Histone Deacetylation
Products for Histone Deacetylation
- Cat.No. Product Name Information
- GC46628 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline A building block and synthetic intermediate
- GC46736 7-Bromoheptanoic Acid A building block
- GC48986 9-hydroxy Stearic Acid A hydroxy fatty acid
- GC48382 Ac-QPKK(Ac)-AMC A fluorogenic substrate for SIRT1, SIRT2, and SIRT3
- GC48775 AES-350 An inhibitor of class I and class IIb HDACs
- GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid
- GC40674 APHA Compound 8 A class I and II HDAC inhibitor
- GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid
- GC18408 BML-278 BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 uM.
-
GC11641
Boc-Lys(Ac)-AMC
GPCR G2A/GPR132 agonist
- GC48620 BPKDi A PKD inhibitor
- GC40923 BRD4884 BRD4884 is an HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3, respectively.
- GC46104 Butyric Acid-d7 An internal standard for the quantification of sodium butyrate
- GC43147 CAY10398 CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 μM.
- GC41601 CAY10591 CAY10591 is a potent activator of Sirt1 and suppresses TNF-α in a dose-dependent manner.
- GC43201 CAY10722 CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 μM).
- GC49029 CAY17c An inhibitor of BRD4 and class I and class IIb HDACs
-
GC43318
coumarin-SAHA
Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access.
- GC52368 DL-Sulforaphane Glutathione A metabolite of sulforaphane
- GC43806 HC Toxin HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM).
- GC41495 HDAC3 Inhibitor HDAC3 Inhibitor (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM.
- GC49693 HDAC5 (human, recombinant) Active, pure human recombinant enzyme
- GC47579 L-Pyrohomoglutamic Acid An amino acid building block
- GC52188 MDL 800
- GC48805 Methapyrilene (hydrochloride) An H1 receptor antagonist and non-genotoxic carcinogen
- GC49270 Nicotinamide-d4 An internal standard for the quantification of nicotinamide
- GC52166 NN-390 NN-390 is a potent and selective HDAC6 inhibitor, with an IC50 of 9.8 nM. NN-390 penetrates the blood-brain barrier (BBB). NN-390 shows study potential in metastatic Group 3 MB (medulloblastoma).
- GC48460 NR-160 An inhibitor of HDAC6
- GC49815 Oleuropein aglycone A polyphenol with diverse biological activities
- GC44865 SAHA-BPyne Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access.
- GC44866 SAHA-d5 SAHA-d5 (SAHA-d5) is the deuterium labeled Vorinostat.
- GC48084 Sodium 4-Phenylbutyrate-d11 Phenylbutyrate-d11 (sodium) is deuterium labeled Sodium 4-phenylbutyrate. Sodium 4-phenylbutyrate (4-PBA sodium) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.
- GC46226 SS-208 An HDAC6 inhibitor
- GC18915 Trapoxin A Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor.
- GC45080 Trichostatin C Trichostatin C is a glycosylated derivative of trichostatin A, the antifungal antibiotic that reversibly inhibits histone deacetylase.
- GC45095 Tubastatin A (trifluoroacetate salt) Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM.
- GC48408 TW9 A dual inhibitor of BRD4 and HDAC1
- GC45137 Valproic Acid Acyl-D-Glucuronide Valproic acid acyl-D-glucuronide is the major urinary metabolite of valproic acid.