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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Targets for  Endocrinology and Hormones

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC12126 Flutamide Androgen receptor antagonists Flutamide Chemical Structure
  3. GC48831 Flutamide-d7 An internal standard for the quantification of flutamide Flutamide-d7 Chemical Structure
  4. GC45455 Fluticasone 17β-Carboxylic Acid   Fluticasone 17β-Carboxylic Acid Chemical Structure
  5. GC12815 Formestane Type I steroidal aromatase inhibitor Formestane Chemical Structure
  6. GC60857 Frakefamide TFA Frakefamide TFA is a potent analgesic that acts as a peripheral active μ-selective receptor agonist. Frakefamide TFA Chemical Structure
  7. GC18000 Fulvestrant (ICI 182,780)

    Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades ER, then inhibits ER-mediated transcriptional activity with an IC50 of 9.4 nM.

     Fulvestrant (ICI 182,780) Chemical Structure
  8. GC49878 Fulvestrant 9-sulfone An estrogen receptor antagonist and a derivative of fulvestrant Fulvestrant 9-sulfone Chemical Structure
  9. GC12766 G-1

    G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM.

     G-1 Chemical Structure
  10. GC16618 G-15

    A GPER receptor antagonist

     G-15 Chemical Structure
  11. GC14902 G-36

    GPER activator

     G-36 Chemical Structure
  12. GC43736 Ganirelix (acetate) Ganirelix is a gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3.6 nM; pA2 = 9.3). Ganirelix (acetate) Chemical Structure
  13. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM Chemical Structure
  14. GC10017 Gestodene Progestogen hormonal contraceptive Gestodene Chemical Structure
  15. GC48763 Gestodene-d6 An internal standard for the quantification of gestodene Gestodene-d6 Chemical Structure
  16. GC52506 Ghrelin (human) (trifluoroacetate salt) A growth hormone releasing peptide Ghrelin (human) (trifluoroacetate salt) Chemical Structure
  17. GC43754 Ghrelin (rat) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Ghrelin (rat) (trifluoroacetate salt) Chemical Structure
  18. GC45459 GHRP-6 (acetate)   GHRP-6 (acetate) Chemical Structure
  19. GC45462 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)   GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt) Chemical Structure
  20. GC43764 GLP-2 (human) (trifluoroacetate salt) Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion. GLP-2 (human) (trifluoroacetate salt) Chemical Structure
  21. GC30086 GLPG0492 A selective androgen receptor modulator GLPG0492 Chemical Structure
  22. GC30101 GLPG0492 R enantiomer GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator. GLPG0492 R enantiomer Chemical Structure
  23. GP10122 Glucagon (19-29), human Glucagon (19-29), human Chemical Structure
  24. GC52490 Glucagon (hydrochloride) A peptide hormone Glucagon (hydrochloride) Chemical Structure
  25. GC49342 Glucagon-d9 (trifluoroacetate salt) An internal standard for the quantification of glucagon Glucagon-d9 (trifluoroacetate salt) Chemical Structure
  26. GC40049 Glucocorticoid Resistance Inhibitor Glucocorticoid resistance inhibitor is an inhibitor of glucocorticoid resistance. Glucocorticoid Resistance Inhibitor Chemical Structure
  27. GC62992 Glutaurine Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine Chemical Structure
  28. GC30328 Gluten Exorphin C Gluten exorphin C is an opioid peptide derived from wheat gluten. Gluten Exorphin C Chemical Structure
  29. GC40911 Glycine-β-muricholic Acid Glycine-β-muricholic Acid, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders. Glycine-β-muricholic Acid Chemical Structure
  30. GC45466 Glyco-Obeticholic Acid   Glyco-Obeticholic Acid Chemical Structure
  31. GC62644 GnRH antagonist 2 GnRH antagonist 2 (formula I) is a GnRH receptor antagonist that can be used for endometriosis research. GnRH antagonist 2 Chemical Structure
  32. GP10043 GnRH Associated Peptide (GAP) (1-13), human

    Inhibitor of prolactin secretion

     GnRH Associated Peptide (GAP) (1-13), human Chemical Structure
  33. GC15843 GNTI dihydrochloride κ opioid receptor antagonist GNTI dihydrochloride Chemical Structure
  34. GC34001 Gonadorelin acetate A tropic hormone Gonadorelin acetate Chemical Structure
  35. GC36180 Goserelin acetate A synthetic GNRH agonist Goserelin acetate Chemical Structure
  36. GC14739 GR 89696 fumarate κ-opioid agonist GR 89696 fumarate Chemical Structure
  37. GP10024 Growth Hormone (1-43), human Human Growth Hormone (1-43) peptide Growth Hormone (1-43), human Chemical Structure
  38. GC43785 GRP (porcine) (trifluoroacetate salt) Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. GRP (porcine) (trifluoroacetate salt) Chemical Structure
  39. GC10558 GSK 4716 estrogen-related receptors ERRβ and ERRγ agonist GSK 4716 Chemical Structure
  40. GC68427 GSK1521498 free base GSK1521498 free base Chemical Structure
  41. GC31331 GSK2033

    An antagonist of LXRα and LXRβ

     GSK2033 Chemical Structure
  42. GC17679 GSK2881078 selective androgen receptor modulator (SARM) GSK2881078 Chemical Structure
  43. GC48610 GSK3987 A dual agonist of LXRα and LXRβ GSK3987 Chemical Structure
  44. GC45678 Guanoclor A guanidinium antihypertensive Guanoclor Chemical Structure
  45. GC49048 Guanylin (human) (trifluoroacetate salt) A peptide hormone activator of GC-C Guanylin (human) (trifluoroacetate salt) Chemical Structure
  46. GC17658 Guggulsterone Broad spectrum steroid receptor ligand Guggulsterone Chemical Structure
  47. GC16964 GW3965 An orally-active agonist of LXRα and LXRβ GW3965 Chemical Structure
  48. GC17696 GW3965 HCl GW3965 HCl is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively. GW3965 HCl Chemical Structure
  49. GC10975 GW4064

    GW4064, as a synthetic FXR agonist, was used for treatment of cholestatic liver diseases, metabolic syndrome and alcoholic liver disease.

     GW4064 Chemical Structure
  50. GA22290 H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH₂ CTAP, an analog of CTOP, is a selective µ-opioid receptor antagonist. H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH₂ Chemical Structure
  51. GC49385 Halometasone A synthetic corticosteroid Halometasone Chemical Structure
  52. GC14221 HE-3235 HE-3235, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. HE-3235 is active in rodent models of prostate and breast cancer. HE-3235 Chemical Structure
  53. GC43808 Hecogenin Acetate Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. Hecogenin Acetate Chemical Structure
  54. GC32489 Hemorphin-7 Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin-7 Chemical Structure
  55. GC15324 Hexestrol Estrogen receptor agonist Hexestrol Chemical Structure
  56. GC43866 Histrelin (acetate) Histrelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor (GNRHR; Ki = 0.2 nM in CHO cells expressing the human receptor). Histrelin (acetate) Chemical Structure
  57. GC62249 Honokiol DCA Honokiol DCA Chemical Structure
  58. GC43873 Hydrocortisone 21-hemisuccinate (sodium salt) Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. Hydrocortisone 21-hemisuccinate (sodium salt) Chemical Structure
  59. GC52043 Hydrocortisone Aceponate Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone Aceponate Chemical Structure
  60. GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone Hydrocortisone-d4 Chemical Structure
  61. GC15599 Hydroxyprogesterone caproate synthetic progestational agent Hydroxyprogesterone caproate Chemical Structure
  62. GC11639 ICI 154,129 Selective δ opioid antagonist ICI 154,129 Chemical Structure
  63. GC16193 ICI 174,864 Selective δ opioid antagonist ICI 174,864 Chemical Structure
  64. GC12534 ICI 199,441 hydrochloride ICI 199,441 hydrochloride is a potent and selective κ-opioid receptor agonist. ICI 199,441 hydrochloride Chemical Structure
  65. GC13097 ICI 204,448 hydrochloride κ opioid receptor agonist ICI 204,448 hydrochloride Chemical Structure
  66. GC50201 IHR 1 Potent Smo antagonist IHR 1 Chemical Structure
  67. GC13078 Imidapril HCl Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril HCl Chemical Structure
  68. GC32742 INT-767 INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively. INT-767 Chemical Structure
  69. GC49634 Isoflupredone Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone Chemical Structure
  70. GC49306 Isopimaric Acid A diterpenoid resin acid Isopimaric Acid Chemical Structure
  71. GC36344 Isosilybin B Isosilybin B, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation. Isosilybin B Chemical Structure
  72. GC15382 Isotretinoin A retinoid Isotretinoin Chemical Structure
  73. GC47474 Itraconazole-d5 An internal standard for the quantification of itraconazole Itraconazole-d5 Chemical Structure
  74. GC17939 JDTic JDTic Chemical Structure
  75. GC17624 JDTic 2HCl JDTic 2HCl Chemical Structure
  76. GC43929 JMV3002 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 Chemical Structure
  77. GC62106 JNJ-63576253 JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC). JNJ-63576253 Chemical Structure
  78. GC11826 JTC-801 KOR-3 (NOP) receptor antagonist JTC-801 Chemical Structure
  79. GC43934 Juvenile Hormone III

    Juvenile hormone III is an acyclic sesquiterpenoid that regulates diverse processes in insects, including adult transition of larvae and oogenesis in adult females.

     Juvenile Hormone III Chemical Structure
  80. GC31616 KAT681 (T0681) KAT681 (T0681) is a liver-selective thyromimetic. KAT681 (T0681) Chemical Structure
  81. GC48432 KB-130015 An antiarrhythmic agent KB-130015 Chemical Structure
  82. GC31151 Kelatorphan Kelatorphan is a full inhibitor of enkephalin degrading enzymes. Kelatorphan Chemical Structure
  83. GC40109 Ketoconazole-d3 Ketoconazole-d3 is intended for use as an internal standard for the quantification of ketoconazole by GC- or LC-MS. Ketoconazole-d3 Chemical Structure
  84. GC45490 Kisspeptin-54 (human) (trifluoroacetate salt)   Kisspeptin-54 (human) (trifluoroacetate salt) Chemical Structure
  85. GC11268 L-Thyroxine

    Iodine containing hormone

     L-Thyroxine Chemical Structure
  86. GC61010 L-Thyroxine sodium L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. L-Thyroxine sodium Chemical Structure
  87. GC36487 L-Thyroxine sodium salt pentahydrate L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. L-Thyroxine sodium salt pentahydrate Chemical Structure
  88. GC44088 L-Thyroxine-13C9,15N L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine-13C9,15N Chemical Structure
  89. GC52021 L-Thyroxine-N-methylamide A potential impurity found in commercial preparations of L-thyroxine L-Thyroxine-N-methylamide Chemical Structure
  90. GC48937 L-Tyrosine-13C9,15N An internal standard for the quantification of L-tyrosine L-Tyrosine-13C9,15N Chemical Structure
  91. GC65936 Larsucosterol (trimethylamine) Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1. Larsucosterol (trimethylamine) Chemical Structure
  92. GC44036 Lasofoxifene Lasofoxifene is a third-generation, non-steroidal selective estrogen receptor modulator (SERM). Lasofoxifene Chemical Structure
  93. GC11425 Lasofoxifene (tartrate) third-generation, non-steroidal selective estrogen receptor modulator (SERM) Lasofoxifene (tartrate) Chemical Structure
  94. GC12294 LE 135 RARβ antagonist LE 135 Chemical Structure
  95. GC33034 Lecirelin Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin Chemical Structure
  96. GC18496 Leelamine (hydrochloride) Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine (hydrochloride) Chemical Structure
  97. GP10031 Leptin (116-130) amide (mouse) Leptin (116-130) amide (mouse) Chemical Structure
  98. GC10726 Letrozole Non-steroidal aromatase inhibitor Letrozole Chemical Structure
  99. GC47554 Letrozole-d4 An internal standard for the quantification of letrozole Letrozole-d4 Chemical Structure
  100. GC10076 Leuprolide Acetate A synthetic GnRH receptor agonist Leuprolide Acetate Chemical Structure
  101. GC14704 Levonorgestrel Estrogen/progestogen receptor agonist Levonorgestrel Chemical Structure

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