Hypertension
Products for Hypertension
- Cat.No. Product Name Information
- GC48283 α-Linolenic Acid-d14 An internal standard for the quantification of αLinolenic acid
- GC40105 βARK1 Inhibitor βARK1 Inhibitor (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor.
- GC52404 γ-Glu-Phe (trifluoroacetate salt) A dipeptide with metabolism-altering activity
- GC41661 (±)-4-hydroxy Propranolol β-D-Glucuronide (±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
- GC46273 (±)-Atenolol-d7 An internal standard for the quantification of (±)-atenolol
- GC46289 (±)-Felodipine-d5 An internal standard for the quantification of (±)-felodipine
- GC46307 (±)-Propranolol-d7 An internal standard for the quantification of propranolol
- GC40434 (±)16-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
- GC40437 (±)5(6)-DiHET lactone 5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET.
- GC41722 (R,S)-Carvedilol Glucuronide (R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
- GC18634 11-deoxy Prostaglandin E1 11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1.
- GC41401 11-deoxy Prostaglandin F1α 11-deoxy PGF1α is a synthetic analog of PGF1α.
- GC41402 11-deoxy Prostaglandin F1β 11-deoxy PGF1β is a synthetic analog of PGF1β.
- GC41935 15-keto Treprostinil (sodium salt) 15-keto Treprostinil is an impurity found in treprostinil, which is a stable analog of prostaglandin I2 with a longer plasma half-life.
- GC41159 16,16-dimethyl Prostaglandin D2 16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2.
- GC18635 18-hydroxy-11-deoxy Corticosterone 18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland.
- GC52048 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase.
- GC42498 5-chloro Hydrochlorothiazide 5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
- GC41483 5-hydroxy Propranolol 5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist.
- GC42563 5-methyl-2-HOBA (hydrochloride) 5-methyl-2-HOBA is an isoketal scavenger.
- GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2.
- GC48486 AAA A GPR75 antagonist
- GC49406 ACT-373898 A metabolite of macitentan
- GC42738 Adrenomedullin (13-52) (human) (trifluoroacetate salt) Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52).
- GC46820 AHU377-d4 AHU377-d4 (AHU-377-d4) is the deuterium labeled Sacubitril.
- GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities
- GC49638 Ambrisentan-d3 An internal standard for the quantification of ambrisentan
- GC46845 Amlodipine-d4 (maleate) An internal standard for the quantification of amlodipine
- GC52415 Angiotensin A (trifluoroacetate salt) An AT1 and AT2 receptor agonist and active metabolite of angiotensin II
- GC48997 Argipressin (acetate) A peptide hormone with vasoconstrictive and antidiuretic activities
- GC39554 AT2 receptor agonist C21 An AT2 receptor agonist
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GC42913
Benazeprilat
Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.
- GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function.
- GC42966 Bopindolol (malonate) Bopindolol is a non-selective β-adrenergic receptor antagonist.
- GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator
- GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin
- GC45887 Bufuralol-d9 (hydrochloride) An internal standard for the quantification of bufuralol
- GC43140 Captopril Disulfide Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril.
- GC45398 Captopril-d3
- GC49564 Carazolol-d7 An internal standard for the quantification of carazolol
- GC47045 Carvedilol-d5 An internal standard for the quantification of carvedilol
- GC52006 CB-096 An inhibitor of RAN translation
- GC43247 Chlorthalidone Impurity G Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects.
- GC43270 Ciprostene (calcium salt) Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.
- GC47103 Clonidine-d4 (hydrochloride) An internal standard for the quantification of clonidine
- GC47116 Coenzyme Q10-d6 An internal standard for the quantification of CoQ10
- GC47120 Conivaptan-d4 An internal standard for the quantification of conivaptan
- GC47175 Deacetylforskolin A diterpene with diverse biological activities
- GC46126 Debrisoquin (hemisulfate) A post-ganglionic sympathetic blocker
- GC43399 Dehydro Amlodipine (fumarate) Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.
- GC49866 Desmethyl Carvedilol An active metabolite of carvedilol
- GC49459 Desmopressin (trifluoroacetate salt) A vasopressin receptor agonist
- GC46131 Diazoxide-d3 An internal standard for the quantification of diazoxide
- GC45439 Docosahexaenoic Acid-d5 MaxSpec• Standard Docosahexaenoic Acid-d5 MaxSpec• Standard (DHA-d5) is the deuterium labeled Docosahexaenoic Acid.
- GC49045 Dopastin A bacterial metabolite and an inhibitor of dopamine β-hydroxylase
- GC47268 Doxazosin-d8 (hydrochloride) An internal standard for the quantification of doxazosin
- GC43608 Endothelin-3 (human, rat) (trifluoroacetate salt) Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively).
- GC52035 Esmolol Acid (hydrochloride) An active metabolite of esmolol
- GC47307 Esmolol-d7 (hydrochloride) An internal standard for the quantification of esmolol
- GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil
- GC45761 Flupirtine-d4 (hydrochloride) An internal standard for the quantification of flupirtine
- GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril
- GC49117 Guanadrel An antihypertensive agent
- GC47416 Guanfacine-13C,15N3 An internal standard for the quantification of guanfacine
- GC45678 Guanoclor A guanidinium antihypertensive
- GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. HA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.
- GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone
- GC47441 Hydroflumethiazide-13C-d2 An internal standard for the quantification of hydroflumethiazide
- GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine
- GC43890 ICI 216140 Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity.
- GC49195 Indapamide-13C-d3 An internal standard for the quantification of indapamide
- GC49493 IRL 1620 (trifluoroacetate salt) A peptide ETB receptor agonist
- GC49343 Isoproterenol-d7 (hydrochloride) An internal standard for the quantification of isoproterenol
- GC52310 L-Arginine-13C6 (hydrochloride) An internal standard for the quantification of L-arginine
- GC49374 L-Arginine-d7 (hydrochloride) An internal standard for the quantification of L-arginine
- GC45501 Lisinopril-d5
- GC52281 Losartan Azide A potential impurity in commercial preparations of losartan
- GC44112 Mabuterol Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR).
- GC47597 Manidipine-d4 An internal standard for the quantification of manidipine
- GC41639 Methyldopate Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.
- GC46170 Methylspinazarin A bacterial metabolite and COMT inhibitor
- GC49194 Metolazone-d7 An internal standard for the quantification of metolazone
- GC48469 Moexipril-d5 An internal standard for the quantification of moexipril
- GC47712 Mycophenolate Mofetil-d4 An internal standard for the quantification of mycophenolate mofetil
- GC44351 N-Desmethyl Sildenafil (citrate) N-Desmethyl sildenafil is a major metabolite of sildenafil.
- GC44396 N-Hippuryl-His-Leu (hydrate) N-Hippuryl-His-Leu (hydrate) is a synthetic substrate for angiotensin-converting enzyme (ACE) that has been used in the in vitro identification of ACE inhibitors.,
- GC47784 N-methyl-2-HOBA (hydrochloride) A methylated form of 2-HOBA
- GC48837 NG,NG-dimethyl-L-Arginine-d6 (hydrochloride) NG,NG-dimethyl-L-Arginine-d6 (hydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride.
- GC49090 Nilvadipine-d4 An internal standard for the quantification of nilvadipine
- GC47776 Nisoldipine-d6 An internal standard for the quantification of nisoldipine
- GC44446 NO-Losartan A Angiotensin II is a hormone that plays an important role in regulating blood pressure.
- GC52019 Norpropranolol (hydrochloride) An active metabolite of propranolol
- GC48801 Nylidrin An agonist of β-ARs and antagonist of NR1A/2B subunit-containing NMDA receptors
- GC49349 O-Desethyl Sildenafil A metabolite of sildenafil
- GC49428 O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine A major metabolite of amlodipine
- GC47824 Olmesartan Medoxomil-d6 An internal standard for the quantification of olmesartan medoxomil
- GC49677 Olmesartan-d6 An internal standard for the quantification of olmesartan
- GC48847 Oxprenolol-d7 An internal standard for the quantification of oxprenolol
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GC44599
Perindoprilat
Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension.
- GC46202 Phenoxybenzamine-d5 (hydrochloride) An internal standard for the quantification of phenoxybenzamine