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Home >> Signaling Pathways >> GPCR/G protein >> Angiotensin Receptor

Angiotensin Receptor

The angiotensin receptors are seven-membrane G-protein-coupled receptors. They mediate the cardiovascular and other effects of angiotensin II which is a bioactive peptide of the renin–angiotensin system.

Products for  Angiotensin Receptor

  1. Cat.No. Product Name Information
  2. GA20291 (Sar¹)-Angiotensin II (Sar¹)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar¹)-Angiotensin II Chemical Structure
  3. GC17757 1H-1-ethyl Candesartan Cilexetil selective angiotensin II type 1 receptor (AT1) antagonist 1H-1-ethyl Candesartan Cilexetil Chemical Structure
  4. GC14445 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine nonpeptidic angiotensin II receptor antagonist 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine Chemical Structure
  5. GC11004 A 779 A 779 is a potent and selective angiotensin-(1-7)/Mas receptor antagonist with an IC50 value of 0.3nM. A 779 Chemical Structure
  6. GC32674 A81988 (Abbott81988)

    Abbott81988

     A81988 (Abbott81988) is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors. A81988 (Abbott81988) Chemical Structure
  7. GC72137 Aclerastide Aclerastide (DSC-127) is an angiotensin receptor agonist. Aclerastide Chemical Structure
  8. GC10146 AHU-377(Sacubitril)

    Sacubitril

     AHU-377(Sacubitril) (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. AHU-377(Sacubitril) Chemical Structure
  9. GC68638 Allisartan isoproxil

    Allisartan isoproxil (ALS-3) is an orally effective, selective, non-peptide inhibitor of the angiotensin II type 1 receptor. It is also a blood pressure-lowering agent that may inhibit the renin-angiotensin-aldosterone system and oxidative stress. Allisartan isoproxil can lower blood pressure and protect organs to prevent cerebral vascular damage. However, in rat models at doses of 80-320 mg/kg/day, it has shown toxicity targeting liver organs.

     Allisartan isoproxil Chemical Structure
  10. GP10077 Angiotensin (1-7)

    Asp-Arg-Val-Tyr-Ile-His-Pro

    Ang-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively[1].

     Angiotensin (1-7) Chemical Structure
  11. GC61496 Angiotensin (1-7) (acetate)

    Ang-(1-7) (acetate)

     Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin (1-7) (acetate) Chemical Structure
  12. GA20760 Angiotensin A (1-7) Angiotensin A (1-7), a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Angiotensin A (1-7) Chemical Structure
  13. GC12671 Angiotensin Fragment 1-7 (acetate) type 1 angiotensin II receptor agonist Angiotensin Fragment 1-7 (acetate) Chemical Structure
  14. GC72130 Angiotensin I/II (1-5) (TFA) Angiotensin I/II 1-5 TFA is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I/II (1-5) (TFA) Chemical Structure
  15. GC61952 Angiotensin I/II (1-6) (TFA) Angiotensin I/II (1-6) TFA contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. Angiotensin I/II (1-6) (TFA) Chemical Structure
  16. GC35351 Angiotensin II (1-4), human

    Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE).

     Angiotensin II (1-4), human Chemical Structure
  17. GC35352 Angiotensin II (3-8), human

    Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.

     Angiotensin II (3-8), human Chemical Structure
  18. GC35353 Angiotensin II (3-8), human TFA

    Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT1 receptor.

     Angiotensin II (3-8), human TFA Chemical Structure
  19. GC42810 Angiotensin II (5-8) (human, rat, mouse) Angiotensin II (5-8) (human, rat, mouse) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Angiotensin II (5-8) (human, rat, mouse) Chemical Structure
  20. GC35354 Angiotensin II 5-valine

    Angiotensin II 5-valine is an agonist of angiotensin receptor.

     Angiotensin II 5-valine Chemical Structure
  21. GC60584 Angiotensin II human acetate

    Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system.

     Angiotensin II human acetate Chemical Structure
  22. GC62844 Angiotensin II human TFA

    Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA

    Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system.

     Angiotensin II human TFA Chemical Structure
  23. GC35355 Angiotensin III Angiotensin III Chemical Structure
  24. GP10110 Angiotensin III (human, mouse) An agonist at AT1 and AT2 receptors Angiotensin III (human, mouse) Chemical Structure
  25. GC35356 Angiotensin III TFA Angiotensin III TFA Chemical Structure
  26. GC66025 Angiotensin III, human, mouse TFA Angiotensin III, human, mouse (TFA) is an angiotensin. Angiotensin III, human, mouse TFA Chemical Structure
  27. GC12065 AVE 0991 AVE 0991 is a Nonpeptide Mimic of the Effects of Angiotensin-(1-7) on the Endothelium. AVE 0991 Chemical Structure
  28. GC17686 AVE 0991 sodium salt Ang-(1-7) receptor Mas agonist AVE 0991 sodium salt Chemical Structure
  29. GC13277 Azilsartan

    TAK-536

     Potent angiotensin II type 1 (AT1) receptor inverse agonist Azilsartan Chemical Structure
  30. GC35452 Azilsartan D5 Azilsartan D5 (TAK-536 D5) is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist. Azilsartan D5 Chemical Structure
  31. GC11407 Azilsartan Medoxomil

    TAK-491

    Angiotensin II receptor type 1 antagonist

     Azilsartan Medoxomil Chemical Structure
  32. GC10642 Azilsartan medoxomil monopotassium

    Angiotensin II receptor type 1 antagonist

     Azilsartan medoxomil monopotassium Chemical Structure
  33. GC66468 Azilsartan mepixetil Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A). Azilsartan mepixetil Chemical Structure
  34. GC66440 Azilsartan mopivabil Azilsartan mopivabil is the potent antagonist of angiotensin II receptor. Azilsartan mopivabil Chemical Structure
  35. GC45390 Benazepril Acyl-β-D-Glucuronide

    Benazapril Glucuronide

       Benazepril Acyl-β-D-Glucuronide Chemical Structure
  36. GC46913 Benazepril-d5 (hydrochloride)

    CGS 14824A-d5

     An internal standard for the quantification of benazapril Benazepril-d5 (hydrochloride) Chemical Structure
  37. GC19071 BIBS 39 BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. BIBS 39 Chemical Structure
  38. GC60095 Brain Natriuretic Peptide (1-32), rat acetate

    BNP (1-32), rat acetate

     Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). Brain Natriuretic Peptide (1-32), rat acetate Chemical Structure
  39. GC32589 Brain Natriuretic Peptide (BNP) (1-32), rat Brain Natriuretic Peptide (BNP) (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). Brain Natriuretic Peptide (BNP) (1-32), rat Chemical Structure
  40. GC12034 C-type natriuretic peptide (1-22) (human, rat, swine) C-type natriuretic peptide (1-22) (human, rat, swine) is an endogenous peptide found in plasma and cerebrospinal fluid. C-type natriuretic peptide (1-22) (human, rat, swine) Chemical Structure
  41. GC35756 C-Type Natriuretic Peptide (1-53), human C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide (1-53), human Chemical Structure
  42. GC68908 C-Type Natriuretic Peptide (1-53), human TFA

    C-Type Natriuretic Peptide (1-53), human TFA is a fragment of C-type natriuretic peptide consisting of amino acids 1 to 53. C-Type Natriuretic Peptide TFA belongs to the family of natriuretic peptides and is involved in maintaining electrolyte-fluid balance and vascular tone.

     C-Type Natriuretic Peptide (1-53), human TFA Chemical Structure
  43. GC16978 Candesartan

    Candesartan M1, CV-11974

     Angiotensin II receptor 1 (AT1) antagonist Candesartan Chemical Structure
  44. GC12318 Candesartan Cilexetil

    Candesartan M1 Cilexetil, TCV116

     Prodrug of the angiotensin II receptor 1 (AT1) antagonist candesartan Candesartan Cilexetil Chemical Structure
  45. GC40238 Candesartan-d4

    Candesartan M1-d4

     Candesartan-d4 is intended for use as an internal standard for the quantification of candesartan by GC- or LC-MS. Candesartan-d4 Chemical Structure
  46. GC71621 Candesartan-d5 Candesartan-d5 is the deuterium labeled Candesartan. Candesartan-d5 Chemical Structure
  47. GC15406 CGP 42112

    CGP42112A

     angiotensin AT2 receptor ligand CGP 42112 Chemical Structure
  48. GC32561 CGP48369 CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research. CGP48369 Chemical Structure
  49. GC60748 Dehydro Olmesartan Dehydro Olmesartan is a derivative of Olmesartan. Dehydro Olmesartan Chemical Structure
  50. GC43580 DX600 DX600 is a potent and selective peptide inhibitor of angiotensin-converting enzyme 2 (ACE2; Kis = 2.8, 200, and 1,200 nM for recombinant, human, and murine ACE2, respectively). DX600 Chemical Structure
  51. GC49566 DX600 (trifluoroacetate salt) A peptide inhibitor of ACE2 DX600 (trifluoroacetate salt) Chemical Structure
  52. GC32536 Elisartan (HN 65021)

    HN 65021

     Elisartan (HN 65021) is an orally active non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. Elisartan (HN 65021) Chemical Structure
  53. GC19137 EMA401

    EMA401; PD-126055

     EMA401 (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. EMA401 Chemical Structure
  54. GC13436 EMD 66684 angiotensin AT1 receptor antagonist EMD 66684 Chemical Structure
  55. GC43601 Enalaprilat (hydrate) Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat (hydrate) Chemical Structure
  56. GC16297 Eprosartan Mesylate

    SKF 108566J

     Angiotensin AT1 receptor antagonists Eprosartan Mesylate Chemical Structure
  57. GC36046 Fimasartan Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Fimasartan Chemical Structure
  58. GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril Fosinopril-d7 (sodium salt) Chemical Structure
  59. GC63298 Ganoderic acid N Ganoderic acid N is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid N Chemical Structure
  60. GC49228 Ganoderol B

    Ganodermadiol, (+)-Ganoderol B

     A triterpenoid with diverse biological activities Ganoderol B Chemical Structure
  61. GC46155 H-Ile-Pro-Pro-OH (trifluoroacetate salt)

    IPP

     A neuropeptide with diverse biological activities H-Ile-Pro-Pro-OH (trifluoroacetate salt) Chemical Structure
  62. GC31529 H-Val-Pro-Pro-OH H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. H-Val-Pro-Pro-OH Chemical Structure
  63. GC47438 H-Val-Pro-Pro-OH (trifluoroactetate salt)

    VPP

     A neuropeptide with diverse biological activities H-Val-Pro-Pro-OH (trifluoroactetate salt) Chemical Structure
  64. GC34326 H-Val-Pro-Pro-OH TFA H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. H-Val-Pro-Pro-OH TFA Chemical Structure
  65. GC10467 Irbesartan

    BMS 186295, SR 47436

     Angiotensin II inhibitor Irbesartan Chemical Structure
  66. GC40208 Irbesartan-d4 Irbesartan-d4 is intended for use as an internal standard for the quantification of irbesartan by GC- or LC-MS. Irbesartan-d4 Chemical Structure
  67. GC32569 L-159282 (MK 996)

    MK 996

     L-159282 (MK 996) is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity. L-159282 (MK 996) Chemical Structure
  68. GC30443 L162389 L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM. L162389 Chemical Structure
  69. GC31567 L162441 L162441 is an Angiotensin type 1 receptor antagonist. L162441 Chemical Structure
  70. GC11784 LCZ696 LCZ696 (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure. LCZ696 Chemical Structure
  71. GC45501 Lisinopril-d5   Lisinopril-d5 Chemical Structure
  72. GC10249 Losartan

    Angiotensin II receptor antagonist

     Losartan Chemical Structure
  73. GC12512 Losartan Carboxylic Acid

    E-3174,EXP-3174

     AT1 antagonist Losartan Carboxylic Acid Chemical Structure
  74. GC36480 Losartan D4 An internal standard for the quantification of losartan Losartan D4 Chemical Structure
  75. GC36481 Losartan D4 Carboxylic Acid Losartan D4 Carboxylic Acid (E-3174 D4) is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist. Losartan D4 Carboxylic Acid Chemical Structure
  76. GC10257 Losartan Potassium (DuP 753)

    DuP753, MK 954

     Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM. Losartan Potassium (DuP 753) Chemical Structure
  77. GC32632 LY285434 LY285434 is a suitable angiotensin II receptor antagonist. LY285434 Chemical Structure
  78. GC64604 Mopivabil Mopivabil is the antagonist of angiotensin II receptor. Mopivabil Chemical Structure
  79. GC10024 Novokinin Angiotensin AT2 receptor agonist Novokinin Chemical Structure
  80. GC16936 Olmesartan

    CS 088, RNH 6270

     An AT1 receptor antagonist and active metabolite of olmesartan medoxomil Olmesartan Chemical Structure
  81. GC36802 Olmesartan D4 Olmesartan D4 (RNH-6270 D4) is the deuterium labeled Olmesartan. Olmesartan D4 Chemical Structure
  82. GC16752 Olmesartan medoxomil

    CS 866

     A prodrug form of olmesartan Olmesartan medoxomil Chemical Structure
  83. GC61153 Olmesartan medoxomil impurity C Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil impurity C Chemical Structure
  84. GC61154 Olmesartan methyl ester Olmesartan methyl ester is an intermediate in the synthesis of Olmesartan medoxomil. Olmesartan methyl ester Chemical Structure
  85. GC17384 PD 123319 ditrifluoroacetate A selective angiotensin II type 2 receptor antagonist PD 123319 ditrifluoroacetate Chemical Structure
  86. GC16394 PD123319

    (S)-(+)-PD 123319

     PD123319 is a non-peptide inhibitor of angiotensin II receptor with IC50 value of 34nM . PD123319 Chemical Structure
  87. GC16871 Perindopril ACE inhibitor Perindopril Chemical Structure
  88. GC32530 Pratosartan (FW 7203)

    FW 7203; KD 3-671; KT 3671

     Pratosartan (FW 7203) is a selective angiotensin II receptor antagonist. Pratosartan (FW 7203) Chemical Structure
  89. GC48513 Quinapril-d5

    CI-906-d5

     An internal standard for the quantification of quinapril Quinapril-d5 Chemical Structure
  90. GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Chemical Structure
  91. GC49408 Ramipril Diketopiperazine Acid

    Ramipril Impurity K, Ramipril IK

     A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Acid Chemical Structure
  92. GC39821 Saralasin TFA

    [Sar1,Ala8] Angiotensin II TFA

     Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA Chemical Structure
  93. GC32591 SL910102 SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. SL910102 Chemical Structure
  94. GC32479 Sparsentan (RE-021) Sparsentan (RE-021) (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. Sparsentan (RE-021) Chemical Structure
  95. GC32507 Tasosartan (WAY-ANA 756)

    WAY-ANA-756

     Tasosartan (WAY-ANA 756) is a long-acting angiotensin II (AngII) receptor antagonist. Tasosartan (WAY-ANA 756) Chemical Structure
  96. GC38856 TD-0212 TFA TD-0212 TFA is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. TD-0212 TFA Chemical Structure
  97. GC15023 Telmisattan

    BIBR 277, Micardis, Pritor

     Telmisattan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM. Telmisattan Chemical Structure
  98. GC18202 Temocaprilat

    CS 622 Diacid, RS 5139, Temocapril Diacid

     An ACE inhibitor Temocaprilat Chemical Structure
  99. GC46233 Trandolaprilat (hydrate)

    RU 44403

     Trandolaprilat (hydrate) is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilat (hydrate) Chemical Structure
  100. GC13389 Tranilast

    3,4-DAA, N(3',4'Dimethyoxycinnamoyl) Anthranilic Acid, N-5', MK 341, SB 252218

     Angiogenesis inhibitor Tranilast Chemical Structure
  101. GC12443 Tranilast Sodium Antiallergic agent Tranilast Sodium Chemical Structure

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