OX Receptor
OX receptor (orexin receptor) is a G-protein coupled receptor that is involved in the regulation of feeding behaviour.
Products for OX Receptor
- Cat.No. Product Name Information
- GC16336 ACT 335827 Orexin receptor 1 antagonist,potent and selective
- GC50142 ACT 462206 Potent, dual orexin receptor antagonist
- GC10717 Almorexant OX1R/OX2R antagonist
- GC10050 Almorexant hydrochloride OX1R/OX2R antagonist
- GC65550 Danavorexton Danavorexton is an orexin receptor agonist.
- GC13741 EMPA OX2 receptor antagonist
- GC30832 GSK1059865 GSK1059865 is a potent orexin 1 receptor antagonist.
- GC30829 IPSU An orexin receptor 2 antagonist
- GC14809 JNJ 10397049 OX2 receptor antagonist
- GC63415 JNJ-54717793 JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor (OX1R) antagonist (plasma EC50=85 ng/mL).
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GC19220
Lemborexant
Lemborexant (E2006) is an oral active diorexin receptor antagonist (DORA) and has been approved by the US Food and Drug Administration for the treatment of insomnia.
- GC12242 MK 6096 MK 6096 (MK-6096) is an orally bioavailable potent and selective reversible antagonist of OX1 and OX2 receptor(<3 nM in binding).
- GC19249 MK-1064 MK-1064 is a selective orexin 2 receptor antagonist (2-SORA) for the research of insomnia.
- GC19250 MK-3697 MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.95 nM.
- GC30941 Nemorexant (ACT-541468)
- GC19272 Orexin 2 Receptor Agonist Orexin 2 Receptor Agonist is a potent (EC50 on OX2R is 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio is 70) agonist.
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GC67929
Orexin 2 Receptor Agonist 2
Orexin 2 Receptor Agonist 2 is a selective orexin 2 receptor agonist.
- GC67957 Orexin A (human, rat, mouse) (acetate)
- GC38352 Orexin A (human, rat, mouse) (TFA) Orexin A human, rat, mouse TFA, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes.
- GC14887 Orexin B (human) Endogenous agonist at orexin receptors
- GC16745 Orexin B (mouse) Orexin B (mouse) (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
- GC36812 Orexin B, human TFA Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
- GC64021 Orexin B, rat, mouse TFA Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist.
- GC61770 Orexin receptor antagonist 2 Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78.
- GC65382 Orexin receptor antagonist 5
- GC11818 OXA (17-33) orexin OX1 receptor agonist
- GC13539 SB-334867 Orexin-1 receptor antagonist
- GC15034 SB-334867 free base orexin-1 receptor antagonist, selective
- GC16540 SB-408124 Hydrochloride A potent orexin 1 receptor antagonist
- GC19323 SB-649868 SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).
- GC15534 SB-674042 A potent and selective orexin 1 receptor antagonist
- GC15317 SB408124 OX(1)receptor antagonist
- GC37623 Seltorexant Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R).
- GC17807 TCS 1102 Antagonist for OX2 and OX1 receptors
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GC10549
TCS OX2 29
OX2 receptor antagonist
- GC64826 Vornorexant Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively.
- GC50559 YNT 185 YNT 185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC50s of 0.028 and 2.75 μM for OX2R and OX1R, respectively.
- GC17992 [Ala11,D-Leu15]-Orexin B [Ala11,D-Leu15]-Orexin B is a potent and selective orexin-2 receptor (OX2) agonist.