Estrogen/progestogen Receptor
The estrogen/progestogen receptors are activated by the hormone estrogen/progesterone and regulate the gene transcription.
Products for Estrogen/progestogen Receptor
- Cat.No. Product Name Information
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GC11282
β-Estradiol
Sex hormone
- GC15975 α-Estradiol α-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
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GC41671
(±)-Equol 4'-sulfate (sodium salt)
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
- GC15373 (E)-2-Decenoic acid An unsaturated fatty acid found in royal jelly
- GC49189 (E/Z)-4-hydroxy Tamoxifen-d5 An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
- GC40833 (E/Z)-Endoxifen (E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6.
- GC13373 (R)-DPN estrogen receptor (ER) β agonist
- GC18003 (R,R)-THC ERα receptor agonist
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GC49520
(S)-Equol
An estrogen receptor β agonist
- GC16372 (Z)-4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen. (Z)-4-Hydroxytamoxifen shows higher affinity for the ER than Tamoxifen. (Z)-4-Hydroxytamoxifen induces a non-apoptotic cytotoxic effect in human endometrial adenocarcinoma cells.
- GC49161 16α-hydroxy Dehydroepiandrosterone A metabolite of dehydroepiandrosterone
- GC41950 16α-hydroxy Estrone The naturally-occurring estrogens are estrone, estradiol, and estriol.
- GC49068 16-Epiestriol A metabolite of estrone
- GC49848 16-Ketoestradiol An active metabolite of estrone
- GC46470 17β-Estradiol-d2 17β-Estradiol-d2 (β-17β-Estradiol-d2) is the deuterium labeled Estradiol.
- GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane.
- GC48819 17-Epiestriol A metabolite of estrone
- GC17475 17-Hydroxyprogesterone An endogenous progestogen and chemical intermediate
- GC18635 18-hydroxy-11-deoxy Corticosterone 18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland.
- GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase
- GC49172 2-hydroxy Estrone An active metabolite of estrone
- GC48910 2-Hydroxyanthraquinone An anthraquinone with antibacterial and estrogenic activities
- GC18462 3-Formylsalicylic Acid 3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone.
- GC48824 4-hydroxy Estrone A metabolite of estrone
- GC17803 4-Hydroxytamoxifen 4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. 4-Hydroxytamoxifen is an estrogen receptor modulator.
- GC49562 4-methoxy Estrone An active metabolite of estrone
- GC11606 4-Methylbenzylidene camphor ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.
- GC42473 4-tert-Octylphenol diethoxylate 4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X.
- GC52365 4-tert-Octylphenol monoethoxylate An alkylphenolethoxylate and a degradation product of non-ionic surfactants
- GC13917 4’-hydroxy Tamoxifen metabolite of tamoxifen, an estrogen receptor modulator
- GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone
- GC49391 7α-Thiospironolactone An active metabolite of spironolactone
- GC17119 8-Prenylnaringenin estrogen receptor inhibitor
- GC50091 AC 186 Potent and selective ERβ agonist; neuroprotective
- GC13297 Altrenogest Progestogen receptor agonist
- GC14405 AZD9496 estrogen receptor inhibitor, orally active
- GC17588 Bavachin estrogen receptors ERα and ERβ activator
- GC14883 Bazedoxifene
- GC10852 Bazedoxifene acetate A selective estrogen receptor modulator
- GC10245 Bazedoxifene HCl Bazedoxifene HCl (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene HCl can be used for the research of osteoporosis. Bazedoxifene HCl acts as an inhibitor of IL-6/GP130 protein-protein interactions. Bazedoxifene HCl can be used for the research of pancreatic cancer.
- GC49757 Bazedoxifene N-oxide An oxidative degradation product of bazedoxifene
- GC46907 Bazedoxifene-d4 An internal standard for the quantification of bazedoxifene
- GC11144 Chlormadinone acetate steroidal progestin with additional antiandrogen and antigonadotropic effects
- GC10012 Chlorotrianisene Estrogen agonist
- GC15366 Clomiphene citrate Selective estrogen receptor modulator
- GC10002 Coumestrol competitive binder of the estrogen receptors ERα
- GC45413 Cridanimod (sodium salt)
- GC10180 Cyclofenil Non-steroidal selective estrogen receptor modulator (SERM)
- GC47168 Daidzein-d4 An internal standard for the quantification of daidzein
- GC49025 Desogestrel-13C2-d2 An internal standard for the quantification of desogestrel
- GC17688 Diarylpropionitrile(DPN) Diarylpropionitrile(DPN) (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM.
- GC15578 Dienogest Orally active synthetic progesterone
- GC47215 Dienogest-d8 An internal standard for the quantification of dienogest
- GC10663 Dihydrodaidzein estrogen receptor agonist
- GC12379 Drospirenone Synthetic progestin
- GC52420 Drospirenone-13C3 An internal standard for the quantification of drospirenone
- GC12140 Endoxifen Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).
- GC18333 Equilenin Equilenin is an equine estrogen found in the urine of pregnant mares.
- GC16292 Equol non-steroidal estrogen
- GC10389 ERB 041 ERB 041 (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. ERB 041 displays >200-fold selectivity for ERβ over ERα. ERB 041 is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. ERB 041 induces ovarian cancer apoptosis.
- GC11822 Erteberel (LY500307) Erteberel (LY500307) (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively.
- GC47309 Estetrol (hydrate) A naturally occurring estrogen
- GC48979 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) A substrate of multidrug resistance protein 2
- GC43629 Estradiol 3-sulfate 17β-Glucuronide (potassium salt) Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol, and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma.
- GC10139 Estradiol Cypionate Estrogen receptor inhibitor
- GC12182 Estriol Estrogen receptor antagonist
- GC45450 Estriol-d2 Estriol-d2 is the deuterium labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
- GC14385 Estrone Estrogenic hormone
- GC45451 Estrone 3-methyl ether
- GC43631 Estrone 3-sulfate (sodium salt) Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer.
- GC49254 Estrone-3-Glucuronide (sodium salt hydrate) A metabolite of 17β-estradiol
- GC45452 Estrone-d2
- GC16852 Estropipate Estrogen receptor agonist
- GC12148 Ethinyl Estradiol Ethinyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.
- GC11436 Ethisterone Progestogen hormone
- GC12000 Ethynodiol diacetate Progestogen receptor agonist
- GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) A metabolite of ethynyl estradiol
- GC13303 Etonogestrel steroidal progestin
- GC49563 Fenhexamid Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor.
- GC14131 FERb 033 ERβ receptor agonist
- GC18641 Ferutinin Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM).
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GC18000
Fulvestrant (ICI 182,780)
Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades ER, then inhibits ER-mediated transcriptional activity with an IC50 of 9.4 nM.
- GC49878 Fulvestrant 9-sulfone An estrogen receptor antagonist and a derivative of fulvestrant
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GC12766
G-1
G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM.
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GC16618
G-15
A GPER receptor antagonist
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GC14902
G-36
GPER activator
- GC10017 Gestodene Progestogen hormonal contraceptive
- GC48763 Gestodene-d6 An internal standard for the quantification of gestodene
- GC10558 GSK 4716 estrogen-related receptors ERRβ and ERRγ agonist
- GC15324 Hexestrol Estrogen receptor agonist
- GC15599 Hydroxyprogesterone caproate synthetic progestational agent
- GC44036 Lasofoxifene Lasofoxifene is a third-generation, non-steroidal selective estrogen receptor modulator (SERM).
- GC11425 Lasofoxifene (tartrate) third-generation, non-steroidal selective estrogen receptor modulator (SERM)
- GC47554 Letrozole-d4 An internal standard for the quantification of letrozole
- GC14704 Levonorgestrel Estrogen/progestogen receptor agonist
- GC11781 Medroxyprogesterone potent progesterone receptor agonist
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GC12974
Medroxyprogesterone acetate
Steroidal progestin
- GC11688 Megestrol Acetate Anti-estrogen agent
- GC25627 Menotropin Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.
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GC17161
Methylpiperidino pyrazole
ERα selective antagonist