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Androgen Receptor

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Products for  Androgen Receptor

  1. Cat.No. Product Name Information
  2. GC45239 δ4-Abiraterone δ4-Abiraterone is a major metabolite of abiraterone. δ4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. δ4-Abiraterone  Chemical Structure
  3. GC61491 (R)-Bicalutamide (R)-Bicalutamide is the (R)-enantiomer of Bicalutamide. (R)-Bicalutamide is an androgen receptor (AR) antagonist, with antineoplastic activity. (R)-Bicalutamide is widely used for the research of prostate cancer. (R)-Bicalutamide  Chemical Structure
  4. GC30710 (R)-UT-155 (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer. (R)-UT-155  Chemical Structure
  5. GC63292 (rac)-PF-998425 (Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425  Chemical Structure
  6. GC49520 (S)-Equol

    An estrogen receptor β agonist

    (S)-Equol  Chemical Structure
  7. GC46456 16α-Hydroxyetiocholanolone A metabolite of 16α-DHEA and androstenedione 16α-Hydroxyetiocholanolone  Chemical Structure
  8. GC17557 17 alpha-propionate A peripherally selective androgen receptor antagonist 17 alpha-propionate  Chemical Structure
  9. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane. 17β-hydroxy Exemestane  Chemical Structure
  10. GC35069 2,2,5,7,8-Pentamethyl-6-Chromanol 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. 2,2,5,7,8-Pentamethyl-6-Chromanol  Chemical Structure
  11. GC17160 2-hydroxy Flutamide 2-hydroxy Flutamide (HF), an active metabolite of Flutamide, is a potent androgen receptor antagonist (IC50=700 nM). 2-hydroxy Flutamide can be used for the research of prostate cancer. 2-hydroxy Flutamide  Chemical Structure
  12. GC12791 3,3'-Diindolylmethane A phytochemical with antiradiation and chemopreventative effects 3,3'-Diindolylmethane  Chemical Structure
  13. GC49542 5α-Androstan-3β-ol A steroidal androgen 5α-Androstan-3β-ol  Chemical Structure
  14. GC48808 5β-Androstane-3α,17β-diol A metabolite of testosterone 5β-Androstane-3α,17β-diol  Chemical Structure
  15. GC49827 5-Androstenetriol An active metabolite of DHEA 5-Androstenetriol  Chemical Structure
  16. GC15774 5α-dihydro-11-keto Testosterone 5α-dihydro-11-keto Testosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 5α-dihydro-11-keto Testosterone  Chemical Structure
  17. GC49391 7α-Thiospironolactone An active metabolite of spironolactone 7α-Thiospironolactone  Chemical Structure
  18. GC63764 7-α-Methylthio Spironolactone-D3 7-α-Methylthio Spironolactone-D3  Chemical Structure
  19. GC48880 7-Methoxyflavone A flavone with diverse biological activities 7-Methoxyflavone  Chemical Structure
  20. GC46777 AC-262536 A selective androgen receptor modulator AC-262536  Chemical Structure
  21. GC31738 ACP-105 ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. ACP-105  Chemical Structure
  22. GC67703 Adrenocorticotropic hormone TFA Adrenocorticotropic hormone TFA  Chemical Structure
  23. GC31742 Ailanthone (δ13-Dehydrochaparrinone) Ailanthone (δ13-Dehydrochaparrinone) (δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) (IC50=69nM) and constitutively active truncated AR splice variants (AR1-651 IC50=309nM). Ailanthone (δ13-Dehydrochaparrinone)  Chemical Structure
  24. GC13685 Andarine Andarine (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. Andarine (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity. Andarine  Chemical Structure
  25. GC67698 Androgen receptor-IN-2 Androgen receptor-IN-2  Chemical Structure
  26. GC31254 Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate) Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- (Androst-4-ene-3β,17β-diol, dipropionate)  Chemical Structure
  27. GC34887 Androstanolone acetate Androstanolone acetate  Chemical Structure
  28. GC60589 Apalutamide D4 Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. Apalutamide D4  Chemical Structure
  29. GC64540 Ar-V7-IN-1 Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications, in particular cancers such as prostate cancer (extracted from patent WO2018114781A1, compound 43). Ar-V7-IN-1  Chemical Structure
  30. GC16840 ARN-509 ARN-509 (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. ARN-509  Chemical Structure
  31. GC62118 ARV-110 ARV-110 (ARV-110) is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer. ARV-110  Chemical Structure
  32. GC10547 ASC-J9 A selective enhancer of AR degradation ASC-J9  Chemical Structure
  33. GC66207 Atraric acid Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases. Atraric acid  Chemical Structure
  34. GC10372 AZD3514 Androgen receptor downregulator AZD3514  Chemical Structure
  35. GC12271 Bicalutamide Androgen receptor antagonist Bicalutamide  Chemical Structure
  36. GC46925 Bicalutamide-d4 An internal standard for the quantification of bicalutamide Bicalutamide-d4  Chemical Structure
  37. GC31577 Bifluranol (BX341) Bifluranol (BX341) (BX341) is an anti-androgen. Bifluranol (BX341)  Chemical Structure
  38. GC35534 BMS-564929 BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM. BMS-564929  Chemical Structure
  39. GC41187 Boldenone Cypionate Boldenone is an anabolic androgenic steroid and synthetic derivative of testosterone that was originally developed for veterinary use. Boldenone Cypionate  Chemical Structure
  40. GC35541 Boldenone Undecylenate Boldenone Undecylenate  Chemical Structure
  41. GC17491 CITCO

    Constitutive androstane receptor (CAR) agonist

    CITCO  Chemical Structure
  42. GC14560 Cl-4AS-1 steroidal androgen receptor agonist Cl-4AS-1  Chemical Structure
  43. GC62209 CLP-3094 CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094  Chemical Structure
  44. GC47159 Cyprodinil An anilinopyrimidine fungicide Cyprodinil  Chemical Structure
  45. GC13971 Cyproterone Acetate Androgen receptor antagonist Cyproterone Acetate  Chemical Structure
  46. GC10785 Danazol A derivative of testosterone and ethisterone Danazol  Chemical Structure
  47. GC11070 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body . Dehydroepiandrosterone (DHEA)  Chemical Structure
  48. GC34005 Dehydroisoandrosterone 3-acetate (Dehydroepiandrosterone 3-acetate) Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression. Dehydroisoandrosterone 3-acetate (Dehydroepiandrosterone 3-acetate)  Chemical Structure
  49. GC47215 Dienogest-d8 An internal standard for the quantification of dienogest Dienogest-d8  Chemical Structure
  50. GC47231 Dimethomorph A morpholine fungicide Dimethomorph  Chemical Structure
  51. GC31441 DJ-V-159 DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A). DJ-V-159  Chemical Structure
  52. GC49648 Enobosarm-d4 An internal standard for the quantification of enobosarm Enobosarm-d4  Chemical Structure
  53. GC64854 Enzalutamide-d3 Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide-d3  Chemical Structure
  54. GC16631 EPI-001 AR antagonist EPI-001  Chemical Structure
  55. GC13072 Epiandrosterone steroid hormone with weak androgenic activity Epiandrosterone  Chemical Structure
  56. GC11796 Estradiol valerate Estradiol valerate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy drugs. Estradiol valerate  Chemical Structure
  57. GC49563 Fenhexamid Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid  Chemical Structure
  58. GC10618 Fluoxymesterone androgen receptor agonist Fluoxymesterone  Chemical Structure
  59. GC12126 Flutamide Androgen receptor antagonists Flutamide  Chemical Structure
  60. GC48831 Flutamide-d7 An internal standard for the quantification of flutamide Flutamide-d7  Chemical Structure
  61. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM  Chemical Structure
  62. GC30086 GLPG0492 A selective androgen receptor modulator GLPG0492  Chemical Structure
  63. GC30101 GLPG0492 R enantiomer GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator. GLPG0492 R enantiomer  Chemical Structure
  64. GC17679 GSK2881078 selective androgen receptor modulator (SARM) GSK2881078  Chemical Structure
  65. GC14221 HE-3235 HE-3235, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. HE-3235 is active in rodent models of prostate and breast cancer. HE-3235  Chemical Structure
  66. GC62249 Honokiol DCA Honokiol DCA  Chemical Structure
  67. GC36344 Isosilybin B Isosilybin B, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation. Isosilybin B  Chemical Structure
  68. GC62106 JNJ-63576253 JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC). JNJ-63576253  Chemical Structure
  69. GC18496 Leelamine (hydrochloride) Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine (hydrochloride)  Chemical Structure
  70. GC47554 Letrozole-d4 An internal standard for the quantification of letrozole Letrozole-d4  Chemical Structure
  71. GC32403 LGD-3303

    LGD-3303 is a selective androgen receptor modulator (SARM).

    LGD-3303  Chemical Structure
  72. GC32408 LGD-4033 An Analytical Reference Standard LGD-4033  Chemical Structure
  73. GC63579 Linuron Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron  Chemical Structure
  74. GN10142 Lupeol Lupeol  Chemical Structure
  75. GC31380 LY2452473

    LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).

    LY2452473  Chemical Structure
  76. GC12385 MDV3100 (Enzalutamide)

    A non-steroidal androgen receptor antagonist

    MDV3100 (Enzalutamide)  Chemical Structure
  77. GC12974 Medroxyprogesterone acetate

    Steroidal progestin

    Medroxyprogesterone acetate  Chemical Structure
  78. GC61850 Medroxyprogesterone acetate D3 Medroxyprogesterone acetate D3  Chemical Structure
  79. GC63066 Methenolone acetate Methenolone acetate  Chemical Structure
  80. GC11837 MI-136 menin-MLL interaction inhibitor MI-136  Chemical Structure
  81. GC36621 MK-0773 MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM. MK-0773  Chemical Structure
  82. GC32907 N-desmethyl Enzalutamide (N-desmethyl MDV 3100) N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide (N-desmethyl MDV 3100) demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide. N-desmethyl Enzalutamide (N-desmethyl MDV 3100)  Chemical Structure
  83. GC64586 Nandrolone laurate Nandrolone laurate  Chemical Structure
  84. GC63096 Nandrolone phenylpropionate Nandrolone phenylpropionate  Chemical Structure
  85. GC44363 Neoaureothin Neoaureothin is a bacterial metabolite that has been found in Streptomyces. Neoaureothin  Chemical Structure
  86. GC44405 Nilutamide Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. Nilutamide  Chemical Structure
  87. GC11386 ODM-201 ODM-201 (ODM-201;BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay. ODM-201  Chemical Structure
  88. GC32402 ORM-15341 ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. ORM-15341  Chemical Structure
  89. GC36820 Ostarine Ostarine  Chemical Structure
  90. GC44527 p,p'-DDE p,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. p,p'-DDE  Chemical Structure
  91. GC12938 PF 998425 non-steroidal androgen receptor (AR) antagonist PF 998425  Chemical Structure
  92. GC48724 Pregnanetriol A metabolite of 17α-hydroxyprogesterone Pregnanetriol  Chemical Structure
  93. GC44686 Prochloraz Prochloraz is an imidazole antifungal that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Prochloraz  Chemical Structure
  94. GC36981 PROTAC AR Degrader-4 PROTAC AR Degrader-4  Chemical Structure
  95. GC61481 PROTAC AR Degrader-4 TFA PROTAC AR Degrader-4 TFA  Chemical Structure
  96. GC33224 Proxalutamide (GT0918) Proxalutamide (GT0918) (GT0918) is an orally active potent androgen receptor (AR) antagonist. Proxalutamide (GT0918) (GT0918) can be used in the study for prostate cancer and COVID-19. Proxalutamide (GT0918)  Chemical Structure
  97. GC19305 RAD140 RAD140 (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM. RAD140  Chemical Structure
  98. GC62683 Ralaniten Ralaniten (EPI-002) is a potent and orally active antagonist of the androgen receptor-N-terminal domain (AR-NTD). Ralaniten inhibits AR transcriptional activity, with IC50 of 7.4 μM. Ralaniten can be used for the research of castration-resistant prostate cancer (CRPC). Ralaniten  Chemical Structure
  99. GC62603 Ralaniten triacetate Ralaniten triacetate (EPI-506), the pro-drug of Ralaniten, is a first-in-class, orally active androgen receptor (AR) N-terminal domain (NTD) inhibitor. Ralaniten triacetate shows activity against both full length and resistance-related AR species, including AR-v7. Ralaniten triacetate  Chemical Structure
  100. GC11957 RD162

    androgen receptor (AR) antagonist

    RD162  Chemical Structure
  101. GC63402 Rezvilutamide Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer. Rezvilutamide  Chemical Structure

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