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Home >> Signaling Pathways >> Cardiovascular >> Hypertension

Hypertension

Products for  Hypertension

  1. Cat.No. Product Name Information
  2. GC45200 α-CGRP (rat) (trifluoroacetate salt)

    Calcitonin Gene-Related Peptide-1 (rat), α-Calcitonin Gene-Related Peptide (rat), CGRP-1 (rat)

     α-Calcitonin gene-related peptide (α-CGRP) is a neuropeptide with roles in vasodilation, cardiovascular regulation, and inflammation. α-CGRP (rat) (trifluoroacetate salt) Chemical Structure
  3. GC48283 α-Linolenic Acid-d14

    ALAd14

     An internal standard for the quantification of αLinolenic acid α-Linolenic Acid-d14 Chemical Structure
  4. GC40105 βARK1 Inhibitor βARK1 Inhibitor (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor. βARK1 Inhibitor Chemical Structure
  5. GC52404 γ-Glu-Phe (trifluoroacetate salt)

    γ-Glutamylphenylalanine

     A dipeptide with metabolism-altering activity γ-Glu-Phe (trifluoroacetate salt) Chemical Structure
  6. GC41661 (±)-4-hydroxy Propranolol β-D-Glucuronide (±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol. (±)-4-hydroxy Propranolol β-D-Glucuronide Chemical Structure
  7. GC46273 (±)-Atenolol-d7

    (R,S)-Atenolol-d7, Duraatenol, ICI 66082

     An internal standard for the quantification of (±)-atenolol (±)-Atenolol-d7 Chemical Structure
  8. GC46289 (±)-Felodipine-d5 An internal standard for the quantification of (±)-felodipine (±)-Felodipine-d5 Chemical Structure
  9. GC46304 (±)-Nebivolol-d4 (hydrochloride) A neuropeptide with diverse biological activities (±)-Nebivolol-d4 (hydrochloride) Chemical Structure
  10. GC46307 (±)-Propranolol-d7 An internal standard for the quantification of propranolol (±)-Propranolol-d7 Chemical Structure
  11. GC46312 (±)-Verapamil-d3 (hydrochloride)

    (±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride

     A neuropeptide with diverse biological activities (±)-Verapamil-d3 (hydrochloride) Chemical Structure
  12. GC40268 (±)14(15)-DiHET

    (±)14,15DiHETrE

     Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)14(15)-DiHET Chemical Structure
  13. GC40434 (±)16-HETE

    (±)16-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE Chemical Structure
  14. GC40437 (±)5(6)-DiHET lactone

    (±)5,6DiHETrE lactone

     5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. (±)5(6)-DiHET lactone Chemical Structure
  15. GC41722 (R,S)-Carvedilol Glucuronide (R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R,S)-Carvedilol Glucuronide Chemical Structure
  16. GC18634 11-deoxy Prostaglandin E1

    11deoxy PGE1

     11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. 11-deoxy Prostaglandin E1 Chemical Structure
  17. GC41401 11-deoxy Prostaglandin F1α

    11deoxy PGF1α

     11-deoxy PGF1α is a synthetic analog of PGF1α. 11-deoxy Prostaglandin F1α Chemical Structure
  18. GC41402 11-deoxy Prostaglandin F1β

    9β,11deoxy PGF1α, 11deoxy PGF1β

     11-deoxy PGF1β is a synthetic analog of PGF1β. 11-deoxy Prostaglandin F1β Chemical Structure
  19. GC46425 13,14-dihydro-15-keto Prostaglandin E1-d4

    13,14dh15k PGE1d4

     A neuropeptide with diverse biological activities 13,14-dihydro-15-keto Prostaglandin E1-d4 Chemical Structure
  20. GC41935 15-keto Treprostinil (sodium salt) 15-keto Treprostinil is an impurity found in treprostinil, which is a stable analog of prostaglandin I2 with a longer plasma half-life. 15-keto Treprostinil (sodium salt) Chemical Structure
  21. GC41159 16,16-dimethyl Prostaglandin D2

    16,16dimethyl PGD2

     16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. 16,16-dimethyl Prostaglandin D2 Chemical Structure
  22. GC18635 18-hydroxy-11-deoxy Corticosterone

    18-Hydroxydeoxycorticosterone, 18-OH-DOC

     18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. 18-hydroxy-11-deoxy Corticosterone Chemical Structure
  23. GC52048 3-hydroxy-4-Methoxyphenethylamine (hydrochloride)

    4-O-methyl Dopamine, p-methoxy Dopamine, para-methoxy Dopamine, 4-methoxy-3-Hydroxyphenethylamine

     3-hydroxy-4-Methoxyphenethylamine (hydrochloride) is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase. 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) Chemical Structure
  24. GC42409 4-hydroxy Nebivolol (hydrochloride) 4-hydroxy Nebivolol is a major metabolite of nebivolol. 4-hydroxy Nebivolol (hydrochloride) Chemical Structure
  25. GC42498 5-chloro Hydrochlorothiazide 5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms. 5-chloro Hydrochlorothiazide Chemical Structure
  26. GC41483 5-hydroxy Propranolol 5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist. 5-hydroxy Propranolol Chemical Structure
  27. GC42563 5-methyl-2-HOBA (hydrochloride)

    5-Me-2-HOBA, 5-methyl-2Hydroxybenzylamine

     5-methyl-2-HOBA is an isoketal scavenger. 5-methyl-2-HOBA (hydrochloride) Chemical Structure
  28. GC40338 9-deoxy-9-methylene Prostaglandin E2

    9deoxy9methylene PGE2

     9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene Prostaglandin E2 Chemical Structure
  29. GC48486 AAA A GPR75 antagonist AAA Chemical Structure
  30. GC49406 ACT-373898 A metabolite of macitentan ACT-373898 Chemical Structure
  31. GC42738 Adrenomedullin (13-52) (human) (trifluoroacetate salt) Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52). Adrenomedullin (13-52) (human) (trifluoroacetate salt) Chemical Structure
  32. GC46820 AHU377-d4

    Sacubitril-d4

     AHU377-d4 (AHU-377-d4) is the deuterium labeled Sacubitril. AHU377-d4 Chemical Structure
  33. GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities Alytesin (trifluoroacetate salt) Chemical Structure
  34. GC49638 Ambrisentan-d3 An internal standard for the quantification of ambrisentan Ambrisentan-d3 Chemical Structure
  35. GC46841 Amiloride (hydrochloride) (hydrate)

    MK-870

     A neuropeptide with diverse biological activities Amiloride (hydrochloride) (hydrate) Chemical Structure
  36. GC46845 Amlodipine-d4 (maleate) An internal standard for the quantification of amlodipine Amlodipine-d4 (maleate) Chemical Structure
  37. GC52415 Angiotensin A (trifluoroacetate salt)

    Ala-Arg-Val-Tyr-Ile-His-Pro-Phe, DesAsp1-Ala1-Ang II

     An AT1 and AT2 receptor agonist and active metabolite of angiotensin II Angiotensin A (trifluoroacetate salt) Chemical Structure
  38. GC48997 Argipressin (acetate)

    AVP, Arg8-Vasopressin

     A peptide hormone with vasoconstrictive and antidiuretic activities Argipressin (acetate) Chemical Structure
  39. GC39554 AT2 receptor agonist C21

    Compound 21

     An AT2 receptor agonist AT2 receptor agonist C21 Chemical Structure
  40. GC42871 Atrial Natriuretic Peptide (1-28) (rat) (trifluoroacetate salt)

    ANF, ANP, Atrial Natriuretic Factor, α-Atriopeptin (rat)

     Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. Atrial Natriuretic Peptide (1-28) (rat) (trifluoroacetate salt) Chemical Structure
  41. GC42872 Atrial Natriuretic Peptide (3-28) (human) (trifluoroacetate salt)

    ANP (3-28) (human)

     Atrial natriuretic peptide (ANP) (3-28) is a synthetic and truncated form of ANP, which is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. Atrial Natriuretic Peptide (3-28) (human) (trifluoroacetate salt) Chemical Structure
  42. GC45390 Benazepril Acyl-β-D-Glucuronide

    Benazapril Glucuronide

       Benazepril Acyl-β-D-Glucuronide Chemical Structure
  43. GC42913 Benazeprilat

    CGS 14831

    Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.

     Benazeprilat Chemical Structure
  44. GC42924 Beraprost (sodium salt)

    ML 1129, Procyclin, TRK 100

     Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt) Chemical Structure
  45. GC42966 Bopindolol (malonate)

    (±)-Bopindolol (malonate)

     Bopindolol is a non-selective β-adrenergic receptor antagonist. Bopindolol (malonate) Chemical Structure
  46. GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator Bradykinin (trifluoroacetate salt) Chemical Structure
  47. GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt)

    Arg-Pro-Pro-Gly-Phe, BK1-5, RPPGF

     A metabolite of bradykinin Bradykinin Fragment (1-5) (trifluoroacetate salt) Chemical Structure
  48. GC45887 Bufuralol-d9 (hydrochloride) An internal standard for the quantification of bufuralol Bufuralol-d9 (hydrochloride) Chemical Structure
  49. GC43140 Captopril Disulfide

    SQ 14,551

     Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril. Captopril Disulfide Chemical Structure
  50. GC45398 Captopril-d3   Captopril-d3 Chemical Structure
  51. GC49564 Carazolol-d7

    (±)-Carazolol-d7

     An internal standard for the quantification of carazolol Carazolol-d7 Chemical Structure
  52. GC47045 Carvedilol-d5 An internal standard for the quantification of carvedilol Carvedilol-d5 Chemical Structure
  53. GC52006 CB-096 An inhibitor of RAN translation CB-096 Chemical Structure
  54. GC43247 Chlorthalidone Impurity G Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone Impurity G Chemical Structure
  55. GC43270 Ciprostene (calcium salt)

    Ciprostene calcium, U61431F

     Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene (calcium salt) Chemical Structure
  56. GC47100 Clevidipine-d7

    rac-Clevidipine-d7

     A neuropeptide with diverse biological activities Clevidipine-d7 Chemical Structure
  57. GC47103 Clonidine-d4 (hydrochloride) An internal standard for the quantification of clonidine Clonidine-d4 (hydrochloride) Chemical Structure
  58. GC47116 Coenzyme Q10-d6

    CoQ10-d6, Ubidecarenone-d6, Ubiquinone-10-d6, Ubiquinone Q10-d6

     An internal standard for the quantification of CoQ10 Coenzyme Q10-d6 Chemical Structure
  59. GC47120 Conivaptan-d4 An internal standard for the quantification of conivaptan Conivaptan-d4 Chemical Structure
  60. GC47175 Deacetylforskolin

    7-Deactylcoleonol, Forskolin D

     A diterpene with diverse biological activities Deacetylforskolin Chemical Structure
  61. GC46126 Debrisoquin (hemisulfate)

    Isocaramidine sulfate, Ro 5-3307/1

     A post-ganglionic sympathetic blocker Debrisoquin (hemisulfate) Chemical Structure
  62. GC43399 Dehydro Amlodipine (fumarate) Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. Dehydro Amlodipine (fumarate) Chemical Structure
  63. GC49866 Desmethyl Carvedilol

    BM 14242, O-desmethyl Carvedilol

     An active metabolite of carvedilol Desmethyl Carvedilol Chemical Structure
  64. GC49459 Desmopressin (trifluoroacetate salt)

    Adiuretin, DDAVP

     A vasopressin receptor agonist Desmopressin (trifluoroacetate salt) Chemical Structure
  65. GC62026 Devaleryl Valsartan Impurity

    Valsartan Impurity B

     Devaleryl Valsartan Impurity is an intermediate in the synthesis of Valsartan. Devaleryl Valsartan Impurity Chemical Structure
  66. GC46131 Diazoxide-d3 An internal standard for the quantification of diazoxide Diazoxide-d3 Chemical Structure
  67. GC45427 Dihydrolycorine   Dihydrolycorine Chemical Structure
  68. GC49045 Dopastin

    NSC 252927

     A bacterial metabolite and an inhibitor of dopamine β-hydroxylase Dopastin Chemical Structure
  69. GC47268 Doxazosin-d8 (hydrochloride) An internal standard for the quantification of doxazosin Doxazosin-d8 (hydrochloride) Chemical Structure
  70. GC43601 Enalaprilat (hydrate) Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat (hydrate) Chemical Structure
  71. GC43608 Endothelin-3 (human, rat) (trifluoroacetate salt)

    ET-3

     Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively). Endothelin-3 (human, rat) (trifluoroacetate salt) Chemical Structure
  72. GC52035 Esmolol Acid (hydrochloride)

    ASL 8123

     An active metabolite of esmolol Esmolol Acid (hydrochloride) Chemical Structure
  73. GC47307 Esmolol-d7 (hydrochloride) An internal standard for the quantification of esmolol Esmolol-d7 (hydrochloride) Chemical Structure
  74. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  75. GC60842 Finerenone

    BAY 94-8862

     Finerenone (BAY 94-8862) is a third-generation selective, orally active, nonsteroidal mineralocorticoid receptor (MR) antagonist with an IC50 of 18 nM. Finerenone Chemical Structure
  76. GC45761 Flupirtine-d4 (hydrochloride)

    D 9998-d4 hydrochloride

     An internal standard for the quantification of flupirtine Flupirtine-d4 (hydrochloride) Chemical Structure
  77. GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril Fosinopril-d7 (sodium salt) Chemical Structure
  78. GC63298 Ganoderic acid N Ganoderic acid N is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid N Chemical Structure
  79. GC49117 Guanadrel An antihypertensive agent Guanadrel Chemical Structure
  80. GC47416 Guanfacine-13C,15N3 An internal standard for the quantification of guanfacine Guanfacine-13C,15N3 Chemical Structure
  81. GC45678 Guanoclor

    Guanochlor

     A guanidinium antihypertensive Guanoclor Chemical Structure
  82. GC46155 H-Ile-Pro-Pro-OH (trifluoroacetate salt)

    IPP

     A neuropeptide with diverse biological activities H-Ile-Pro-Pro-OH (trifluoroacetate salt) Chemical Structure
  83. GC47438 H-Val-Pro-Pro-OH (trifluoroactetate salt)

    VPP

     A neuropeptide with diverse biological activities H-Val-Pro-Pro-OH (trifluoroactetate salt) Chemical Structure
  84. GC43803 HA-1077 (hydrochloride)

    Fasudil

     Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. HA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator. HA-1077 (hydrochloride) Chemical Structure
  85. GC47439 Hydralazine-d4 (hydrochloride)

    1-Hydrazinophthalazine-d4

     A neuropeptide with diverse biological activities Hydralazine-d4 (hydrochloride) Chemical Structure
  86. GC47440 Hydrocortisone-d4

    Cortisol-d4

     An internal standard for the quantification of hydrocortisone Hydrocortisone-d4 Chemical Structure
  87. GC47441 Hydroflumethiazide-13C-d2

    Methforylthiazidine-13C,d2; Rontyl-13C,d2

     An internal standard for the quantification of hydroflumethiazide Hydroflumethiazide-13C-d2 Chemical Structure
  88. GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine Hydroxydehydro Nifedipine Carboxylate Chemical Structure
  89. GC43890 ICI 216140 Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. ICI 216140 Chemical Structure
  90. GC49195 Indapamide-13C-d3 An internal standard for the quantification of indapamide Indapamide-13C-d3 Chemical Structure
  91. GC49493 IRL 1620 (trifluoroacetate salt)

    PMZ-1620, SPI 1620, Suc-Glu9, Ala11,15-ET-1(8-21)

     A peptide ETB receptor agonist IRL 1620 (trifluoroacetate salt) Chemical Structure
  92. GC49343 Isoproterenol-d7 (hydrochloride)

    Isoprenaline-d7

     An internal standard for the quantification of isoproterenol Isoproterenol-d7 (hydrochloride) Chemical Structure
  93. GC52310 L-Arginine-13C6 (hydrochloride)

    L-(+)-Arginine-13C6

     An internal standard for the quantification of L-arginine L-Arginine-13C6 (hydrochloride) Chemical Structure
  94. GC49374 L-Arginine-d7 (hydrochloride)

    L-(+)-Arginine-d7

     An internal standard for the quantification of L-arginine L-Arginine-d7 (hydrochloride) Chemical Structure
  95. GC47534 Labetalol-d5 (hydrochloride)

    AH 5158A-d5, SCH 15719W-d5

     A neuropeptide with diverse biological activities Labetalol-d5 (hydrochloride) Chemical Structure
  96. GC45501 Lisinopril-d5   Lisinopril-d5 Chemical Structure
  97. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  98. GC44112 Mabuterol Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). Mabuterol Chemical Structure
  99. GC47597 Manidipine-d4

    Franidipine-d4, (±)-Manidipine-d4

     An internal standard for the quantification of manidipine Manidipine-d4 Chemical Structure
  100. GC41639 Methyldopate

    αMethyldopa ethyl ester

     Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension. Methyldopate Chemical Structure
  101. GC46170 Methylspinazarin

    Methylspinazaline

     A bacterial metabolite and COMT inhibitor Methylspinazarin Chemical Structure

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