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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> Proteolysis

Proteolysis

Products for  Proteolysis

  1. Cat.No. Product Name Information
  2. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

    (±)214,15EG

     2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol Chemical Structure
  3. GC40145 (S)-Laudanosine

    (+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045

     (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine Chemical Structure
  4. GC49390 13C6-4-Nitroaniline

    13C6-p-Nitroaniline

     An internal standard for the quantification of 4-nitroaniline 13C6-4-Nitroaniline Chemical Structure
  5. GC18359 4-Epianhydrochlortetracycline (hydrochloride) 4-Epianhydrochlortetracycline is a derivative of tetracycline . 4-Epianhydrochlortetracycline (hydrochloride) Chemical Structure
  6. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone

    (±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL

     An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone Chemical Structure
  7. GC41423 5-trans Prostaglandin E2

    transDinoprostone, 5,6trans PGE2

     5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2 Chemical Structure
  8. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxycholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  9. GC42665 AAF-CMK (trifluoroacetate salt)

    NAlaAlaPheCMK, Tripeptidyl Peptidase Inhibitor II

     Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK (trifluoroacetate salt) Chemical Structure
  10. GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Chemical Structure
  11. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  12. GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  13. GA20494 Ac-Asp-Glu-Val-Asp-pNA

    Ac-Asp-Glu-Val-Asp-pNA

     The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA Chemical Structure
  14. GC48470 Ac-DEVD-CHO (trifluoroacetate salt)

    N-Ac-Asp-Glu-Val-Asp-CHO

     A dual caspase3/caspase7 inhibitor Ac-DEVD-CHO (trifluoroacetate salt) Chemical Structure
  15. GC42689 Ac-DNLD-AMC

    Ac-Asp-Asn-Leu-Asp-MCA, N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin, Caspase-3 Substrate

     Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-DNLD-AMC Chemical Structure
  16. GC49704 Ac-FLTD-CMK (trifluoroacetate salt)

    Ac-Phe-Leu-Thr-Asp-CMK

     An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt) Chemical Structure
  17. GC18226 Ac-LEHD-AMC (trifluoroacetate salt)

    Ac-Leu-Glu-His-Asp-AMC, Caspase-9 Substrate

     Ac-LEHD-AMC (trifluoroacetate salt) is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Ac-LEHD-AMC (trifluoroacetate salt) Chemical Structure
  18. GC40556 Ac-LETD-AFC

    NAcetylLeuGluThrAsp7amino4Trifluoromethylcoumarin, Caspase8 Substrate (Fluorogenic)

     Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Ac-LETD-AFC Chemical Structure
  19. GC13400 Ac-VDVAD-AFC

    N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin Caspase-2 Substrate (Fluorogenic)

     Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer. Ac-VDVAD-AFC Chemical Structure
  20. GC52372 Ac-VDVAD-AFC (trifluoroacetate salt)

    N-Acetyl-Val-Asp-Val-Ala-Asp-AFC, N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-2 Substrate (Fluorogenic)

     A fluorogenic substrate for caspase-2 Ac-VDVAD-AFC (trifluoroacetate salt) Chemical Structure
  21. GC48974 Ac-VEID-AMC (ammonium acetate salt)

    NAcetylValGluIleAsp7amido4Methylcoumarin, Caspase6 Substrate (Fluorogenic)

     A caspase-6 fluorogenic substrate Ac-VEID-AMC (ammonium acetate salt) Chemical Structure
  22. GC18021 Ac-YVAD-CHO

    Caspase-1 Inhibitor I, L 709049, N-Ac-Tyr-Val-Ala-Asp-CHO

     Selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1) Ac-YVAD-CHO Chemical Structure
  23. GC42721 Ac-YVAD-CMK

    N-Ac-Tyr-Val-Ala-Asp-CMK

     Ac-YVAD-CMK is a selective irreversible inhibitor of caspase-1 (Ki=0.8nM), which can prevent the proinflammatory cytokine IL-1β activation. Ac-YVAD-CMK can reduce the inflammatory response and induce a long-lasting neuroprotective effect. Ac-YVAD-CMK Chemical Structure
  24. GC42788 Aminopeptidase N Inhibitor Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). Aminopeptidase N Inhibitor Chemical Structure
  25. GC46867 Apremilast-d5

    APR-d5

     An internal standard for the quantification of apremilast Apremilast-d5 Chemical Structure
  26. GC46878 Aranciamycin

    NSC 369226

     A fungal metabolite with diverse biological activities Aranciamycin Chemical Structure
  27. GC46895 Aurintricarboxylic Acid (ammonium salt)

    ATA

     A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  28. GC46937 Boc-Glu-OBzl An amino acid-containing building block Boc-Glu-OBzl Chemical Structure
  29. GC45394 Bz-IEGR-pNA (acetate)

    Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate

       Bz-IEGR-pNA (acetate) Chemical Structure
  30. GC18315 Calpain Inhibitor VI

    SJA 6017

     Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM). Calpain Inhibitor VI Chemical Structure
  31. GC43150 CAY10406 CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. CAY10406 Chemical Structure
  32. GC43154 CAY10443

    (S)Indan1yl 3,4dichlorobenzylcarbamate

     Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. CAY10443 Chemical Structure
  33. GC47079 Chloramine-T (hydrate) A common reagent Chloramine-T (hydrate) Chemical Structure
  34. GC52360 Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt)

    Suc-GGF-pNA, Suc-Gly-Gly-Phe-pNA, Suc-Gly-Gly-Phe-p-Nitroanilide

     A colorimetric chymotrypsin substrate Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt) Chemical Structure
  35. GC18421 Dabcyl-YVADAPV-EDANS

    Dabcyl-ICE-EDANS

     Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Dabcyl-YVADAPV-EDANS Chemical Structure
  36. GC43371 Dabigatran Acyl-β-D-Glucuronide

    β-1-O-Acylglucuronide

    Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.

     Dabigatran Acyl-β-D-Glucuronide Chemical Structure
  37. GC49684 Dabigatran-13C-d3

    BIBR 953-13C,d3; BIBR 953ZW-13C,d3

     An internal standard for the quantification of dabigatran Dabigatran-13C-d3 Chemical Structure
  38. GC49682 Dabigatran-d3

    BIBR 953-d3; BIBR 953ZW-d3

     An internal standard for the quantification of dabigatran Dabigatran-d3 Chemical Structure
  39. GC43545 Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

    Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2, Matrix Metalloproteinase-1/Matrix Metalloproteinase-9 Fluorogenic Substrate, MMP-1/MMP-9 Fluorogenic Substrate

     Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 Chemical Structure
  40. GC43546 Dnp-PLALWAR (trifluoroacetate salt)

    Matrix Metalloproteinase-1 Fluorogenic Substrate I, MMP-1 Fluorogenic Substrate I

     Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8. Dnp-PLALWAR (trifluoroacetate salt) Chemical Structure
  41. GC43547 Dnp-PLAYWAR (trifluoroacetate salt)

    Dnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH, Matrix Metalloproteinase-8/Matrix Metalloproteinase-26 Fluorogenic Substrate, MMP-8/MMP-26 Fluorogenic Substrate

     Dnp-PLAYWAR is a fluorogenic substrate for matrix metalloproteinase-8 (MMP-8) and MMP-26. Dnp-PLAYWAR (trifluoroacetate salt) Chemical Structure
  42. GC43550 Dnp-PLGMWSR (trifluoroacetate salt)

    Dnp-Pro-Leu-Gly-Met-Trp-Ser-Arg-OH, Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Fluorogenic Substrate I, MMP-2/MMP-9 Fluorogenic Substrate I

     Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. Dnp-PLGMWSR (trifluoroacetate salt) Chemical Structure
  43. GC43552 Dnp-RPLALWRS (trifluoroacetate salt)

    Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH, Matrix Metalloproteinase-7 Fluorogenic Substrate, MMP-7 Fluorogenic Substrate

     Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). Dnp-RPLALWRS (trifluoroacetate salt) Chemical Structure
  44. GC43614 Enteropeptidase Fluorogenic Substrate Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase Fluorogenic Substrate Chemical Structure
  45. GC48995 Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt) A fluorogenic substrate of enteropeptidase Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt) Chemical Structure
  46. GC49322 GGACK (hydrochloride)

    Glu-Gly-Arg-Chloromethyl Ketone, Glu-Gly-Arg-CH2Cl

     A uPA and factor Xa inhibitor GGACK (hydrochloride) Chemical Structure
  47. GC49437 Gliotoxin-13C13

    Aspergillin-13C13

     An internal standard for the quantification of gliotoxin Gliotoxin-13C13 Chemical Structure
  48. GC45668 Gly-Arg-AMC (hydrochloride)

    Gly-Arg-7-amino-4-methylcoumarin, GR-AMC, GR-7-amino-4-methylcoumarin

     A fluorogenic substrate for cathepsin C Gly-Arg-AMC (hydrochloride) Chemical Structure
  49. GA22303 H-D-Pro-Phe-Arg-pNA . 2 HCl

    pFR-pNA, Plasma Kallikrein Chromogenic Substrate, D-Pro-Phe-Arg-p-nitroaniline

     pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9. H-D-Pro-Phe-Arg-pNA . 2 HCl Chemical Structure
  50. GC45471 H-Gly-Arg-pNA (hydrochloride)

    Gly-Arg-4-NA, GR-pNA, GR p-nitroanilide

       H-Gly-Arg-pNA (hydrochloride) Chemical Structure
  51. GC49605 H-Gly-Pro-Hyp-OH (acetate)

    H-GP-Hyp-OH, Tripeptide-29

     A peptide DPP-4 inhibitor H-Gly-Pro-Hyp-OH (acetate) Chemical Structure
  52. GC49915 Hexa-D-Arginine (trifluoroacetate salt)

    Furin Inhibitor II, Hexa-D-Arg-NH2, Hexa-D-Arginine amide, D6R-NH2, (D)RRRRRR-NH2

     A furin inhibitor Hexa-D-Arginine (trifluoroacetate salt) Chemical Structure
  53. GC45639 Hexapeptide-11 (acetate)

    FVAPFP, Phe-Val-Ala-Pro-Phe-Pro

     A synthetic hexapeptide Hexapeptide-11 (acetate) Chemical Structure
  54. GC48387 Inostamycin A A bacterial metabolite with anticancer activity Inostamycin A Chemical Structure
  55. GC52472 Inostamycin A (sodium salt)

    Inostamycin

     A bacterial metabolite with anticancer activity Inostamycin A (sodium salt) Chemical Structure
  56. GC49142 Isorhoifolin

    Apigenin-7-O-rutinoside

     A flavonoid glycoside with diverse biological activities Isorhoifolin Chemical Structure
  57. GC43922 Isovaleryl-L-carnitine (chloride)

    CAR 5:0, C5:0 Carnitine, L-Carnitine isovaleryl ester, L-Isovalerylcarnitine

     Isovaleryl-L-carnitine (chloride), a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils. Isovaleryl-L-carnitine (chloride) Chemical Structure
  58. GC18699 JCP174

    7-amino-4-chloro-3-Propoxyisocoumarin

     An inhibitor of palmitoyl protein thioesterase-1 JCP174 Chemical Structure
  59. GC49547 L-Glutamic Acid γ-p-Nitroanilide (hydrate)

    γ-Glu-pNA, Glutamate γ-(4-Nitroanilide), L-GPNA, E-pNA

     A colorimetric substrate for γ-glutamyl transpeptidase L-Glutamic Acid γ-p-Nitroanilide (hydrate) Chemical Structure
  60. GC49205 L-Leu-AMC (hydrochloride)

    Leu-MCA, L-Leucine-7-amido-4-methylcoumarin, 7-L-Leucyl-4-methylcoumarinylamide

     L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leu-AMC (hydrochloride) Chemical Structure
  61. GC49751 Lefamulin

    BC-3781

     Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin Chemical Structure
  62. GC18363 Mca-DEVDAPK(Dnp)-OH

    Caspase-3 Fluorogenic Substrate III, CPP32 Fluorogenic Substrate III, 7-Methoxycoumarin-4-acetyl-DEVDAPK(Dnp)-OH, Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

     Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. Mca-DEVDAPK(Dnp)-OH Chemical Structure
  63. GC44132 Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

    Matrix Metalloproteinase-14 Fluorogenic Substrate I, Mca-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH2, MMP-14 Fluorogenic Substrate I

     Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Chemical Structure
  64. GC44235 MMP Inhibitor I (trifluoroacetate salt)

    Abz-GP-DLeu-DAla-NH-OH, FN 439, Matrix Metalloproteinase Inhibitor I

     MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). MMP Inhibitor I (trifluoroacetate salt) Chemical Structure
  65. GC18218 MMP-3 Inhibitor

    Matrix Metalloproteinase-3 Inhibitor

    MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with a Ki value of 95 nM.

     MMP-3 Inhibitor Chemical Structure
  66. GC40624 MMP-3 Inhibitor VIII

    Matrix Metalloproteinase-3 Inhibitor VIII, Stromelysin-1 Inhibitor VIII

     Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  67. GC18616 MMP-8 Inhibitor I

    Matrix Metalloproteinase-8 Inhibitor I

     MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  68. GC45515 MX1013

    Z-Val-Asp-Fluoromethyl Ketone, Z-VD-FMK

       MX1013 Chemical Structure
  69. GC45667 N-(p-Tosyl)-GPR-pNA (acetate)

    N-(p-Tosyl)-Gly-Pro-Arg-p-Nitroanilide, Tos-Gly-Pro-Arg-pNA

     A colorimetric thrombin substrate N-(p-Tosyl)-GPR-pNA (acetate) Chemical Structure
  70. GC47806 N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)

    N-p-Tosyl-Gly-Pro-Lys-p-nitroanilide

     A colorimetric plasmin substrate N-p-Tosyl-Gly-Pro-Lys-pNA (acetate) Chemical Structure
  71. GC44313 Naphthofluorescein

    CCG 8295

     Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Naphthofluorescein Chemical Structure
  72. GC49186 O-Demethyl Apremilast

    4'-hydroxy APR

     An active metabolite of apremilast O-Demethyl Apremilast Chemical Structure
  73. GC40256 p-APMSF (hydrochloride)

    (p-Amidinophenyl)methanesulfonyl Fluoride, para-APMSF

     p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. p-APMSF (hydrochloride) Chemical Structure
  74. GC49024 Palmitic Acid MaxSpec® Standard

    C16:0, Cetylic Acid, NSC 5030

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  75. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    C16:0-d9, Cetylic Acid-d9

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  76. GC49702 Papain Inhibitor (trifluoroacetate salt)

    GGYR, Gly-Gly-Tyr-Arg

     A peptide inhibitor of papain Papain Inhibitor (trifluoroacetate salt) Chemical Structure
  77. GC40622 Penicillide

    Vermixocin A

     Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. Penicillide Chemical Structure
  78. GC40265 Pheleuin Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde. Pheleuin Chemical Structure
  79. GC46019 Pluviatolide

    (–)-Pluviatolide

     A lignan Pluviatolide Chemical Structure
  80. GC49108 Racecadotril-d5

    Acetorphan-d5

     An internal standard for the quantification of racecadotril Racecadotril-d5 Chemical Structure
  81. GC48101 SSAA09E1 A SARS-CoV entry inhibitor SSAA09E1 Chemical Structure
  82. GC18565 Suc-AAP-Abu-pNA

    Elastase Colorimetric Substrate IV

     Suc-AAP-Abu-pNA is a chromogenic peptide substrate for pancreatic elastase. Suc-AAP-Abu-pNA Chemical Structure
  83. GC52447 Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt)

    Suc-LLVY-AMC

     A fluorogenic substrate for the 20S proteasome and calpains Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) Chemical Structure
  84. GC44963 Suc-Leu-Tyr-AMC

    SucLYAMC

     The calpains are a family of calcium-dependent cysteine proteases, with calpain I (μ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC Chemical Structure
  85. GA23570 Suc-Tyr-Val-Ala-Asp-pNA

    Caspase-1 and Caspase-4 Chromogenic Substrate, Suc-Tyr-Val-Ala-Asp-p-nitroanilide

     Suc-YVAD-pNA, a chromogenic caspase-1 substrate. Suc-Tyr-Val-Ala-Asp-pNA Chemical Structure
  86. GC44967 Suc-YVAD-AMC (acetate)

    Suc-Tyr-Val-Ala-Asp-AMC, Suc-Tyr-Val-Ala-Asp-7-amino-4-methylcoumarin, Suc-YVAD-NH-Mec

     Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Suc-YVAD-AMC (acetate) Chemical Structure
  87. GC48764 Sydowinin B

    MS-347b

     A xanthone polyketide with immunosuppressant activity Sydowinin B Chemical Structure
  88. GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan Thiorphan-d5 Chemical Structure
  89. GC45066 Tosyl Phenylalanyl Chloromethyl Ketone

    Nα-Tosyl-L-Phenylalanine Chloromethyl Ketone, TPCK

     Tosyl Phenylalanyl Chloromethyl Ketone (L-1-Tosylamido-2-phenylethyl chloromethyl ketone; L-Tosyl Phenylalanyl Chloromethyl Ketone) is a potent serine protease inhibitor that reacts with the retinoblastoma protein (RB)-binding core of HPV-18 E7 protein and abolish its RB-binding capability. Tosyl Phenylalanyl Chloromethyl Ketone Chemical Structure
  90. GC49685 Trifluoroacetyl Tripeptide-2 (acetate)

    F3Ac-Val-Tyr-Val

     A peptide inhibitor of pancreatic and neutrophil elastases Trifluoroacetyl Tripeptide-2 (acetate) Chemical Structure
  91. GC45086 Trigalacturonic Acid

    Trigalacturonic acid is an oligosaccharide that inhibits proteinase activity in tomato plants (ED50 = 2.6 μg/plant).

     Trigalacturonic Acid Chemical Structure
  92. GC49835 Tumulosic Acid

    Polyporenic Acid B

     Tumulosic Acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic Acid Chemical Structure
  93. GC48471 Z-(L-Arg)-AMC (hydrochloride)

    Bz-Arg-AMC, N-benzoxy-L-Arg-7-amido-4-methylcoumarin, N-benzoyl-L-Arg-AMC, Z-Arg(HCl)AMC

     Z-(L-Arg)-AMC (hydrochloride) is a fluorogenic substrate for trypsin and papain. Z-(L-Arg)-AMC (hydrochloride) Chemical Structure
  94. GC45177 Z-AEVD-FMK

    Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone

    Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.

     Z-AEVD-FMK Chemical Structure
  95. GA23742 Z-D-Arg-Gly-Arg-pNA . 2 HCl

    Benzyl-D-Arg-Gly-Arg-pNA, Benzyl-D-Arg-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate, S-2765

     Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa. Z-D-Arg-Gly-Arg-pNA . 2 HCl Chemical Structure
  96. GC13859 Z-DEVD-AFC

    Caspase-3 Fluorogenic Substrate IV

     A caspase-3 fluorogenic substrate Z-DEVD-AFC Chemical Structure
  97. GC49145 Z-FR-AMC (trifluoroacetate salt)

    Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC

     A fluorogenic substrate for cathepsin L Z-FR-AMC (trifluoroacetate salt) Chemical Structure
  98. GC45181 Z-IETD-AFC

    Z-Ile-Glu-Thr-Asp-7-amino-4-Trifluormethylcoumarin

     Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B. Z-IETD-AFC Chemical Structure
  99. GC40151 Z-VAD-AMC (acetate)

    Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin

     Z-VAD-AMC is a fluorogenic substrate for caspase-1. Z-VAD-AMC (acetate) Chemical Structure

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