Mps1
MPS1 (monopolar spindle 1 kinase) is a crucial part of the spindle assembly checkpoint. It facilitates the formation of C-MAD2 (closed MAD2) conformer and the MCC (mitotic checkpoint complex) assembly, and involved in the tumor growth.
Products for Mps1
- Cat.No. Product Name Information
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GC15283
AZ3146
AZ 3146; AZ-3146
Mps1 inhibitor,potent and selective -
GC19058
BAY1217389
BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
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GC32846
BOS-172722
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer.
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GC33213
CCT251455
CCT251455 is a potent and selective mitotic kinase monopolar spindle 1 (MPS1) inhibitor with an IC50 of 3 nM.
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GC34073
Empesertib (BAY 1161909)
BAY 1161909
Empesertib (BAY 1161909) (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM. -
GC10083
MPI-0479605
Mps1 inhibitor,selective and ATP competitive
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GC11292
Mps1-IN-1
Monopolar Spindle 1 Kinase Inhibitor 1, Mps1 Kinase Inhibitor 1
Mps1 kinase inhibitor
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GC50110
Mps1-IN-1 dihydrochloride
Selective Mps1 kinase inhibitor
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GC15745
Mps1-IN-2
Mps1 kinase inhibitor
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GC36651
Mps1-IN-3
Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM.
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GC65339
Mps1-IN-3 hydrochloride
Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model.
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GC36752
NMS-P715
An Mps1/TTK inhibitor
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GC13727
TC Mps1 12
Mps1 inhibitor