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Home >> Signaling Pathways >> Neuroscience >> Pain Research

Pain Research

Products for  Pain Research

  1. Cat.No. Product Name Information
  2. GC49097 α-Conotoxin AuIB (trifluoroacetate salt) A conotoxin and an antagonist of α3β4 subunit-containing nAChRs α-Conotoxin AuIB (trifluoroacetate salt) Chemical Structure
  3. GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene Chemical Structure
  4. GC45234 β-Endorphin (1-27) (human) (trifluoroacetate salt) β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). β-Endorphin (1-27) (human) (trifluoroacetate salt) Chemical Structure
  5. GC49865 γ-D-Glutamylglycine (trifluoroacetate salt) An excitatory amino acid antagonist γ-D-Glutamylglycine (trifluoroacetate salt) Chemical Structure
  6. GC46288 (±)-Epibatidine (hydrochloride) An agonist of α4β2 subunit-containing nAChRs (±)-Epibatidine (hydrochloride) Chemical Structure
  7. GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen (±)-Ibuprofen-d3 (sodium salt) Chemical Structure
  8. GC41685 (±)-WIN 55,212 (mesylate) (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. (±)-WIN 55,212 (mesylate) Chemical Structure
  9. GC41191 (±)13(14)-EpDPA Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA Chemical Structure
  10. GC41203 (±)7(8)-EpDPA Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA Chemical Structure
  11. GC18343 (-)-CP 55,940 (-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively. (-)-CP 55,940 Chemical Structure
  12. GC40594 (R)-AM1241 (R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor (Kis = 15 and 5,000 nM, respectively, in a membrane assay using human receptors). (R)-AM1241 Chemical Structure
  13. GC40595 (S)-AM1241 (S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors). (S)-AM1241 Chemical Structure
  14. GC46366 1,2,3,4-Tetrahydro-β-carboline A serotonin reuptake inhibitor and metabolite of tryptamine 1,2,3,4-Tetrahydro-β-carboline Chemical Structure
  15. GC49861 1-Carboxycyclohexaneacetic Acid A potential impurity in commercial preparations of gabapentin 1-Carboxycyclohexaneacetic Acid Chemical Structure
  16. GC46050 1-Deoxysphingosine (m18:1(4E)) An atypical sphingolipid 1-Deoxysphingosine (m18:1(4E)) Chemical Structure
  17. GC18783 13,14-dihydro-15-keto Prostaglandin E1 13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. 13,14-dihydro-15-keto Prostaglandin E1 Chemical Structure
  18. GC42258 3-Cysteinylacetaminophen (trifluoroacetate salt) An acetaminophen-protein adduct 3-Cysteinylacetaminophen (trifluoroacetate salt) Chemical Structure
  19. GC49752 4,5-Desisopropylidene Topiramate An inactive metabolite of topiramate 4,5-Desisopropylidene Topiramate Chemical Structure
  20. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam Chemical Structure
  21. GC49119 5-hydroxy Flunixin A metabolite of flunixin 5-hydroxy Flunixin Chemical Structure
  22. GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine. 5-hydroxy-6-methoxy (S)-Duloxetine Chemical Structure
  23. GC42580 6-hydroxy Chlorzoxazone

    6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.

     6-hydroxy Chlorzoxazone Chemical Structure
  24. GC48880 7-Methoxyflavone A flavone with diverse biological activities 7-Methoxyflavone Chemical Structure
  25. GC40759 8-methyl Nonanoic Acid

    Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family.

     8-methyl Nonanoic Acid Chemical Structure
  26. GC42693 Acetaminophen Glucuronide (sodium salt) Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen. Acetaminophen Glucuronide (sodium salt) Chemical Structure
  27. GC42694 Acetaminophen sulfate (potassium salt) Acetaminophen sulfate is a metabolite of acetaminophen. Acetaminophen sulfate (potassium salt) Chemical Structure
  28. GC46781 Acetaminophen-d4 A Certified Reference Material Acetaminophen-d4 Chemical Structure
  29. GC42704 Acetyl β-Endorphin (human) (trifluoroacetate salt) Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). Acetyl β-Endorphin (human) (trifluoroacetate salt) Chemical Structure
  30. GC46789 Acetyl-L-carnitine-d3 (chloride) An internal standard for the quantification of L-acetylcarnitine Acetyl-L-carnitine-d3 (chloride) Chemical Structure
  31. GC49639 Akuammine An indole alkaloid with analgesic activity Akuammine Chemical Structure
  32. GC46826 Alclofenac An NSAID Alclofenac Chemical Structure
  33. GC42809 Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)

    Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.

     Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt) Chemical Structure
  34. GC46856 Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)

    An endogenous angiotensin II fragment

     Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt) Chemical Structure
  35. GC46858 Anthirine An alkaloid with analgesic activity Anthirine Chemical Structure
  36. GC49473 ARA 290 (acetate) A derivative of EPO ARA 290 (acetate) Chemical Structure
  37. GC46877 Arachidonoyl Glycine-d8 An internal standard for the quantification of arachidonoyl glycine Arachidonoyl Glycine-d8 Chemical Structure
  38. GC42865 AT-121 AT-121 is a dual μ-opioid and nociceptin receptor partial agonist (Kis = 16.49 and 3.67 nM, respectively). AT-121 Chemical Structure
  39. GC42885 AX 048 The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 Chemical Structure
  40. GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide and MRGPRX1 agonist BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  41. GC52407 BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  42. GC49019 BAN ORL 24 (hydrochloride) A nociceptin receptor antagonist BAN ORL 24 (hydrochloride) Chemical Structure
  43. GC39344 BAY-1797 A P2X4receptor antagonist BAY-1797 Chemical Structure
  44. GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen Chemical Structure
  45. GC49300 BIM-46187 (hydrochloride) An inhibitor of heterotrimeric G-protein signaling BIM-46187 (hydrochloride) Chemical Structure
  46. GC52145 Bradykinin (human, mouse, rat, bovine) (acetate) Bradykinin (human, mouse, rat, bovine) (acetate) Chemical Structure
  47. GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator Bradykinin (trifluoroacetate salt) Chemical Structure
  48. GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin Bradykinin Fragment (1-5) (trifluoroacetate salt) Chemical Structure
  49. GC42990 Bupivacaine Bupivacaine is a sodium channel blocker and local anesthetic. Bupivacaine Chemical Structure
  50. GC46959 Bupivacaine-d9 An internal standard for the quantification of bupivacaine Bupivacaine-d9 Chemical Structure
  51. GC49761 Capsaicin-d3 Capsaicin-d3 ((E)-Capsaicin-d3) is the deuterium labeled Capsaicin. Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects. Capsaicin-d3 Chemical Structure
  52. GC49433 Capsiate A capsaicin analog with diverse biological activities Capsiate Chemical Structure
  53. GC43155 CAY10448 Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. CAY10448 Chemical Structure
  54. GC43171 CAY10568 Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. CAY10568 Chemical Structure
  55. GC49226 CAY10787 An oxysterol and a negative allosteric modulator of GABAA receptors CAY10787 Chemical Structure
  56. GC18695 CB-86 CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively. CB-86 Chemical Structure
  57. GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt) A CGRP receptor antagonist CGRP (8-37) (mouse, rat) (trifluoroacetate salt) Chemical Structure
  58. GC49191 Chlorzoxazone-d3 An internal standard for the quantification of chlorzoxazone Chlorzoxazone-d3 Chemical Structure
  59. GC18369 Cimicoxib A selective inhibitor of COX-2 Cimicoxib Chemical Structure
  60. GC18728 CJ-13610 CJ-13610 is an inhibitor of 5-lipoxygenase (5-LO) that inhibits 5-LO product formation in human polymorphonuclear leukocytes (PMNLs) challenged with A23187 in vitro (IC50 = 70 nM). CJ-13610 Chemical Structure
  61. GC52243 Corynantheidine An alkaloid with antinociceptive activity Corynantheidine Chemical Structure
  62. GC43327 CTAP (trifluoroacetate salt) CTAP is a water soluble, cyclic octapeptide which acts as a receptor antagonist that is selective for the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM). CTAP (trifluoroacetate salt) Chemical Structure
  63. GC52077 CTP354 CTP354 is the deuterium labeled L-838417. CTP354 Chemical Structure
  64. GC43373 D-Amino Acid Oxidase Inhibitor D-Amino acid oxidase inhibitor is an inhibitor of D-amino acid oxidase (DAAO) with IC50 values of 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively. D-Amino Acid Oxidase Inhibitor Chemical Structure
  65. GC43383 DBO-83 DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities. DBO-83 Chemical Structure
  66. GC43391 Decanoic Acid (sodium salt) Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. Decanoic Acid (sodium salt) Chemical Structure
  67. GC45815 Decanoic Acid-d19 An internal standard for the quantification of decanoic acid Decanoic Acid-d19 Chemical Structure
  68. GC46127 Decanoic Acid-d2 An internal standard for the quantification of decanoic acid Decanoic Acid-d2 Chemical Structure
  69. GC45722 Decanoic Acid-d3 An internal standard for the quantification of decanoic acid Decanoic Acid-d3 Chemical Structure
  70. GC49338 Deltorphin II (trifluoroacetate salt) A peptide agonist of δ2-opioid receptors Deltorphin II (trifluoroacetate salt) Chemical Structure
  71. GC47188 Dermorphin (acetate) An opioid peptide Dermorphin (acetate) Chemical Structure
  72. GC49858 Desipramine-d4 (hydrochloride) An internal standard for the quantification of desipramine Desipramine-d4 (hydrochloride) Chemical Structure
  73. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide Chemical Structure
  74. GC43446 Diclofenac ethyl ester An esterified form of diclofenac Diclofenac ethyl ester Chemical Structure
  75. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  76. GC49304 Difelikefalin (trifluoroacetate salt) A κ-opioid receptor agonist Difelikefalin (trifluoroacetate salt) Chemical Structure
  77. GC49829 DL-threo-β-Hydroxyaspartic Acid An EAAT inhibitor DL-threo-β-Hydroxyaspartic Acid Chemical Structure
  78. GC47314 Ethopropazine (hydrochloride) A BChE inhibitor Ethopropazine (hydrochloride) Chemical Structure
  79. GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate Etofenamate-d4 Chemical Structure
  80. GC47336 Fenobam (hydrate) A noncompetitive antagonist and inverse agonist of mGluR5 Fenobam (hydrate) Chemical Structure
  81. GC49747 Flunixin-d3 An internal standard for the quantification of flunixin Flunixin-d3 Chemical Structure
  82. GC45761 Flupirtine-d4 (hydrochloride) An internal standard for the quantification of flupirtine Flupirtine-d4 (hydrochloride) Chemical Structure
  83. GC47388 Gabapentin-d4 An internal standard for the quantification of gabapentin Gabapentin-d4 Chemical Structure
  84. GC49154 Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  85. GC48326 Galanin (human) (acetate) A neuropeptide and GAL receptor agonist Galanin (human) (acetate) Chemical Structure
  86. GC43724 Galanin (rat, mouse) (trifluoroacetate salt)

    Galanin is a neuropeptide with diverse biological activities.

     Galanin (rat, mouse) (trifluoroacetate salt) Chemical Structure
  87. GC43738 GAT211 GAT211 is an agonist and positive allosteric modulator (PAM) of cannabinoid receptor 1 (CB1) and a racemic mixture of GAT228 and GAT229, which have enantiomer-specific activities. GAT211 Chemical Structure
  88. GC43774 Glycerophospho-N-Arachidonoyl Ethanolamine N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. Glycerophospho-N-Arachidonoyl Ethanolamine Chemical Structure
  89. GC49509 Glycyl-L-Glutamine (hydrate) A dipeptide fragment of β-endorphin Glycyl-L-Glutamine (hydrate) Chemical Structure
  90. GC18181 GW 405833 GW 405833 is a partial agonist of the cannabinoid CB2 receptor (EC50 = 0.65 nM). GW 405833 Chemical Structure
  91. GC49882 Hemokinin 1 (human) (trifluoroacetate salt) A peptide agonist of NK1 receptors Hemokinin 1 (human) (trifluoroacetate salt) Chemical Structure
  92. GC48453 Hodgkinsine An alkaloid with analgesic activity Hodgkinsine Chemical Structure
  93. GC48454 Hodgkinsine B An alkaloid with analgesic activity Hodgkinsine B Chemical Structure
  94. GC49559 Hydroxymethyl Tolperisone (hydrochloride) A metabolite of tolperisone Hydroxymethyl Tolperisone (hydrochloride) Chemical Structure
  95. GC43891 IDFP The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). IDFP Chemical Structure
  96. GC52154 Inflammasome Inhibitor 4b Inflammasome Inhibitor 4b Chemical Structure
  97. GC43906 Iperoxo (iodide) Iperoxo (iodide) is a potent superagonist of muscarinic acetylcholine receptor (mAChR). Iperoxo (iodide) Chemical Structure
  98. GC47528 Ketorolac (calcium salt) Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac (calcium salt) Chemical Structure
  99. GC52020 Lamotrigine-d3 An internal standard for the quantification of lamotrigine Lamotrigine-d3 Chemical Structure
  100. GC49608 Larixyl Acetate Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl Acetate Chemical Structure
  101. GC49720 Leu-Enkephalin (trifluoroacetate salt) A neuropeptide and δ- and µ-opioid receptor agonist Leu-Enkephalin (trifluoroacetate salt) Chemical Structure

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