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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> Chk

Chk

Chk (Csk homologous kinase)

Products for  Chk

  1. Cat.No. Product Name Information
  2. GC10546 AZD7762 Checkpoint kinase inhibitor,ATP competitive AZD7762 Chemical Structure
  3. GC11648 BML-277

    BML-277, C 3742, Checkpoint Kinase 2 Inhibitor II

     Chk2 inhibitor,potent and highly selective BML-277 Chemical Structure
  4. GC18053 CCT241533 A selective Chk2 inhibitor CCT241533 Chemical Structure
  5. GC17105 CCT241533 hydrochloride A selective Chk2 inhibitor CCT241533 hydrochloride Chemical Structure
  6. GC14772 CCT244747 Potent and selective CHK1 inhibitor CCT244747 Chemical Structure
  7. GC15739 CHIR-124 Chk1 inhibitor,novel and potent CHIR-124 Chemical Structure
  8. GC15741 LY2603618

    IC-83, Rabusertib

     LY2603618 (LY2603618) is a potent and selective inhibitor of Chk1 with an IC50 of 7 nM. LY2603618 Chemical Structure
  9. GC15663 LY2606368

    Prexasertib

     LY2606368, an ATP-competitive CHK1 inhibitor, is currently in the clinical stage with a Ki of 0.9 nM and an IC50 of <1 nM. LY2606368 inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). LY2606368 Chemical Structure
  10. GC16374 MK-8776(SCH-900776)

    MK-8776

     MK-8776(SCH-900776) (MK-8776) is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with an IC50 of 3 nM. MK-8776(SCH-900776) shows 50- and 500-fold selectivity over CDK2 and Chk2, respectively. MK-8776(SCH-900776) Chemical Structure
  11. GC13448 NSC 109555 ditosylate Chk2 inhibitor,ATP-competitive NSC 109555 ditosylate Chemical Structure
  12. GC14234 PF-477736

    PF 00477736

     Chk1 inhibitor PF-477736 Chemical Structure
  13. GC11022 SB 218078 checkpoint kinase 1 (Chk1) inhibitor SB 218078 Chemical Structure
  14. GC10793 TCS 2312 checkpoint kinase 1 (chk1) inhibitor TCS 2312 Chemical Structure

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