AP-1

Activator protein 1 (AP-1) is a transcription factor that consist of Jun, Fos, ATF and JDP proteins. It is regulated by cytokines, growth factors, stress signals and infections etc. It is involved in cellular proliferation, transformation and apoptosis.

Products for AP-1

Cat.No. Product Name Information
GC74247 (+)-Glaucarubinone (+)-Glaucarubinone is a potent AP-1 (activator protein-1) inhibitor with an EC50 value of 0.13 µM.
GC74013 FOSL1 degrader 1 FOSL1 degrader 1 (4) is a T-5224-PROTAC, potently degrade FOSL1 (AP-1) to suppress cancer stemness gene expression in HNSCC.
GC71181 Glucocorticoid receptor modulator 1 Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC50 value of 9 nM and 130 nM for NF-κB and AP-1, respectively.
GC72757 SPC 839 SPC 839 (compound 10) is an orally active inhibitor of AP-1 and NF-kB mediated transcriptional activation with IC50 of 0.008 μM.
GC12810 SR 11302 An inhibitor of retinoid-induced AP-1 signaling
GC72363 Timolumab Timolumab (BTT1023 ), a recombinant fully human monoclonal antibody that specifically binds VAP-1.