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Home >> Signaling Pathways >> Endocrinology and Hormones >> RAAS

RAAS

RAAS (renin-angiotensin-aldosterone system) is a hormonal signaling cascade that regulates blood pressure, systemic vascular resistance, sodium balance, fluid volume and tissue perfusion etc. It is associated with hypertension, kidney failure and congestive heart failure etc.

Products for  RAAS

  1. Cat.No. Product Name Information
  2. GC16978 Candesartan

    Candesartan M1, CV-11974

     Angiotensin II receptor 1 (AT1) antagonist Candesartan Chemical Structure
  3. GC16223 Captopril

    SA 333, SQ 14,225

     An ACE inhibitor Captopril Chemical Structure
  4. GC13078 Imidapril HCl

    TA-6366

     Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril HCl Chemical Structure
  5. GC10257 Losartan Potassium (DuP 753)

    DuP753, MK 954

     Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM. Losartan Potassium (DuP 753) Chemical Structure
  6. GC15166 Perindopril Erbumine ACE inhibitor Perindopril Erbumine Chemical Structure
  7. GC15736 Rosuvastatin Calcium

    ZD 4522

     HMG-CoA reductase inhibitor Rosuvastatin Calcium Chemical Structure
  8. GC15023 Telmisattan

    BIBR 277, Micardis, Pritor

     Telmisattan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM. Telmisattan Chemical Structure

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