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Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

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  1. Cat.No. Product Name Information
  2. GC65260 EDP-305 EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305  Chemical Structure
  3. GC19135 Elagolix Elagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). Elagolix  Chemical Structure
  4. GC19136 Elagolix sodium Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. Elagolix sodium  Chemical Structure
  5. GC67956 Endomorphin 1 acetate Endomorphin 1 acetate  Chemical Structure
  6. GC35986 Endomorphin 2 TFA Endomorphin 2 TFA, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 2 TFA  Chemical Structure
  7. GP10065 Endomorphin-1 Endomorphin-1  Chemical Structure
  8. GC10059 Endomorphin-2

    μ-opioid receptors agonist

    Endomorphin-2  Chemical Structure
  9. GC12140 Endoxifen Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen  Chemical Structure
  10. GC49648 Enobosarm-d4

    (S)-Enobosarm-d4

    An internal standard for the quantification of enobosarm Enobosarm-d4  Chemical Structure
  11. GC64854 Enzalutamide-d3 Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide-d3  Chemical Structure
  12. GC69072 Enzalutamide-d6

    MDV3100-d6

    Enzalutamide-d6 is a deuterium-labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cancer cells.

    Enzalutamide-d6  Chemical Structure
  13. GC16631 EPI-001 AR antagonist EPI-001  Chemical Structure
  14. GC73291 EPI-7170 EPI-7170, a ralaniten analogue, is a potent androgen receptor N-terminal structural domain antagonist that blocks the transcriptional activity of full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170  Chemical Structure
  15. GC13072 Epiandrosterone

    5α-Androstan-3β-ol-17-one, Isoandrosterone, trans-Androsterone, NSC 93996

    steroid hormone with weak androgenic activity Epiandrosterone  Chemical Structure
  16. GC32953 Epristeride (ONO-9302) Epristeride (ONO-9302) (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride (ONO-9302) has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride (ONO-9302) can be used for the research of prostatic hyperplasia and acne. Epristeride (ONO-9302)  Chemical Structure
  17. GC33764 Eprotirome (KB2115)

    Eprotirome

    Eprotirome (KB2115) (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. Eprotirome (KB2115)  Chemical Structure
  18. GC18333 Equilenin

    (+)-Equilenin, d-Equilenin, NSC 9901

    Equilenin is an equine estrogen found in the urine of pregnant mares. Equilenin  Chemical Structure
  19. GC16292 Equol non-steroidal estrogen Equol  Chemical Structure
  20. GC12577 ER 50891 RARα receptor antagonist ER 50891  Chemical Structure
  21. GC72808 ER 50891 quarterhydrate ER 50891 quarterdrate is a potent antagonist of retinoic acid receptor α(RARα). ER 50891 quarterhydrate  Chemical Structure
  22. GC10389 ERB 041 ERB 041 (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. ERB 041 displays >200-fold selectivity for ERβ over ERα. ERB 041 is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. ERB 041 induces ovarian cancer apoptosis. ERB 041  Chemical Structure
  23. GC11822 Erteberel (LY500307)

    LY500307

    Erteberel (LY500307) (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Erteberel (LY500307)  Chemical Structure
  24. GC47309 Estetrol (hydrate)

    E4, 15α-Hydroxyestriol

    A naturally occurring estrogen Estetrol (hydrate)  Chemical Structure
  25. GC48979 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

    E217G, βEstradiol 17(βDGlucuronide), 17βEstradiol 17(βDGlucuronide), 17βOestradiol 17(βDGlucuronide)

    A substrate of multidrug resistance protein 2 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)  Chemical Structure
  26. GC43629 Estradiol 3-sulfate 17β-Glucuronide (potassium salt) Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol, and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Estradiol 3-sulfate 17β-Glucuronide (potassium salt)  Chemical Structure
  27. GC10139 Estradiol Cypionate

    Estradiol 17β-Cyclopentanepropionate, Estradiol 17-Cypionate, NSC 3354

    Estrogen receptor inhibitor Estradiol Cypionate  Chemical Structure
  28. GC11796 Estradiol valerate

    Estradiol 17β-valerate, NSC 17590

    Estradiol valerate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs. Estradiol valerate  Chemical Structure
  29. GC12182 Estriol

    E3, 16α-hydroxy-17β-Estradiol, 1,3,5(10)-Estratriene-3,16α,17β-triol

    Estrogen receptor antagonist Estriol  Chemical Structure
  30. GC43630 Estriol 3-β-D-Glucuronide (sodium salt)

    Estriol sodium 3-glucuronate

    Estriol 3-β-D-glucuronide is a metabolite of estriol. Estriol 3-β-D-Glucuronide (sodium salt)  Chemical Structure
  31. GC45450 Estriol-d2

    E3-d2, 16αhydroxy17βEstradiol-d2, 1,3,5(10)Estratriene3,16α,17βtriol-d2

    Estriol-d2 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Estriol-d2  Chemical Structure
  32. GC14385 Estrone

    E1

    Estrone is one of the three major endogenous estrogens, the others being estradiol and estriol. Estrone  Chemical Structure
  33. GC45451 Estrone 3-methyl ether

    (+)-Estrone methyl ether, 3-O-methyl Estrone, NSC 88911

      Estrone 3-methyl ether  Chemical Structure
  34. GC49254 Estrone-3-Glucuronide (sodium salt hydrate)

    E1G, Estrone Glucuronide, Estrone β-D-Glucuronide

    A metabolite of 17β-estradiol Estrone-3-Glucuronide (sodium salt hydrate)  Chemical Structure
  35. GC45452 Estrone-d2

    E1-d2

      Estrone-d2  Chemical Structure
  36. GC16852 Estropipate

    Piperazine Estrone Sulfate

    Estrogen receptor agonist Estropipate  Chemical Structure
  37. GC12148 Ethinyl Estradiol

    Ethynyl βEstradiol, Ethynyl 17βEstradiol, Ethynyl 17βOestradiol, Ethynyl E2

    Ethinyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethinyl Estradiol  Chemical Structure
  38. GC11436 Ethisterone Progestogen hormone Ethisterone  Chemical Structure
  39. GC12000 Ethynodiol diacetate

    SC-11800

    Progestogen receptor agonist Ethynodiol diacetate  Chemical Structure
  40. GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)

    17α-Ethynylestradiol 3-Glucuronide

    A metabolite of ethynyl estradiol Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)  Chemical Structure
  41. GC13303 Etonogestrel

    ORG 3236, 3-keto Desogestrel, 3-oxo Desogestrel

    steroidal progestin Etonogestrel  Chemical Structure
  42. GC32451 Examorelin (Hexarelin)

    Examorelin, H-2-Me-WAWFK, His-2-Me-Trp-Ala-Trp-Phe-Lys-NH2, His-(D)-Mrp-Ala-Trp-(D)-Phe-Lys-NH2

    A peptide agonist of GHS-R Examorelin (Hexarelin)  Chemical Structure
  43. GC11813 Exemestane

    Aromasin, FCE 24304

    Steroidal aromatase inhibitor,selective and irreversible Exemestane  Chemical Structure
  44. GC63755 Exemestane-D2

    FCE 24304-D2; EXE-D2

    Exemestane-D2  Chemical Structure
  45. GC19151 Fadrozole Fadrozole (CGS 16949A) is a selective, non-steroidal aromatase inhibitor with an IC50 value of 4.5μM. Fadrozole  Chemical Structure
  46. GC18301 Fadrozole (hydrochloride)

    CGS 16949A

    Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1.4 nM for human placental and rat ovarian microsomal aromatase, respectively). Fadrozole (hydrochloride)  Chemical Structure
  47. GC25410 Fasiglifam (TAK-875) Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid. Fasiglifam (TAK-875)  Chemical Structure
  48. GC49563 Fenhexamid

    KBR 2738

    Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid  Chemical Structure
  49. GC17143 Fenretinide

    4-HPR, 4-Hydroxy(phenyl)retinamide, MK-4016, Retinoic Acid p-hydroxyphenylamide, Ro 22-4667

    A synthetic retinoic acid derivative Fenretinide  Chemical Structure
  50. GC50190 Fenretinide - d4

    4-HPR-d4, 4-Hydroxy(phenyl)retinamide-d4, Retinoic Acid p-hydroxyphenylamide-d4

    Fenretinide - d4 is the deuterium labeled Fenretinide. Fenretinide - d4  Chemical Structure
  51. GC14131 FERb 033 ERβ receptor agonist FERb 033  Chemical Structure
  52. GC18641 Ferutinin Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM). Ferutinin  Chemical Structure
  53. GC10755 Fexaramine farnesoid X receptor agonist Fexaramine  Chemical Structure
  54. GC16248 Finasteride

    MK-906

    Inhibitor of Type II 5α-reductase Finasteride  Chemical Structure
  55. GC17572 Finasteride acetate 5α-reductase inhibitor Finasteride acetate  Chemical Structure
  56. GC60842 Finerenone

    BAY 94-8862

    Finerenone (BAY 94-8862) is a third-generation selective, orally active, nonsteroidal mineralocorticoid receptor (MR) antagonist with an IC50 of 18 nM. Finerenone  Chemical Structure
  57. GC15874 FIT

    δ-opioid agonist, irreversible

    FIT  Chemical Structure
  58. GC38682 Flavanone Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). Flavanone  Chemical Structure
  59. GC47361 Fludioxonil

    CGA 173506

    A fungicide Fludioxonil  Chemical Structure
  60. GC49631 Fluocortolone

    SH 742

    A glucocorticoid Fluocortolone  Chemical Structure
  61. GC11694 Fluorobexarotene

    RXR agonist

    Fluorobexarotene  Chemical Structure
  62. GC10618 Fluoxymesterone

    NSC 10704, NSC 12165

    androgen receptor agonist Fluoxymesterone  Chemical Structure
  63. GC10064 Flurizan

    E7869, Flurizan, Tarenflurbil

    A COX-inactive enantiomer of flurbiprofen Flurizan  Chemical Structure
  64. GC12126 Flutamide

    Niftolide, NSC 147834, NSC 251876, SCH 13521

    Androgen receptor antagonists Flutamide  Chemical Structure
  65. GC48831 Flutamide-d7

    SCH 13521-d7

    An internal standard for the quantification of flutamide Flutamide-d7  Chemical Structure
  66. GC45455 Fluticasone 17β-Carboxylic Acid   Fluticasone 17β-Carboxylic Acid  Chemical Structure
  67. GC12815 Formestane

    CGP 32349, Formestane, 4-HAD, 4-Hydroxy-androst-4-ene-3,17-dione, Lentaron, NSC 282175

    Type I steroidal aromatase inhibitor Formestane  Chemical Structure
  68. GC60857 Frakefamide TFA Frakefamide TFA is a potent analgesic that acts as a peripheral active μ-selective receptor agonist. Frakefamide TFA  Chemical Structure
  69. GC72225 Fsh receptor-binding inhibitor fragment(bi-10) FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. Fsh receptor-binding inhibitor fragment(bi-10)  Chemical Structure
  70. GC18000 Fulvestrant (ICI 182,780)

    ICI 182780

    Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades estrogen receptor, then inhibits estrogen receptor(ER)-mediated transcriptional activity with an IC50 of 9.4 nM . Fulvestrant (ICI 182,780)  Chemical Structure
  71. GC49878 Fulvestrant 9-sulfone An estrogen receptor antagonist and a derivative of fulvestrant Fulvestrant 9-sulfone  Chemical Structure
  72. GC40241 Fulvestrant-d3

    ICI 182780-d3; ZD 9238-d3; ZM 182780-d3

    Fulvestrant-d3 is intended for use as an internal standard for the quantification of fulvestrant by GC- or LC-MS. Fulvestrant-d3  Chemical Structure
  73. GC90891 Furosine (hydrochloride)

    An L-lysine derivative

    Furosine (hydrochloride)  Chemical Structure
  74. GC71185 FXR agonist 3 FXR agonist 3 is an anti-NASH agent, acting by activating FXR. FXR agonist 3  Chemical Structure
  75. GC69138 FXR agonist 5

    FXR agonist 5 (compound 1) is a type of FXR activator. FXR agonist 5 can be used to study diseases or disorders caused by metabolic inflammation.

    FXR agonist 5  Chemical Structure
  76. GC71156 FXR antagonist 1 FXR antagonist 1 (compound F6) is an orally active and selective intestinal FXR antagonist (IC50=2.1 μM). FXR antagonist 1  Chemical Structure
  77. GC12766 G-1 G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM. G-1  Chemical Structure
  78. GC16618 G-15

    A GPER receptor antagonist

    G-15  Chemical Structure
  79. GC14902 G-36

    GPER activator

    G-36  Chemical Structure
  80. GC74031 GA32 GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32  Chemical Structure
  81. GC43736 Ganirelix (acetate) Ganirelix is a gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3.6 nM; pA2 = 9.3). Ganirelix (acetate)  Chemical Structure
  82. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM  Chemical Structure
  83. GC10017 Gestodene Progestogen hormonal contraceptive Gestodene  Chemical Structure
  84. GC48763 Gestodene-d6

    SHB 331-d6; WL 70-d6

    An internal standard for the quantification of gestodene Gestodene-d6  Chemical Structure
  85. GC52506 Ghrelin (human) (trifluoroacetate salt)

    Lenomorelin

    A growth hormone releasing peptide Ghrelin (human) (trifluoroacetate salt)  Chemical Structure
  86. GC43752 Ghrelin (rat) (acetyl) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Ghrelin (rat) (acetyl) (trifluoroacetate salt)  Chemical Structure
  87. GC43753 Ghrelin (rat) (palmitoyl) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Ghrelin (rat) (palmitoyl) (trifluoroacetate salt)  Chemical Structure
  88. GC43754 Ghrelin (rat) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Ghrelin (rat) (trifluoroacetate salt)  Chemical Structure
  89. GC45803 GHRP-2 (trifluoroacetate salt)

    D-Ala-3-(2-naphthalenyl)-D-Ala-L-Ala-L-Trp-D-Phe-L-lysinamide, Growth Hormone-Releasing Peptide 2, KP-102, Pralmorelin

    A neuropeptide with diverse biological activities GHRP-2 (trifluoroacetate salt)  Chemical Structure
  90. GC45459 GHRP-6 (acetate)

    Growth Hormone Releasing Peptide 6, Hexapeptide-2, HWAWFK-NH2, SKF 110679, U 75799E

      GHRP-6 (acetate)  Chemical Structure
  91. GC45462 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

    Glucagon-like Peptide 1 (1-36) amide (human, rat)

      GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)  Chemical Structure
  92. GC43763 GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)

    Glucagon-like Peptide-1 (7-37) (human, bovine, guinea pig, mouse, rat)

    Glucagon-like peptide-1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) that is produced via cleavage of preproglucagon in the pancreas and intestine. GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)  Chemical Structure
  93. GC45463 GLP-2 (1-34) (human) (trifluoroacetate salt)

    Glucagon-like Peptide 2 (1-34)

      GLP-2 (1-34) (human) (trifluoroacetate salt)  Chemical Structure
  94. GC43764 GLP-2 (human) (trifluoroacetate salt)

    Glucagon-like Peptide-2

    Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion. GLP-2 (human) (trifluoroacetate salt)  Chemical Structure
  95. GC45464 GLP-2 (rat) (trifluoroacetate salt)

    Glucagon-like Peptide 2

      GLP-2 (rat) (trifluoroacetate salt)  Chemical Structure
  96. GC30086 GLPG0492 A selective androgen receptor modulator GLPG0492  Chemical Structure
  97. GC30101 GLPG0492 R enantiomer GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator. GLPG0492 R enantiomer  Chemical Structure
  98. GP10122 Glucagon (19-29), human

    H2N-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

    Glucagon (19-29), human  Chemical Structure
  99. GC52490 Glucagon (hydrochloride) A peptide hormone Glucagon (hydrochloride)  Chemical Structure
  100. GC49342 Glucagon-d9 (trifluoroacetate salt) An internal standard for the quantification of glucagon Glucagon-d9 (trifluoroacetate salt)  Chemical Structure
  101. GC40049 Glucocorticoid Resistance Inhibitor Glucocorticoid resistance inhibitor is an inhibitor of glucocorticoid resistance. Glucocorticoid Resistance Inhibitor  Chemical Structure

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