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Neuroscience

Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).

Targets for  Neuroscience

Products for  Neuroscience

  1. Cat.No. Product Name Information
  2. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene  Chemical Structure
  3. GC14752 2,4-Dihydroxyphenylacetyl-L-asparagine glutamate receptors blocker 2,4-Dihydroxyphenylacetyl-L-asparagine  Chemical Structure
  4. GC49159 2-(1-Piperazinyl)pyrimidine An α2-AR antagonist and active metabolite of azapirones 2-(1-Piperazinyl)pyrimidine  Chemical Structure
  5. GC46505 2-(Isopentylamino)naphthalene-1,4-dione A vitamin K analog 2-(Isopentylamino)naphthalene-1,4-dione  Chemical Structure
  6. GC17308 2-3-Pyridinedicarboxylic acid 2-3-Pyridinedicarboxylic acid  Chemical Structure
  7. GC49481 2-Aminotetralin A neuromodulatory agent 2-Aminotetralin  Chemical Structure
  8. GC14873 2-CMDO Dopamine D2-like receptor antagonist 2-CMDO  Chemical Structure
  9. GC40473 2-hydroxy Lignoceric Acid 2-hydroxy Lignoceric acid is an α-hydroxy very long chain fatty acid that is normally present in the mammalian nervous system. 2-hydroxy Lignoceric Acid  Chemical Structure
  10. GC11267 2-Hydroxysaclofen GABAB receptor antagonist 2-Hydroxysaclofen  Chemical Structure
  11. GC38108 2-Methyl-5-HT 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT  Chemical Structure
  12. GC11176 2-Methyl-5-hydroxytryptamine hydrochloride 2-Methyl-5-hydroxytryptamine hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-hydroxytryptamine hydrochloride  Chemical Structure
  13. GC49840 2-Methylbutyrylglycine A metabolite of isoleucine 2-Methylbutyrylglycine  Chemical Structure
  14. GC52170 2-Nitroamino-2-imidazoline 2-Nitroamino-2-imidazoline  Chemical Structure
  15. GC11001 2-Pyridylethylamine dihydrochloride

    Histamine H1 receptor agonist

    2-Pyridylethylamine dihydrochloride  Chemical Structure
  16. GC14959 2-[1-(4-Piperonyl)piperazinyl]benzothiazole 5-HT4 receptor 2-[1-(4-Piperonyl)piperazinyl]benzothiazole  Chemical Structure
  17. GC42087 21-desacetyl Deflazacort 21-desacetyl Deflazacort is the active glucocorticoid derived from the prodrug deflazacort. 21-desacetyl Deflazacort  Chemical Structure
  18. GC41210 22-HDHA 22-HDHA is an oxidation product of docosahexaenoic acid. 22-HDHA  Chemical Structure
  19. GC40571 24(S),25-epoxy Cholesterol

    24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.

    24(S),25-epoxy Cholesterol  Chemical Structure
  20. GC41614 24-dehydro Cholesterol 24-dehydro Cholesterol is a molecule similar to cholesterol. 24-dehydro Cholesterol  Chemical Structure
  21. GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6  Chemical Structure
  22. GC33673 24-Hydroxycholesterol 24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol  Chemical Structure
  23. GC31021 2614W94 2614W94 is a selective, reversible inhibitor of monoamine oxidase-A with a competitive mechanism of inhibition and IC50 of 5 nM and Ki of 1.6 nM with serotonin as substrate. 2614W94  Chemical Structure
  24. GC15856 3'-Fluorobenzylspiperone maleate

    ligand for the D2 receptor

    3'-Fluorobenzylspiperone maleate  Chemical Structure
  25. GC15606 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride dopamine uptake and transport inhibitor 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride  Chemical Structure
  26. GC41480 3'-hydroxy Lidocaine 3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. 3'-hydroxy Lidocaine  Chemical Structure
  27. GC42242 3'-sulfo Galactosylsphingosine (ammonium salt) 3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. 3'-sulfo Galactosylsphingosine (ammonium salt)  Chemical Structure
  28. GC42201 3,3'-Diiodo-L-thyronine 3,3'-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3'-T2. 3,3'-Diiodo-L-thyronine  Chemical Structure
  29. GC33703 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifoliaWILLD, with anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid  Chemical Structure
  30. GC14343 3,4-dihydro Naratriptan selective serotonin 5-HT1B agonist 3,4-dihydro Naratriptan  Chemical Structure
  31. GC46557 3,4-Dihydroquinolin-2(1H)-one A building block 3,4-Dihydroquinolin-2(1H)-one  Chemical Structure
  32. GC49169 3,8’-Biapigenin A biflavonoid with diverse biological activities 3,8’-Biapigenin  Chemical Structure
  33. GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides 3-(3-Hydroxyphenyl)propionic Acid sulfate  Chemical Structure
  34. GC42198 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) An inactive metabolite of baclofen 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)  Chemical Structure
  35. GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide 3-Amino-2,6-Piperidinedione  Chemical Structure
  36. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid  Chemical Structure
  37. GC42248 3-Aminopropylphosphonic Acid 3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay). 3-Aminopropylphosphonic Acid  Chemical Structure
  38. GC15569 3-AQC 5-HT3 antagonist 3-AQC  Chemical Structure
  39. GC11757 3-Bromocytisine α4β4, α4β2 and α7 nACh receptor agonist 3-Bromocytisine  Chemical Structure
  40. GC12641 3-CPMT dopamine uptake inhibitor 3-CPMT  Chemical Structure
  41. GC42258 3-Cysteinylacetaminophen (trifluoroacetate salt) An acetaminophen-protein adduct 3-Cysteinylacetaminophen (trifluoroacetate salt)  Chemical Structure
  42. GC60499 3-Hydroxy agomelatine 3-Hydroxy agomelatine is a metabolite of Agomelatine. 3-Hydroxy agomelatine  Chemical Structure
  43. GC68328 3-Hydroxy agomelatine-d3 3-Hydroxy agomelatine-d3  Chemical Structure
  44. GC42274 3-hydroxy Darifenacin 3-hydroxy Darifenacin is a metabolite of darifenacin. 3-hydroxy Darifenacin  Chemical Structure
  45. GC41565 3-hydroxy Medetomidine 3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine. 3-hydroxy Medetomidine  Chemical Structure
  46. GC18311 3-hydroxy Octanoic Acid 3-hydroxy Octanoic acid is a hydroxylated fatty acid that has been found in LPS from P. 3-hydroxy Octanoic Acid  Chemical Structure
  47. GC40487 3-hydroxy Undecanoic Acid 3-hydroxy Undecanoic acid is a hydroxylated fatty acid that has been found in S. 3-hydroxy Undecanoic Acid  Chemical Structure
  48. GC52048 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase. 3-hydroxy-4-Methoxyphenethylamine (hydrochloride)  Chemical Structure
  49. GC45336 3-hydroxy-DL-Kynurenine 3-hydroxy-DL-Kynurenine, ametabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-hydroxy-DL-Kynurenine  Chemical Structure
  50. GC42294 3-Iodothyronamine (hydrochloride) 3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. 3-Iodothyronamine (hydrochloride)  Chemical Structure
  51. GC11223 3-MATIDA mGlu1 receptor antagonist 3-MATIDA  Chemical Structure
  52. GC49869 3-Methoxytyrosine An active metabolite of L-DOPA 3-Methoxytyrosine  Chemical Structure
  53. GC12506 3-Methyl-GABA GABA aminotransferase activator 3-Methyl-GABA  Chemical Structure
  54. GC49149 3-Methylglutaconic Acid A branched-chain organic acid 3-Methylglutaconic Acid  Chemical Structure
  55. GC42307 3-O-methyl-L-DOPA (hydrate) 3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA (hydrate)  Chemical Structure
  56. GC60505 3-O-Methyldopa 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa  Chemical Structure
  57. GC60506 3-O-Methyldopa D3 3-O-Methyldopa D3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa D3  Chemical Structure
  58. GC10484 3-pyr-Cytisine

    α4β2 receptors agonist

    3-pyr-Cytisine  Chemical Structure
  59. GC52391 306-O12B-3 An ionizable cationic lipidoid 306-O12B-3  Chemical Structure
  60. GC18817 3β-hydroxy-5-Cholestenoic Acid 3β-hydroxy-5-Cholestenoic acid is an active metabolite of cholesterol formed when cholesterol is metabolized by the cytochrome P450 (CYP) isomer CYP27A1. 3β-hydroxy-5-Cholestenoic Acid  Chemical Structure
  61. GC49367 4’-hydroxy Atomoxetine Glucuronide (hydrate) A metabolite of atomoxetine 4’-hydroxy Atomoxetine Glucuronide (hydrate)  Chemical Structure
  62. GC49252 4’-hydroxy Trazodone A metabolite of trazodone 4’-hydroxy Trazodone  Chemical Structure
  63. GC40768 4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid 4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5. 4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid  Chemical Structure
  64. GC45340 4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid   4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid  Chemical Structure
  65. GC62799 4,4-Diphenylbutylamine hydrochloride 4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively. 4,4-Diphenylbutylamine hydrochloride  Chemical Structure
  66. GC49752 4,5-Desisopropylidene Topiramate An inactive metabolite of topiramate 4,5-Desisopropylidene Topiramate  Chemical Structure
  67. GC30952 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM. 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine  Chemical Structure
  68. GC31208 4-(6-Bromo-2-benzothiazolyl)benzenamine 4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome. 4-(6-Bromo-2-benzothiazolyl)benzenamine  Chemical Structure
  69. GC40045 4-(Dimethylamino)-1-methylpyridinium (iodide) 4-(Dimethylamino)-1-methylpyridinium is a monoquaternary pyridinium salt with anticholinesterase and antiproliferative activities. 4-(Dimethylamino)-1-methylpyridinium (iodide)  Chemical Structure
  70. GC33504 4-Acetamidobutanoic acid (N-acetyl GABA) 4-Acetamidobutanoic acid (N-acetyl GABA) (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities. 4-Acetamidobutanoic acid (N-acetyl GABA)  Chemical Structure
  71. GC15383 4-Acetyl-1,1-dimethylpiperazinium iodide nicotinic agonist 4-Acetyl-1,1-dimethylpiperazinium iodide  Chemical Structure
  72. GC42338 4-Aminobenzoic Acid hydrazide 4-Aminobenzoic Acid hydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 μM. 4-Aminobenzoic Acid hydrazide  Chemical Structure
  73. GC49657 4-chloro Trazodone isomer (hydrochloride) An isomer of trazodone 4-chloro Trazodone isomer (hydrochloride)  Chemical Structure
  74. GC13348 4-DAMP M3 cholinergic receptor antagonist 4-DAMP  Chemical Structure
  75. GC42373 4-epi Minocycline 4-epi Minocycline is the main degradation product of and a potential impurity in commercial preparations of minocycline. 4-epi Minocycline  Chemical Structure
  76. GC48824 4-hydroxy Estrone A metabolite of estrone 4-hydroxy Estrone  Chemical Structure
  77. GC42411 4-hydroxy Nonenal Alkyne

    4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

    4-hydroxy Nonenal Alkyne  Chemical Structure
  78. GC40879 4-hydroxy Solifenacin N-oxide 4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin . 4-hydroxy Solifenacin N-oxide  Chemical Structure
  79. GC42417 4-hydroxy-3-Methoxyphenylglycol (piperazine salt) 4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate. 4-hydroxy-3-Methoxyphenylglycol (piperazine salt)  Chemical Structure
  80. GC60519 4-Hydroxyderricin 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin  Chemical Structure
  81. GC63628 4-Hydroxymidazolam 4-Hydroxymidazolam  Chemical Structure
  82. GC39307 4-Methylamino antipyrine 4-Methylamino antipyrine is an active metabolite of Metamizole. 4-Methylamino antipyrine  Chemical Structure
  83. GC60523 4-Methylamino antipyrine hydrochloride An active metabolite of metamizole 4-Methylamino antipyrine hydrochloride  Chemical Structure
  84. GC11606 4-Methylbenzylidene camphor ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities. 4-Methylbenzylidene camphor  Chemical Structure
  85. GC12737 4-Methylhistamine dihydrochloride H4 receptor agonist 4-Methylhistamine dihydrochloride  Chemical Structure
  86. GC42443 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside  Chemical Structure
  87. GC40510 4-Methylumbelliferyl-α-D-Galactopyranoside 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. 4-Methylumbelliferyl-α-D-Galactopyranoside  Chemical Structure
  88. GC42447 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases. 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside  Chemical Structure
  89. GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin 4-oxo Isotretinoin  Chemical Structure
  90. GC14311 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride dopamine release inhibitor 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride  Chemical Structure
  91. GC46675 4-Phenyl-2-pyrrolidinone A precursor and synthetic intermediate 4-Phenyl-2-pyrrolidinone  Chemical Structure
  92. GC16040 4F 4PP oxalate 5-HT2A antagonist 4F 4PP oxalate  Chemical Structure
  93. GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol  Chemical Structure
  94. GC46715 5α,6β-Dihydroxycholestanol-d7 An internal standard for the quantification of 5α,6β-dihydroxycholestanol 5α,6β-Dihydroxycholestanol-d7  Chemical Structure
  95. GC48843 5α-Androst-16-en-3α-ol A pheromone with diverse biological activities 5α-Androst-16-en-3α-ol  Chemical Structure
  96. GC49540 5α-Androst-2-ene-17-one A steroid and synthetic intermediate 5α-Androst-2-ene-17-one  Chemical Structure
  97. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam  Chemical Structure
  98. GC60527 5,7-Dimethoxyluteolin 5,7-Dimethoxyluteolin, a 5,7-dimethylluteolin derivative, is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM. 5,7-Dimethoxyluteolin  Chemical Structure
  99. GC14814 5-Carboxamidotryptamine maleate 5-HT1 agonist 5-Carboxamidotryptamine maleate  Chemical Structure
  100. GC31234 5-HT1A modulator 1 5-HT1A modulator 1 displays very high affinities for the 5HT1A, adrenergic α1 and dopamine D2 receptor with IC50s of 2 ±0.3 nM, 10 ± 3 nM and 40 ±9 nM, respectively. 5-HT1A modulator 1  Chemical Structure
  101. GC60028 5-HT1A modulator 2 hydrochloride 5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT, is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding. 5-HT1A modulator 2 hydrochloride  Chemical Structure

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