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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Targets for  Endocrinology and Hormones

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC42797 Amylin (rat, mouse) (trifluoroacetate salt)

    IAPP (rat, mouse), Islet Amyloid Polypeptide (rat, mouse)

     Amylin is a 37-residue peptide hormone secreted by pancreatic β-cells that reduces food intake, modifies glycogen synthesis, slows gastric emptying, and increases satiety. Amylin (rat, mouse) (trifluoroacetate salt) Chemical Structure
  3. GC10256 Anastrozole

    Anastrol, ICID 1033, ZD 1033

    Aromatase inhibitor

     Anastrozole Chemical Structure
  4. GC46854 Anastrozole-d12

    Anastrol-d12

     An internal standard for the quantification of anastrozole Anastrozole-d12 Chemical Structure
  5. GC13685 Andarine

    Andarine, S-4, SARM S-4

     Andarine (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. Andarine (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity. Andarine Chemical Structure
  6. GC67698 Androgen receptor-IN-2 Androgen receptor-IN-2 Chemical Structure
  7. GC73577 Androgen receptor-IN-6 Androgen receptor-IN-6 (compound 16) is an orally available androgen receptor (Androgen Receptor) potent inhibitor (IC50=0.12 μM in vitro), targeting the disordered N-terminal domain (NTD). Androgen receptor-IN-6 Chemical Structure
  8. GC31254 Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate) Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate) Chemical Structure
  9. GC34887 Androstanolone acetate Androstanolone acetate Chemical Structure
  10. GC30842 Androsterone (5α-Androstan-3α-ol-17-one)

    Androkinin, NSC 9898

    An androgenic steroid

     Androsterone (5α-Androstan-3α-ol-17-one) Chemical Structure
  11. GP10074 Angiotensin 1/2 (1-5)

    H2N-Asp-Arg-Val-Tyr-Ile-OH

    Angiotensin 1/2 (1-5) Chemical Structure
  12. GP10067 Angiotensin 1/2 (1-6)

    H2N-Asp-Arg-Val-Tyr-Ile-His-OH

    Angiotensin 1/2 (1-6) Chemical Structure
  13. GP10144 Angiotensin 1/2 (1-7) amide

    H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide

    Angiotensin 1/2 (1-7) amide Chemical Structure
  14. GP10012 Angiotensin 1/2 (1-8) amide

    H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide

    Vasoconstrictor

     Angiotensin 1/2 (1-8) amide Chemical Structure
  15. GP10025 Angiotensin 1/2 (1-9) Angiotensin 1/2 (1-9) Chemical Structure
  16. GP10045 Angiotensin 1/2 (2-7)

    H2N-Arg-Val-Tyr-Ile-His-Pro-OH

    Vasoconstrictor

     Angiotensin 1/2 (2-7) Chemical Structure
  17. GP10079 Angiotensin 1/2 (5-7)

    H2N-Ile-His-Pro-OH

    Angiotensin 1/2 (5-7) Chemical Structure
  18. GP10120 Angiotensin 1/2 + A (2 - 8)

    H2N-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

    Vasoconstrictor Angiotensin 1/2 + A (2 - 8) Chemical Structure
  19. GC52415 Angiotensin A (trifluoroacetate salt)

    Ala-Arg-Val-Tyr-Ile-His-Pro-Phe, DesAsp1-Ala1-Ang II

     An AT1 and AT2 receptor agonist and active metabolite of angiotensin II Angiotensin A (trifluoroacetate salt) Chemical Structure
  20. GP10087 Angiotensin I (human, mouse, rat) Angiotensin I (human, mouse, rat) Chemical Structure
  21. GC46856 Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)

    Angiotensin (5-8)

    An endogenous angiotensin II fragment

     Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt) Chemical Structure
  22. GC42815 Ansatrienin A

    Mycotrienin I

     Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. Ansatrienin A Chemical Structure
  23. GC46859 Antide (acetate) A GnRHR antagonist Antide (acetate) Chemical Structure
  24. GC46860 AP-238 (hydrochloride)

    2,6-dimethyl Propionyl AP-237

     A neuropeptide with diverse biological activities AP-238 (hydrochloride) Chemical Structure
  25. GC60589 Apalutamide D4

    ARN-509-d4

     Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. Apalutamide D4 Chemical Structure
  26. GC12219 AR-M 1000390 hydrochloride Delta-opioid receptor agonist,low-internalizing AR-M 1000390 hydrochloride Chemical Structure
  27. GC64540 Ar-V7-IN-1 Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications, in particular cancers such as prostate cancer (extracted from patent WO2018114781A1, compound 43). Ar-V7-IN-1 Chemical Structure
  28. GC19035 AR7 A retinoic acid receptor α (RARα) antagonist AR7 Chemical Structure
  29. GC73613 ARD-1676 ARD-1676 is an orally available androgen receptor (AR) PROTAC degrader, consisting of AR ligand and cereblon ligand. ARD-1676 Chemical Structure
  30. GC73277 ARD-2051 ARD-2051 is a potent and orally active androgen receptor (AR) proteolysis-targeting chimera degrader. ARD-2051 Chemical Structure
  31. GC72850 ARD-69 ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 Chemical Structure
  32. GC42852 Arginine Vasotocin (trifluoroacetate salt)

    Arg8-Vasotocin, AVT

     Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor (EC50 = 13 nM for eliciting membrane currents in X. Arginine Vasotocin (trifluoroacetate salt) Chemical Structure
  33. GC16840 ARN-509

    ARN 509; ARN509

     ARN-509 (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. ARN-509 Chemical Structure
  34. GC62118 ARV-110

    ARV-110

     ARV-110 (ARV-110) is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer. ARV-110 Chemical Structure
  35. GC10547 ASC-J9 A selective enhancer of AR degradation ASC-J9 Chemical Structure
  36. GC31762 Asimadoline (EMD-61753)

    EMD 61753

     Asimadoline (EMD-61753) (EMD-61753) is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline (EMD-61753) Chemical Structure
  37. GC61397 Asimadoline hydrochloride Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride Chemical Structure
  38. GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid ATRA-BA Hybrid Chemical Structure
  39. GC66207 Atraric acid

    Methyl atrarate

     Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases. Atraric acid Chemical Structure
  40. GC42870 Atrazine Mercapturate

    ATR Mercapturate

     Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine, an herbicide that is effective in controlling a broad range of weeds. Atrazine Mercapturate Chemical Structure
  41. GC49321 AZ-GHS-22 An inverse agonist of GHS-R1a AZ-GHS-22 Chemical Structure
  42. GC32801 AZ876 An LXR agonist AZ876 Chemical Structure
  43. GC12434 AZD1981 CRTh2 antagonist,potent and selective AZD1981 Chemical Structure
  44. GC10372 AZD3514 Androgen receptor downregulator AZD3514 Chemical Structure
  45. GC14405 AZD9496 estrogen receptor inhibitor, orally active AZD9496 Chemical Structure
  46. GC11390 BAM 22P

    Bovine adrenal medulla-22P

     Potent endogenous agonist peptide for the newly identified sensory neuron specific receptor (SNSR); BAM 22P Chemical Structure
  47. GC72096 Bamadutide Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor agonist. Bamadutide Chemical Structure
  48. GC15926 BAN ORL 24 A nociceptin receptor antagonist BAN ORL 24 Chemical Structure
  49. GC30565 BAR502 A dual agonist of GP-BAR1 and FXR BAR502 Chemical Structure
  50. GC17588 Bavachin

    Corylifolin

     estrogen receptors ERα and ERβ activator Bavachin Chemical Structure
  51. GC14883 Bazedoxifene Bazedoxifene Chemical Structure
  52. GC10852 Bazedoxifene acetate

    TSE 424

     A selective estrogen receptor modulator Bazedoxifene acetate Chemical Structure
  53. GC10245 Bazedoxifene HCl Bazedoxifene HCl (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene HCl can be used for the research of osteoporosis. Bazedoxifene HCl acts as an inhibitor of IL-6/GP130 protein-protein interactions. Bazedoxifene HCl can be used for the research of pancreatic cancer. Bazedoxifene HCl Chemical Structure
  54. GC49757 Bazedoxifene N-oxide An oxidative degradation product of bazedoxifene Bazedoxifene N-oxide Chemical Structure
  55. GC46907 Bazedoxifene-d4 An internal standard for the quantification of bazedoxifene Bazedoxifene-d4 Chemical Structure
  56. GC46909 BE-26263 A fungal metabolite BE-26263 Chemical Structure
  57. GP10051 Beta-Lipotropin (1-10), porcine

    H2N-Glu-Leu-Ala-Gly-Ala-Pro-Pro-Glu-Pro-Ala-OH

    Morphine-like substance

     Beta-Lipotropin (1-10), porcine Chemical Structure
  58. GC20142 Beta-Sitosterol

    β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%))

     Beta-Sitosterol is a plant sterol with multiple biological activities, including anti-inflammatory, anti-tumor, antipyretic and immunomodulatory activities. Beta-Sitosterol Chemical Structure
  59. GC52329 Betamethasone-d5

    β-Methasone-d5, SCH 4831-d5

     An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure
  60. GC30639 Bevenopran (CB-5945)

    CB-5945; ADL-5945

     Bevenopran (CB-5945) is a peripheral μ-opioid receptor antagonist. Bevenopran (CB-5945) Chemical Structure
  61. GC10037 Bexarotene

    LG 100069, LGD 1069, Ro 264455, SR 11247

     Retinoid Receptor agonist Bexarotene Chemical Structure
  62. GC46923 Bexarotene-d4

    LGD1069 D4

     A neuropeptide with diverse biological activities Bexarotene-d4 Chemical Structure
  63. GC12271 Bicalutamide

    ICI 176334, ZD 176334

     Androgen receptor antagonist Bicalutamide Chemical Structure
  64. GC46925 Bicalutamide-d4 An internal standard for the quantification of bicalutamide Bicalutamide-d4 Chemical Structure
  65. GC31577 Bifluranol (BX341)

    BX341

     Bifluranol (BX341) (BX341) is an anti-androgen. Bifluranol (BX341) Chemical Structure
  66. GC60076 Bigelovin Bigelovin, a sesquiterpene lactone isolated from Inula helianthus-aquatica, is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation. Bigelovin Chemical Structure
  67. GC42943 Bischloroanthrabenzoxocinone

    BABX, (―)-Bischloroanthrabenzoxocinone

     Bacterial type II fatty acid synthesis (FAS-II) is mediated by a series of enzymes, each of which may be targeted by potential antibiotics. Bischloroanthrabenzoxocinone Chemical Structure
  68. GC11504 BMS 195614

    BMS 614

     BMS 195614 (BMS 614) is a neutral RARα-selective antagonist with a Ki of 2.5 nM. BMS 195614 Chemical Structure
  69. GC49654 BMS 270394 A RARγ agonist BMS 270394 Chemical Structure
  70. GC10656 BMS 453

    BMS 189453

     RAR agonist BMS 453 Chemical Structure
  71. GC42954 BMS 470539 (hydrochloride)

    BMS 470539 is an agonist of melanocortin receptor 1 (MC1R) with EC50 values of 16.8 and 11.6 nM for human and murine MC1R, respectively, in a cAMP accumulation assay.

     BMS 470539 (hydrochloride) Chemical Structure
  72. GC15648 BMS 493

    BMS 204493

     Pan-RAR inverse agonist BMS 493 Chemical Structure
  73. GC14185 BMS 753 RARα-selective agonist BMS 753 Chemical Structure
  74. GC17382 BMS 961

    BMS 961

     Selective RARγ agonist BMS 961 Chemical Structure
  75. GC35534 BMS-564929 BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM. BMS-564929 Chemical Structure
  76. GC31372 BMS-779788 (EXEL04286652)

    EXEL04286652; XL-652; BMS-788

     BMS-779788 (EXEL04286652) is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ. BMS-779788 (EXEL04286652) Chemical Structure
  77. GC68785 BMS-986121

    BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor, derived from patent WO2014107344. BMS-986121 is built on a chemical scaffold and represents a new chemical type of μ receptor PAMs.

     BMS-986121 Chemical Structure
  78. GC68781 BMS641

    BMS-209641

    BMS641 (BMS-209641) is a selective RARβ agonist. BMS641 has 100 times higher affinity for RARβ (Kd, 2.5 nM) than for RARα (Kd, 225 nM) or RARγ (Kd, 223 nM).

     BMS641 Chemical Structure
  79. GA20967 Boc-D-His-OH

    N-(tert-Butoxycarbonyl)-D-histidine, N-(t-Butoxycarbonyl)-D-histidine, Nα-tert-Butoxycarbonyl-D-histidine

     An amino acid building block Boc-D-His-OH Chemical Structure
  80. GA20972 Boc-D-Leu-OSu An amino acid-containing building block Boc-D-Leu-OSu Chemical Structure
  81. GC41187 Boldenone Cypionate Boldenone is an anabolic androgenic steroid and synthetic derivative of testosterone that was originally developed for veterinary use. Boldenone Cypionate Chemical Structure
  82. GC35541 Boldenone Undecylenate

    Boldenone 10-Undecenoate

     Boldenone Undecylenate Chemical Structure
  83. GC46941 Bombesin (trifluoroacetate salt)

    Glp-Gln-Arg-LeuGly-Asn-GlnTrp-Ala-ValGly-His-LeuMet-NH2

     A neuropeptide with diverse biological activities Bombesin (trifluoroacetate salt) Chemical Structure
  84. GC38741 BPR1M97 BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. BPR1M97 Chemical Structure
  85. GC15313 BRL 52537 hydrochloride κ/μ opioid receptor agonist,potent and selective BRL 52537 hydrochloride Chemical Structure
  86. GC46954 Bromocriptine-13C-d3

    CB-154-13C-d3

     A neuropeptide with diverse biological activities Bromocriptine-13C-d3 Chemical Structure
  87. GC46956 Budesonide-d8 An internal standard for the quantification of budesonide Budesonide-d8 Chemical Structure
  88. GC34099 Buserelin Acetate Buserelin Acetate Chemical Structure
  89. GC42991 Buserelin-NHNH2 (trifluoroacetate salt) Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. Buserelin-NHNH2 (trifluoroacetate salt) Chemical Structure
  90. GC46104 Butyric Acid-d7 An internal standard for the quantification of sodium butyrate Butyric Acid-d7 Chemical Structure
  91. GC16521 BW 373U86

    SNC86

     Non-peptide delta agonist,potent and selective BW 373U86 Chemical Structure
  92. GC73237 BWA-522 BWA-522 is an orally available small molecule protein-targeting chimera (PROTACs) with significant degradation effect on AR-FL and AR-V7. BWA-522 Chemical Structure
  93. GC47016 Cabergoline-d6

    FCE-21336-d6

     A neuropeptide with diverse biological activities Cabergoline-d6 Chemical Structure
  94. GC43126 Calcitonin (human) (trifluoroacetate salt)

    Ba 47175, Calcitonin (1-32) (human), hCT, Thyrocalcitonin (human)

     Calcitonin is a peptide hormone that lowers blood calcium levels and inhibits bone resorption. Calcitonin (human) (trifluoroacetate salt) Chemical Structure
  95. GC43127 Calcitonin (salmon) (trifluoroacetate salt)

    Calcitonin (1-32) (salmon), Salcatonin, sCT, Thyrocalcitonin (salmon)

     Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. Calcitonin (salmon) (trifluoroacetate salt) Chemical Structure
  96. GC16978 Candesartan

    Candesartan M1, CV-11974

     Angiotensin II receptor 1 (AT1) antagonist Candesartan Chemical Structure
  97. GC16223 Captopril

    SA 333, SQ 14,225

     An ACE inhibitor Captopril Chemical Structure
  98. GC43140 Captopril Disulfide

    SQ 14,551

     Captopril disulfide is a metabolite and symmetrical disulfide form of the angiotensin converting enzyme (ACE) inhibitor captopril. Captopril Disulfide Chemical Structure
  99. GC48348 Carbetocin (acetate) A peptide oxytocin receptor agonist Carbetocin (acetate) Chemical Structure
  100. GC48426 CAY10771 A dual agonist of FXR and PPARδ CAY10771 Chemical Structure
  101. GC67907 CCG258747 CCG258747 Chemical Structure

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