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5-HT Receptor

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

Products for  5-HT Receptor

  1. Cat.No. Product Name Information
  2. GC63599 Bufotenidine Bufotenidine  Chemical Structure
  3. GC11191 Buspirone HCl Buspirone HCl is a 5-HT1A receptor agonist. Buspirone HCl  Chemical Structure
  4. GC11231 BW 723C86 hydrochloride BW 723C86 hydrochloride is a potent and a selective 5-HT2B receptor agonist. BW 723C86 hydrochloride  Chemical Structure
  5. GC15985 Cariprazine An atypical antipsychotic Cariprazine  Chemical Structure
  6. GC35610 Cariprazine hydrochloride An atypical antipsychotic Cariprazine hydrochloride  Chemical Structure
  7. GC46007 Cariprazine-d6 An internal standard for the quantification of cariprazine Cariprazine-d6  Chemical Structure
  8. GC63961 Cerlapirdine Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine  Chemical Structure
  9. GC12276 CGS 12066B dimaleate CGS 12066 (dimaleate) dimaleate is a selective 5-HT1B receptor agonist with an IC50 of 51 nM. CGS 12066B dimaleate  Chemical Structure
  10. GC30280 Chlorpromazine D6 hydrochloride An internal standard for the quantification of chlorpromazine Chlorpromazine D6 hydrochloride  Chemical Structure
  11. GC14216 Chlorpromazine HCl

    dopamine receptor antagonist

    Chlorpromazine HCl  Chemical Structure
  12. GC16135 Cinanserin hydrochloride 5-HT2 antagonist Cinanserin hydrochloride  Chemical Structure
  13. GC25253 Cinitapride Hydrogen Tartrate Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors Cinitapride Hydrogen Tartrate  Chemical Structure
  14. GC38753 cis-Urocanic acid cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid  Chemical Structure
  15. GC13533 Cisapride 5-HT4 receptor agonist Cisapride  Chemical Structure
  16. GC25259 Cisapride hydrate Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic. Cisapride hydrate  Chemical Structure
  17. GC14035 Citalopram hydrobromide 5-HT uptake inhibitor Citalopram hydrobromide  Chemical Structure
  18. GC13583 CJ 033466 5-HT4 partial agonist CJ 033466  Chemical Structure
  19. GC31037 Clocapramine (Clocarpramine) Clocapramine (Clocarpramine)  Chemical Structure
  20. GC15107 Clomipramine HCl Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine HCl  Chemical Structure
  21. GC10822 Clozapine N-oxide (CNO)

    A metabolite of clozapine and muscarinic DREADD agonist

    Clozapine N-oxide (CNO)  Chemical Structure
  22. GC11802 CP 135807 5-HT1D receptor agonist CP 135807  Chemical Structure
  23. GC10068 CP 93129 dihydrochloride 5-HT1B agonist, potent and highly selective CP 93129 dihydrochloride  Chemical Structure
  24. GC16653 CP 94253 hydrochloride 5-HT1B agonist CP 94253 hydrochloride  Chemical Structure
  25. GC17183 CP-809101 A potent 5-HT2C receptor agonist CP-809101  Chemical Structure
  26. GC12782 CP-809101 hydrochloride A potent 5-HT2C receptor agonist CP-809101 hydrochloride  Chemical Structure
  27. GC38760 Cyamemazine Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine  Chemical Structure
  28. GC12632 Cyanopindolol hemifumarate 5-HT1A/1B antagonist and β-adrenoceptor antagonist Cyanopindolol hemifumarate  Chemical Structure
  29. GC10743 Cyclobenzaprine HCl Cyclobenzaprine HCl (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine HCl  Chemical Structure
  30. GC65565 Cyproheptadine Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine  Chemical Structure
  31. GC43353 Cyproheptadine (hydrochloride hydrate) Cyproheptadine (hydrochloride hydrate) is an antihistamine and is an antagonist of serotonin and histamine2. Cyproheptadine (hydrochloride hydrate)  Chemical Structure
  32. GC10698 Cyproheptadine hydrochloride serotonin and histamine antagonist as well as antimuscarinic reagent Cyproheptadine hydrochloride  Chemical Structure
  33. GC17061 Dapoxetine HCl Selective serotonin reuptake inhibitor Dapoxetine HCl  Chemical Structure
  34. GC39705 Dehydroaripiprazole Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Dehydroaripiprazole  Chemical Structure
  35. GC33722 Deramciclane (EGIS-3886) Deramciclane (EGIS-3886) has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. Deramciclane (EGIS-3886)  Chemical Structure
  36. GC11570 Desvenlafaxine serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor Desvenlafaxine  Chemical Structure
  37. GC14262 Desvenlafaxine Succinate serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor Desvenlafaxine Succinate  Chemical Structure
  38. GC62932 Didesmethyl cariprazine Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety. Didesmethyl cariprazine  Chemical Structure
  39. GC14558 Dihydroergotamine mesylate Partial α-adrenergic agonist,partial D2 dopaminergic receptor agonist, competitive 5-HT antagonist. Dihydroergotamine mesylate  Chemical Structure
  40. GC13390 DOB hydrochloride Selective 5-HT2 receptor agonist DOB hydrochloride  Chemical Structure
  41. GC30412 Dolasetron (MDL-73147) Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Dolasetron (MDL-73147)  Chemical Structure
  42. GC30413 Dolasetron Mesylate (MDL-73147EF) Dolasetron Mesylate (MDL-73147EF) (MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Dolasetron Mesylate (MDL-73147EF)  Chemical Structure
  43. GC30198 Dolasetron Mesylate hydrate Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Dolasetron Mesylate hydrate  Chemical Structure
  44. GC35894 Donitriptan Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively. Donitriptan  Chemical Structure
  45. GC13265 Donitriptan hydrochloride 5-HT1B/1D receptors agonist, potent and selective Donitriptan hydrochloride  Chemical Structure
  46. GC10679 DR 4485 hydrochloride DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14). DR 4485 hydrochloride  Chemical Structure
  47. GC65014 DSP-1053 DSP-1053, a benzylpiperidine derivative, is a potent?Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053  Chemical Structure
  48. GC13871 Duloxetine HCl Duloxetine HCl ((S)-Duloxetine HCl) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine HCl  Chemical Structure
  49. GC11516 DV 7028 hydrochloride 5-HT2A receptor antagonist DV 7028 hydrochloride  Chemical Structure
  50. GC17053 Eletriptan HBr Eletriptan HBr (Eletriptan HBr) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively. Eletriptan HBr  Chemical Structure
  51. GC30982 Eltoprazine (DU 28853) Eltoprazine (DU 28853)(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor. Eltoprazine (DU 28853)  Chemical Structure
  52. GC18244 Eltoprazine (hydrochloride) Eltoprazine is a phenylpiperazine compound that acts as a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Kis = 40, 52, and 81 nM, respectively). Eltoprazine (hydrochloride)  Chemical Structure
  53. GC10495 EMD 281014 hydrochloride 5-HT2A antagonist EMD 281014 hydrochloride  Chemical Structure
  54. GC16045 EMD 386088 hydrochloride EMD 386088 hydrochloride is a potent serotonin 6 receptor (5-HT6R) agonist. EMD 386088 hydrochloride  Chemical Structure
  55. GC15367 EMDT oxalate

    5-HT6 agonist

    EMDT oxalate  Chemical Structure
  56. GC31218 Eplivanserin (SR-46349) Eplivanserin (SR-46349) (SR-46349) is a potent, selective and orally active 5-HT2A receptor antagonist, with an IC50 of 5.8 nM in rat cortical membrane, and a Kd of 1.14 nM. Eplivanserin (SR-46349)  Chemical Structure
  57. GC50084 Eplivanserin hemifumarate Potent and selective 5-HT2A antagonist Eplivanserin hemifumarate  Chemical Structure
  58. GC34575 Eplivanserin mixture Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. Eplivanserin mixture  Chemical Structure
  59. GC30939 Eptapirone (F 11440) Eptapirone (F 11440) (F11440) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential. Eptapirone (F 11440)  Chemical Structure
  60. GC30910 Eucalyptol (1,8-Cineole) A bicyclic monoterpene with diverse biological activities Eucalyptol (1,8-Cineole)  Chemical Structure
  61. GC31032 F-15599 F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist, with Ki of 3.4 nM. F-15599  Chemical Structure
  62. GC62967 F13714 fumarate F13714 fumarate, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress. F13714 fumarate  Chemical Structure
  63. GC39748 Facinicline hydrochloride Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline hydrochloride  Chemical Structure
  64. GC13109 Fananserin 5-HT2A receptor antagonist Fananserin  Chemical Structure
  65. GC63682 Felcisetrag Felcisetrag (TD-8954) is an orally active, potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties. Felcisetrag  Chemical Structure
  66. GC14512 Fenspiride HCl α adrenergic and H1 histamine receptor antagonist Fenspiride HCl  Chemical Structure
  67. GC32439 Ferulic acid sodium (Sodium ferulate) Ferulic acid sodium (Sodium ferulate) is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. Ferulic acid sodium (Sodium ferulate)  Chemical Structure
  68. GC31011 FK1052 hydrochloride FK1052 hydrochloride ((±)-FK1052) is the racemate of Fabesetron hydrochloride, which is a potent 5-HT3 and 5-HT4 receptor dual antagonist. FK1052 hydrochloride  Chemical Structure
  69. GC60846 Flesinoxan Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan  Chemical Structure
  70. GC11100 Flibanserin full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A. Flibanserin  Chemical Structure
  71. GC68364 Flibanserin-d4-1 Flibanserin-d4-1  Chemical Structure
  72. GC12535 Flopropione 5-HT receptor antagonist Flopropione  Chemical Structure
  73. GC38912 Flumexadol Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A receptor. Flumexadol  Chemical Structure
  74. GC11709 Fluoxetine HCl Serotonin reuptake inhibitor,selective Fluoxetine HCl  Chemical Structure
  75. GC13092 Fluvoxamine Selective serotonin reuptake inhibitor Fluvoxamine  Chemical Structure
  76. GC15025 Fluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant Fluvoxamine maleate  Chemical Structure
  77. GC25434 Frovatriptan Succinate Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors. Frovatriptan Succinate  Chemical Structure
  78. GC38781 Frovatriptan succinate hydrate An agonist of 5-HT1B and 5-HT1D receptors Frovatriptan succinate hydrate  Chemical Structure
  79. GC38227 Gamma-Mangostin A xanthone with diverse biological activities Gamma-Mangostin  Chemical Structure
  80. GC38529 Geissoschizine methyl ether Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether  Chemical Structure
  81. GC11624 GR 113808 5-HT4 receptor antagonist GR 113808  Chemical Structure
  82. GC15248 GR 125487 sulfamate 5-HT4 receptor antagonist GR 125487 sulfamate  Chemical Structure
  83. GC61464 GR 125743 GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively. GR 125743  Chemical Structure
  84. GC17140 GR 127935 hydrochloride 5-HT1B/1D receptor antagonist GR 127935 hydrochloride  Chemical Structure
  85. GC14373 GR 46611 GR 46611 is a 5-HT1D receptor agonist. GR 46611 can be used in the research of bladder hyperactivity, leukemia. GR 46611  Chemical Structure
  86. GC17524 GR 55562 dihydrochloride 5-HT1B (5-HT1Dβ) silent antagonist GR 55562 dihydrochloride  Chemical Structure
  87. GC12398 Granisetron Granisetron  Chemical Structure
  88. GC16029 Granisetron HCl Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Granisetron HCl  Chemical Structure
  89. GC19176 GSK163090 GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively. GSK163090  Chemical Structure
  90. GC30762 Harmine (Telepathine) A unique regulator of PPARγ expression Harmine (Telepathine)  Chemical Structure
  91. GC38413 Harmine hydrochloride Harmine hydrochloride  Chemical Structure
  92. GC60915 Hydroxy ziprasidone Hydroxy ziprasidone is an impurity of Ziprasidone. Hydroxy ziprasidone  Chemical Structure
  93. GC36291 Idalopirdine A 5-HT6 receptor antagonist Idalopirdine  Chemical Structure
  94. GC63015 Iferanserin Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin  Chemical Structure
  95. GC15463 Iloperidone Dopamine (D2) and serotonin (5HT2) receptor antagonist Iloperidone  Chemical Structure
  96. GC10799 Iloperidone hydrochloride D(2)/5-HT(2) receptor antagonistis Iloperidone hydrochloride  Chemical Structure
  97. GC12885 Imipramine (hydrochloride) serotonin and norepinephrine transporters inhibitor Imipramine (hydrochloride)  Chemical Structure
  98. GC14093 Indatraline hydrochloride Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) Indatraline hydrochloride  Chemical Structure
  99. GC61565 Indophagolin Indophagolin is a potent, indoline-containing autophagy inhibitor (IC50=140 nM). Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 μM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7. Indophagolin  Chemical Structure
  100. GC60938 Iprindole Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT. Iprindole  Chemical Structure
  101. GC13133 Ipsapirone 5-HT1A receptor agonist Ipsapirone  Chemical Structure

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