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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> G1

G1

Products for  G1

  1. Cat.No. Product Name Information
  2. GC70332 (+)-Erinacin A (+)-Erinacin A is an anticancer compound that can be isolated from the mushroom Hericium erinaceum. (+)-Erinacin A Chemical Structure
  3. GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin. 2-deoxy-Artemisinin Chemical Structure
  4. GC45354 4β-Hydroxywithanolide E

    NSC 212509

     A withanolide with anti-inflammatory and anticancer activities 4β-Hydroxywithanolide E Chemical Structure
  5. GC42586 6α-hydroxy Paclitaxel

    6α-hydroxy Taxol

     6α-hydroxy Paclitaxel is a primary metabolite of the anticancer compound paclitaxel, produced by the action of the cytochrome P450 isoform CYP2C8. 6α-hydroxy Paclitaxel Chemical Structure
  6. GC63958 6α-Hydroxy Paclitaxel-d5 6α-Hydroxy Paclitaxel-d5 is the deuterium labeled 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer. 6α-Hydroxy Paclitaxel-d5 Chemical Structure
  7. GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid all-trans-13,14-Dihydroretinol Chemical Structure
  8. GC18539 all-trans-4-hydroxy Retinoic Acid

    4-OH-atRA, 4-hydroxy RA

     all-trans-4-hydroxy Retinoic acid is a metabolite of all-trans retinoic acid formed by the cytochrome P450 (CYP) isoforms CYP26A1, B1, and C1. all-trans-4-hydroxy Retinoic Acid Chemical Structure
  9. GC45385 Ara-G

    ara-Guanosine, Guanine Arabinoside, NSC 76352

       Ara-G Chemical Structure
  10. GC46882 Artemisinin-d3

    Qinghaosu-d3; NSC 369397-d3

     An internal standard for the quantification of artemisinin Artemisinin-d3 Chemical Structure
  11. GC49042 Benastatin A A bacterial metabolite with diverse biological activities Benastatin A Chemical Structure
  12. GC40009 Bostrycin

    Rhodosporin

     Bostrycin is an anthraquinone originally isolated from B. Bostrycin Chemical Structure
  13. GC40708 C2 L-erythro Ceramide (d18:1/2:0)

    L-erythro Cer(d18:1/2:0), L-erythro Ceramide (d18:1/2:0), N-acetyl-L-erythro-Sphingosine

     C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides. C2 L-erythro Ceramide (d18:1/2:0) Chemical Structure
  14. GC40709 C2 L-threo Ceramide (d18:1/2:0)

    L-threo Cer(d18:1/2:0), L-threo Ceramide (d18:1/2:0), N-acetyl-L-threo-Sphingosine

     C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C2 L-threo Ceramide (d18:1/2:0) Chemical Structure
  15. GC40795 CAY10503 CAY10503 is a proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase. CAY10503 Chemical Structure
  16. GC52245 CAY10792 An anticancer agent CAY10792 Chemical Structure
  17. GC43217 CDK/CRK Inhibitor

    Cdk7 Inhibitor IV, Cyclin-dependent kinase 7 Inhibitor IV, Cyclin-dependent kinase/CDK-related kinase Inhibitor, RGB-286147

     CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM in vitro. CDK/CRK Inhibitor Chemical Structure
  18. GC43265 Chromomycin A2

    Aburamycin A, CMA2, NSC 131187

     Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities. Chromomycin A2 Chemical Structure
  19. GC45764 Ciclopirox-d11 (sodium salt)

    HOE 296b-d11

     A neuropeptide with diverse biological activities Ciclopirox-d11 (sodium salt) Chemical Structure
  20. GC43321 CPTH6 (hydrobromide) CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. CPTH6 (hydrobromide) Chemical Structure
  21. GC43354 Cysmethynil

    Icmt Inhibitor

     Post-translational protein prenylation is a 3-step process that occurs at the C-terminus of a number of proteins involved in cell growth control and oncogenesis. Cysmethynil Chemical Structure
  22. GC45800 Cytarabine-13C3

    Ara-C-13C3, 1-β-D-Arabinofuranosylcytosine-13C3

     A neuropeptide with diverse biological activities Cytarabine-13C3 Chemical Structure
  23. GC40296 D-erythro-MAPP

    (1S,2RDerythro2Nmyristoylamino)1phenyl1propanol

     D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). D-erythro-MAPP Chemical Structure
  24. GC43448 Didymin Didymin is a flavonoid that has been found in citrus fruits with diverse biological activities. Didymin Chemical Structure
  25. GC40751 Dihydroartemisinic Acid Dihydroartemisinic acid is a biosynthetic precursor to the antimalarial agent artemisinin and an intermediate in the synthesis of artemisinin from artemisinic acid . Dihydroartemisinic Acid Chemical Structure
  26. GC18693 Fascaplysin (chloride)

    NSC 622398

     Fascaplysin (chloride) is an antimicrobial and cytotoxic red pigment, that can come from the marine sponge (Fascaplysin (chloride)opsis sp. Fascaplysin (chloride) Chemical Structure
  27. GC49344 Fisetin-d5 An internal standard for the quantification of fisetin Fisetin-d5 Chemical Structure
  28. GC49089 FR900359

    UBO-QIC

     FR900359 is an inhibitor of G proteins Gαq, Gα11, and Gα14 with IC50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata FR900359 Chemical Structure
  29. GC48387 Inostamycin A A bacterial metabolite with anticancer activity Inostamycin A Chemical Structure
  30. GC52472 Inostamycin A (sodium salt)

    Inostamycin

     A bacterial metabolite with anticancer activity Inostamycin A (sodium salt) Chemical Structure
  31. GC92037 JQKD82 (hydrochloride)

    JADA82; PCK82

     JQKD82 is a prodrug form of KDM5-C49, an inhibitor of Jumonji AT-rich interactive domain 1A (JARID1A), also known as lysine-specific demethylase 5A (KDM5A). JQKD82 (hydrochloride) Chemical Structure
  32. GC43995 Kazusamycin B

    CL 1957E, Hydroxyleptomycin A, PD 124895

     Kazusamycin B is a bacterial metabolite originally isolated from Streptomyces. Kazusamycin B Chemical Structure
  33. GC47619 Menaquinone 4-d7

    MK-4-d7, Vitamin K2(20)-d7

     An internal standard for the quantification of menaquinone 4 Menaquinone 4-d7 Chemical Structure
  34. GC44181 Methylcarbamyl PAF C-8 Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16. Methylcarbamyl PAF C-8 Chemical Structure
  35. GC45523 Nemorosone   Nemorosone Chemical Structure
  36. GC44475 NVP-BEZ235 (hydrochloride)

    Dactolisib

     NVP-BEZ235 is a potent dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anticancer agents when used in in vivo combination studies. NVP-BEZ235 (hydrochloride) Chemical Structure
  37. GC45538 Oxychlororaphine

    phenazine-1-carboxamide

       Oxychlororaphine Chemical Structure
  38. GA23337 Oxythiamine . HCl Thiamine antagonist and inhibitor of saccharomyces cerevisiae transketolase. RaÏs et al. indicated that oxythiamine inhibits the growth of Ehrlich's tumor cells. Oxythiamine . HCl Chemical Structure
  39. GC45758 Paclitaxel octadecanedioate

    1,18-Octadecanedioic Acid-Paclitaxel, ODDA-PTX, PTX-FA18

     A prodrug form of paclitaxel Paclitaxel octadecanedioate Chemical Structure
  40. GC47853 Paclitaxel-d5 An internal standard for the quantification of paclitaxel Paclitaxel-d5 Chemical Structure
  41. GC18353 Prostaglandin A2

    Medullin

     A naturally occurring prostaglandin with antiviral/antitumor activity Prostaglandin A2 Chemical Structure
  42. GC48019 Quercetin (hydrate) A flavonoid with diverse biological activities Quercetin (hydrate) Chemical Structure
  43. GC48020 Quercetin-d3 (hydrate) A neuropeptide with diverse biological activities Quercetin-d3 (hydrate) Chemical Structure
  44. GC44846 RK-682 (calcium salt)

    CI-010, TAN 1364B

     Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. RK-682 (calcium salt) Chemical Structure
  45. GC18852 S14161 D-Cyclins regulate the cell cycle by acting in a complex with cyclin dependent kinases (CDKs) to promote phosphorylation of the retinoblastoma protein and initiate cellular progression from the G1 to the S phase. S14161 Chemical Structure
  46. GC49674 Schizandrin

    (+)-Schizandrin, Schizandrol A

     Schizandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schizandrin Chemical Structure
  47. GC48076 Sesquicillin A

    Sesquicillin

     A fungal metabolite Sesquicillin A Chemical Structure
  48. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities Sinigrin (hydrate) Chemical Structure
  49. GC45829 Troglitazone-d4

    CS-045-d4

     A neuropeptide with diverse biological activities Troglitazone-d4 Chemical Structure
  50. GC48659 Umbelliprenin

    7-Farnesyloxycoumarin

     A prenylated coumarin with diverse biological activities Umbelliprenin Chemical Structure
  51. GC40044 Zymostenol

    Δ8-Cholesterol

     Zymostenol is a late-stage precursor in the biosynthesis of cholesterol. Zymostenol Chemical Structure

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