sodium salt hydrate) An HMG-CoA reductase inhibitor Fluvastatin (sodium salt hydrate) Chemical Structure
  28. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM Chemical Structure
  29. GC43745 Geranyl Pyrophosphate (triammonium salt)

    GDP, Geranyl Diphosphate, GPP

     Geranyl Pyrophosphate (triammonium salt) is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl Pyrophosphate (triammonium salt) Chemical Structure
  30. GC45801 Hesperetin-13C-d3 A neuropeptide with diverse biological activities Hesperetin-13C-d3 Chemical Structure
  31. GC43883 Hymeglusin

    Antibiotic 1233A

    Hymeglusin is a fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme.

     Hymeglusin Chemical Structure
  32. GC49486 Meglutol-d3

    Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3

     An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  33. GC48418 N-(2-Poc-ethyl)betulin amide N-(2-Poc-ethyl)betulin amide Chemical Structure
  34. GC47756 N-desmethyl Rosuvastatin (sodium salt hydrate) An active metabolite of rosuvastatin N-desmethyl Rosuvastatin (sodium salt hydrate) Chemical Structure
  35. GC44497 Oleic Acid-2,6-diisopropylanilide AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic Acid-2,6-diisopropylanilide Chemical Structure
  36. GC44590 Pellitorine An amide alkaloid with diverse biological activities Pellitorine Chemical Structure
  37. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  38. GC40220 Pravastatin-d3 (sodium salt) Pravastatin-d3 is intended for use as an internal standard for the quantification of pravastatin by GC- or LC-MS. Pravastatin-d3 (sodium salt) Chemical Structure
  39. GC49107 Rosuvastatin lactone

    (+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL

     The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  40. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  41. GC49333 SH-42 An inhibitor of DHCR24 SH-42 Chemical Structure
  42. GC50196 Simvastatin - d6

    SVA-d6

     Deuterated simvastatin Simvastatin - d6 Chemical Structure
  43. GC45017 Terpendole C Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. Terpendole C Chemical Structure
  44. GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues. TMP-153 Chemical Structure
  45. GC45090 Triparanol

    MER-29, NSC 65345

     Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. Triparanol Chemical Structure

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