5-HT Receptor
5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.
Products for 5-HT Receptor
- Cat.No. Product Name Information
- GC63599 Bufotenidine
- GC11191 Buspirone HCl Buspirone HCl is a 5-HT1A receptor agonist.
- GC11231 BW 723C86 hydrochloride BW 723C86 hydrochloride is a potent and a selective 5-HT2B receptor agonist.
- GC15985 Cariprazine An atypical antipsychotic
- GC35610 Cariprazine hydrochloride An atypical antipsychotic
- GC46007 Cariprazine-d6 An internal standard for the quantification of cariprazine
- GC63961 Cerlapirdine Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor.
- GC12276 CGS 12066B dimaleate CGS 12066 (dimaleate) dimaleate is a selective 5-HT1B receptor agonist with an IC50 of 51 nM.
- GC30280 Chlorpromazine D6 hydrochloride An internal standard for the quantification of chlorpromazine
-
GC14216
Chlorpromazine HCl
dopamine receptor antagonist
- GC16135 Cinanserin hydrochloride 5-HT2 antagonist
- GC25253 Cinitapride Hydrogen Tartrate Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
- GC38753 cis-Urocanic acid cis-Urocanic acid is a 5-HT2A receptor agonist.
- GC13533 Cisapride 5-HT4 receptor agonist
- GC25259 Cisapride hydrate Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
- GC14035 Citalopram hydrobromide 5-HT uptake inhibitor
- GC13583 CJ 033466 5-HT4 partial agonist
- GC31037 Clocapramine (Clocarpramine)
- GC15107 Clomipramine HCl Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM.
-
GC10822
Clozapine N-oxide (CNO)
A metabolite of clozapine and muscarinic DREADD agonist
- GC11802 CP 135807 5-HT1D receptor agonist
- GC10068 CP 93129 dihydrochloride 5-HT1B agonist, potent and highly selective
- GC16653 CP 94253 hydrochloride 5-HT1B agonist
- GC17183 CP-809101 A potent 5-HT2C receptor agonist
- GC12782 CP-809101 hydrochloride A potent 5-HT2C receptor agonist
- GC38760 Cyamemazine Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore.
- GC12632 Cyanopindolol hemifumarate 5-HT1A/1B antagonist and β-adrenoceptor antagonist
- GC10743 Cyclobenzaprine HCl Cyclobenzaprine HCl (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant.
- GC65565 Cyproheptadine Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects.
- GC43353 Cyproheptadine (hydrochloride hydrate) Cyproheptadine (hydrochloride hydrate) is an antihistamine and is an antagonist of serotonin and histamine2.
- GC10698 Cyproheptadine hydrochloride serotonin and histamine antagonist as well as antimuscarinic reagent
- GC17061 Dapoxetine HCl Selective serotonin reuptake inhibitor
- GC39705 Dehydroaripiprazole Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole.
- GC33722 Deramciclane (EGIS-3886) Deramciclane (EGIS-3886) has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist.
- GC11570 Desvenlafaxine serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor
- GC14262 Desvenlafaxine Succinate serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor
- GC62932 Didesmethyl cariprazine Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety.
- GC14558 Dihydroergotamine mesylate Partial α-adrenergic agonist,partial D2 dopaminergic receptor agonist, competitive 5-HT antagonist.
- GC13390 DOB hydrochloride Selective 5-HT2 receptor agonist
- GC30412 Dolasetron (MDL-73147) Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
- GC30413 Dolasetron Mesylate (MDL-73147EF) Dolasetron Mesylate (MDL-73147EF) (MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
- GC30198 Dolasetron Mesylate hydrate Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
- GC35894 Donitriptan Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively.
- GC13265 Donitriptan hydrochloride 5-HT1B/1D receptors agonist, potent and selective
- GC10679 DR 4485 hydrochloride DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14).
- GC65014 DSP-1053 DSP-1053, a benzylpiperidine derivative, is a potent?Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM.
- GC13871 Duloxetine HCl Duloxetine HCl ((S)-Duloxetine HCl) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
- GC11516 DV 7028 hydrochloride 5-HT2A receptor antagonist
- GC17053 Eletriptan HBr Eletriptan HBr (Eletriptan HBr) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.
- GC30982 Eltoprazine (DU 28853) Eltoprazine (DU 28853)(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.
- GC18244 Eltoprazine (hydrochloride) Eltoprazine is a phenylpiperazine compound that acts as a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Kis = 40, 52, and 81 nM, respectively).
- GC10495 EMD 281014 hydrochloride 5-HT2A antagonist
- GC16045 EMD 386088 hydrochloride EMD 386088 hydrochloride is a potent serotonin 6 receptor (5-HT6R) agonist.
-
GC15367
EMDT oxalate
5-HT6 agonist
- GC31218 Eplivanserin (SR-46349) Eplivanserin (SR-46349) (SR-46349) is a potent, selective and orally active 5-HT2A receptor antagonist, with an IC50 of 5.8 nM in rat cortical membrane, and a Kd of 1.14 nM.
- GC50084 Eplivanserin hemifumarate Potent and selective 5-HT2A antagonist
- GC34575 Eplivanserin mixture Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1.
- GC30939 Eptapirone (F 11440) Eptapirone (F 11440) (F11440) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.
- GC30910 Eucalyptol (1,8-Cineole) A bicyclic monoterpene with diverse biological activities
- GC31032 F-15599 F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist, with Ki of 3.4 nM.
- GC62967 F13714 fumarate F13714 fumarate, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.
- GC39748 Facinicline hydrochloride Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR.
- GC13109 Fananserin 5-HT2A receptor antagonist
- GC63682 Felcisetrag Felcisetrag (TD-8954) is an orally active, potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties.
- GC14512 Fenspiride HCl α adrenergic and H1 histamine receptor antagonist
- GC32439 Ferulic acid sodium (Sodium ferulate) Ferulic acid sodium (Sodium ferulate) is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
- GC31011 FK1052 hydrochloride FK1052 hydrochloride ((±)-FK1052) is the racemate of Fabesetron hydrochloride, which is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
- GC60846 Flesinoxan Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM.
- GC11100 Flibanserin full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A.
- GC68364 Flibanserin-d4-1
- GC12535 Flopropione 5-HT receptor antagonist
- GC38912 Flumexadol Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A receptor.
- GC11709 Fluoxetine HCl Serotonin reuptake inhibitor,selective
- GC13092 Fluvoxamine Selective serotonin reuptake inhibitor
- GC15025 Fluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant
- GC25434 Frovatriptan Succinate Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
- GC38781 Frovatriptan succinate hydrate An agonist of 5-HT1B and 5-HT1D receptors
- GC38227 Gamma-Mangostin A xanthone with diverse biological activities
- GC38529 Geissoschizine methyl ether Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects.
- GC11624 GR 113808 5-HT4 receptor antagonist
- GC15248 GR 125487 sulfamate 5-HT4 receptor antagonist
- GC61464 GR 125743 GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively.
- GC17140 GR 127935 hydrochloride 5-HT1B/1D receptor antagonist
- GC14373 GR 46611 GR 46611 is a 5-HT1D receptor agonist. GR 46611 can be used in the research of bladder hyperactivity, leukemia.
- GC17524 GR 55562 dihydrochloride 5-HT1B (5-HT1Dβ) silent antagonist
- GC12398 Granisetron
- GC16029 Granisetron HCl Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
- GC19176 GSK163090 GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively.
- GC30762 Harmine (Telepathine) A unique regulator of PPARγ expression
- GC38413 Harmine hydrochloride
- GC60915 Hydroxy ziprasidone Hydroxy ziprasidone is an impurity of Ziprasidone.
- GC36291 Idalopirdine A 5-HT6 receptor antagonist
- GC63015 Iferanserin Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor.
- GC15463 Iloperidone Dopamine (D2) and serotonin (5HT2) receptor antagonist
- GC10799 Iloperidone hydrochloride D(2)/5-HT(2) receptor antagonistis
- GC12885 Imipramine (hydrochloride) serotonin and norepinephrine transporters inhibitor
- GC14093 Indatraline hydrochloride Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)
- GC61565 Indophagolin Indophagolin is a potent, indoline-containing autophagy inhibitor (IC50=140 nM). Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 μM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7.
- GC60938 Iprindole Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT.
- GC13133 Ipsapirone 5-HT1A receptor agonist