Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC17213 (S)-AMPA AMPA agonist
- GC17313 (S)-CPW 399 AMPA agonist,subtype-selective,weakly desensitizing
- GC41091 (S)-Lansoprazole (S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 μM), inhibiting gastric acid secretion and increasing intragastric pH.
- GC60418 (S)-Lercanidipine hydrochloride (S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride.
- GC68476 (S)-Nicardipine
- GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
- GC15464 (S)-SNAP 5114 GABA uptake inhibitor
- GC60423 (S)-UFR2709 hydrochloride (S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs.
- GC60425 (S)-Verapamil D7 hydrochloride (S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells.
- GC60008 (S)-Verapamil hydrochloride (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells.
-
GC69979
(S)-VQW-765
(S)-VQW-765 ((S)-AQW-051) is a partial agonist of the α7 nicotinic acetylcholine receptor (nAChR) with oral activity, selectivity and efficacy. It has potential applications in cognitive impairments associated with neurological diseases such as Alzheimer's disease or schizophrenia.
- GC30212 (S)-Willardiine ((-)-Willardiine) (S)-Willardiine ((-)-Willardiine) is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.
- GC35010 (Z)-Capsaicin (Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain.
- GC12927 (±)-Baclofen A GABAB agonist
- GC18603 (±)-Methoxyverapamil (hydrochloride) (±)-Methoxyverapamil (hydrochloride) (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist.
- GC46366 1,2,3,4-Tetrahydro-β-carboline A serotonin reuptake inhibitor and metabolite of tryptamine
- GC61898 1,2,4-Trihydroxybenzene 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes.
- GC45980 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol A triacylglycerol
- GC38726 1,4-Cineole 1,4-Cineole is a widely distributed, natural, oxygenated monoterpene.
- GC49346 1-(3-Chlorophenyl)biguanide (hydrochloride) A 5-HT3 receptor agonist
- GC12863 1-BCP potentiator of AMPA-mediated responses
- GC41990 1-Decanoyl-rac-glycerol 1-Decanoyl-rac-glycerol is a monoacylglycerol that contains decanoic acid at the sn-1 position.
- GC16717 1-EBIO Activator of epithelial KCa channels
- GC39470 1-Octanol 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents.
- GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine A metabolite of carbamazepine and oxcarbazepine
- GC13863 10Panx A peptide inhibitor of PANX1
- GC46047 14-Anhydrodigitoxigenin A cardenolide
-
GC40453
16(R)-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
- GC40454 16(S)-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
- GC40455 17(R)-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
- GC40456 17(S)-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
- GC17223 17-PA GABAA receptor antagonist
- GC46464 17R(18S)-EpETE An EPA metabolite and activator of BKCa channels
- GC60455 2,2,2-Trichloroethanol 2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4).
- GC12469 2,3-Butanedione-2-monoxime 2,3-Butanedione-2-monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor.
-
GC17562
2-APB
2-APB is an antagonist of the Ins(1,4,5)P3 receptor, with an IC50 value of 42μM when the concentration of InsP3 is 100 nm. 2-APB is also an inhibitor of TRPV6 and a modulator of various TRP channels.
- GC49718 2-Chloroadenosine 5-triphosphate (sodium salt) An adenine nucleotide and ATP analog
- GC11267 2-Hydroxysaclofen GABAB receptor antagonist
- GC15416 2-Methylthioadenosine triphosphate tetrasodium salt 2-Methylthioadenosine triphosphate tetrasodium salt is a non-specific P2-receptor agonist.
- GC40377 20-HEPE 20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B.
- GC35075 20-HETE A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC33673 24-Hydroxycholesterol 24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR.
- GC48395 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) is an active form of thyroid hormone.
- GC33703 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifoliaWILLD, with anti-stress effect, prolonging the sleeping time in animals.
- GC11757 3-Bromocytisine α4β4, α4β2 and α7 nACh receptor agonist
- GC35108 3-Deoxyaconitine 3-Deoxyaconitine a diterpenoid alkaloid, is a sodium channel activator.
- GC12506 3-Methyl-GABA GABA aminotransferase activator
- GC42475 4α-Phorbol 12,13-didecanoate 4α-Phorbol 12,13-didecanoate is a negative control for phorbol esters, phorbol 12-myristate 13-acetate and phorbol 12,13-didecanoate (PDD).
- GC49252 4’-hydroxy Trazodone A metabolite of trazodone
- GC17675 4,4-Pentamethylenepiperidine hydrochloride M2 proton channel blocker
-
GC42327
4,9-Anhydrotetrodotoxin
4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes).
- GC68080 4-(Phenyldiazenyl)benzoic acid
- GC33504 4-Acetamidobutanoic acid (N-acetyl GABA) 4-Acetamidobutanoic acid (N-acetyl GABA) (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities.
- GC17469 4-Aminopyridine potassium channel-blocking agent
-
GC42346
4-bromo A23187
4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187.
- GC49575 4-hydroxy Omeprazole sulfide A metabolite of omeprazole
- GC42414 4-hydroxy Tolbutamide 4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker.
- GA20418 4-Hydroxy-hippuric acid Polyphenol metabolite.
- GC18631 4BP-TQS An agonist of α7 subunit-containing nAChRs
- GC16801 5'-Iodoresiniferatoxin TRPV1 (VR1) receptor antagonist
- GC48843 5α-Androst-16-en-3α-ol A pheromone with diverse biological activities
- GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone
- GC16799 5,7-Dichlorokynurenic acid NMDA receptor antagonist
- GC14598 5,7-Dichlorokynurenic acid sodium salt NMDA receptor antagonist
- GC10898 5-(N,N-dimethyl)-Amiloride (hydrochloride) NHE1, NHE2, and NHE3 inhibitor
- GC35147 5-(N,N-Hexamethylene)-amiloride An amiloride derivative with diverse biological activities
- GC60026 5-AAM-2-CP 5-AAM-2-CP is a major metabolite of Acetamiprid.
- GC60027 5-AMAM-2-CP 5-AMAM-2-CP is a major metabolite of Acetamiprid.
- GC13943 5-BDBD P2X4 receptor antagonist
- GC60029 5-Hydroxydecanoate sodium 5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM).
- GC60530 5-Hydroxylansoprazole 5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma.
- GC50179 5J 4 CRAC channel blocker; anti-inflammatory
- GC18176 5α,6β-Dihydroxycholestanol 5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase.
- GC10188 6'-Iodoresiniferatoxin TRPV1 (VR1) vanilloid receptor partial agonist
- GC30943 6,2'-Dihydroxyflavone 6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
- GC11284 6-(4-Methoxyphenyl)-3-pyridazinamine GABAA receptor antagonist
- GC65593 6-Benzoylheteratisine 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine.
- GC13679 6-Iodonordihydrocapsaicin Vanilloid receptor antagonist
- GC31309 6-Methoxy-2-naphthoic acid (Naproxen impurity O) 6-Methoxy-2-naphthoic acid (Naproxen impurity O) is an NMDA receptor modulator extracted from patent WO 2012019106 A2.
- GC30898 6-Methylflavone 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
- GC10781 7-Chlorokynurenic acid NMDA receptor glycine site antagonist
- GC11395 7-Chlorokynurenic acid sodium salt NMDA receptor antagonist acting at the glycine site
- GC13691 7ACC1 MCT inhibitor
- GC14642 7ACC2 MCT inhibitor
- GC10119 8-Bromo-cGMP, sodium salt 8-Bromo-cGMP, sodium salt, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator.
- GC42621 8-bromo-Cyclic ADP-Ribose (sodium salt) Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38.
- GC11483 8-CPT-2Me-cAMP, sodium salt 8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2.
- GC60542 8-Gingerol A natural TRPV1 agonist
- GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
- GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents.
- GC16199 8-pCPT-2-O-Me-cAMP-AM Epac activator
- GC50068 8MDP Potent equilibrative nucleoside transporter (ENT) inhibitor
- GC10392 9-AC Cl- transport inhibitor
- GC10221 9-Phenanthrol TRPM4 blocker
- GC50632 A 1899 Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
- GC50474 A 317491 sodium salt Selective, high affinity P2X3 and P2X2/3 receptor antagonist; antinociceptive
- GC50261 A 425619 Potent TRPV1 antagonist
- GC17212 A 438079 An antagonist of the nucleotide receptor P2X7