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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Products for  Membrane Transporter/Ion Channel

  1. Cat.No. Product Name Information
  2. GC11284 6-(4-Methoxyphenyl)-3-pyridazinamine GABAA receptor antagonist 6-(4-Methoxyphenyl)-3-pyridazinamine Chemical Structure
  3. GC65593 6-Benzoylheteratisine 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine. 6-Benzoylheteratisine Chemical Structure
  4. GC74384 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) (TFA)

    6-FAM-AEEAC-SHK TFA

     6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) TFA (6-FAM-AEEAC-SHK TFA) is a peptide neurotoxin conjugated with a fluorescent marker. 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) (TFA) Chemical Structure
  5. GC13679 6-Iodonordihydrocapsaicin Vanilloid receptor antagonist 6-Iodonordihydrocapsaicin Chemical Structure
  6. GC31309 6-Methoxy-2-naphthoic acid (Naproxen impurity O)

    6-methoxy Naphthalene Acetic Acid, 6-methoxy-2-Naphthylacetic Acid, 6-MNA, NSC 408786

     6-Methoxy-2-naphthoic acid (Naproxen impurity O) is an NMDA receptor modulator extracted from patent WO 2012019106 A2. 6-Methoxy-2-naphthoic acid (Naproxen impurity O) Chemical Structure
  7. GC30898 6-Methylflavone 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone Chemical Structure
  8. GC10781 7-Chlorokynurenic acid

    7-CKA, 7-CTKA, 7-chloro KYNA, NSC 149792

     NMDA receptor glycine site antagonist 7-Chlorokynurenic acid Chemical Structure
  9. GC11395 7-Chlorokynurenic acid sodium salt NMDA receptor antagonist acting at the glycine site 7-Chlorokynurenic acid sodium salt Chemical Structure
  10. GC13691 7ACC1

    Coumarin D 1421, 7-DCCA, 7-Diethylamino-2-oxo-2H-chromen-3-carboxylic Acid

     MCT inhibitor 7ACC1 Chemical Structure
  11. GC14642 7ACC2 MCT inhibitor 7ACC2 Chemical Structure
  12. GC70705 8-Azido-ATP trisodium 8-Azido-ATP (8-N3-ATP) trisodium, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase. 8-Azido-ATP trisodium Chemical Structure
  13. GC90867 8-bromo NAD+ (sodium salt)

    A prodrug form of 8-bromo-cADPR

     8-bromo NAD+ (sodium salt) Chemical Structure
  14. GC10119 8-Bromo-cGMP, sodium salt

    ​​8-bromo-cGMP, 8-bromo Guanosine 3’,5’-cyclic monophosphate

     8-Bromo-cGMP is a cell-permeable cGMP analog that induces PKG activation. 8-Bromo-cGMP, sodium salt Chemical Structure
  15. GC42621 8-bromo-Cyclic ADP-Ribose (sodium salt)

    8-bromo-cADPR, 8-bromo-cADP-Ribose

     Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. 8-bromo-Cyclic ADP-Ribose (sodium salt) Chemical Structure
  16. GC11483 8-CPT-2Me-cAMP, sodium salt

    8-CPT-2MecAMP, 8-pCPTcAMP, 8-pCPT-2′-OMe-cAMP

     8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP, sodium salt Chemical Structure
  17. GC60542 8-Gingerol A natural TRPV1 agonist 8-Gingerol Chemical Structure
  18. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine 8-hydroxy Amoxapine Chemical Structure
  19. GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. 8-Nitroguanine Chemical Structure
  20. GC16199 8-pCPT-2-O-Me-cAMP-AM Epac activator 8-pCPT-2-O-Me-cAMP-AM Chemical Structure
  21. GC50068 8MDP Potent equilibrative nucleoside transporter (ENT) inhibitor 8MDP Chemical Structure
  22. GC10392 9-AC

    9-AC, Anthracene-9-carboxylic Acid, 9-Anthroic Acid, 9-Carboxyanthracene, NSC 151909

     Cl- transport inhibitor 9-AC Chemical Structure
  23. GC10221 9-Phenanthrol

    9-Hydroxyphenanthrene, NSC 50554

     TRPM4 blocker 9-Phenanthrol Chemical Structure
  24. GC50632 A 1899 Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker A 1899 Chemical Structure
  25. GC50474 A 317491 sodium salt Selective, high affinity P2X3 and P2X2/3 receptor antagonist; antinociceptive A 317491 sodium salt Chemical Structure
  26. GC50261 A 425619 Potent TRPV1 antagonist A 425619 Chemical Structure
  27. GC17212 A 438079 An antagonist of the nucleotide receptor P2X7 A 438079 Chemical Structure
  28. GC13733 A 438079 hydrochloride An antagonist of the nucleotide receptor P2X7 A 438079 hydrochloride Chemical Structure
  29. GC17091 A 784168 TRPV1 antagonist,potent and selective A 784168 Chemical Structure
  30. GC17870 A 804598 P2X7 antagonist,potent and selective A 804598 Chemical Structure
  31. GC15434 A 839977 P2X7 antagonist,potent and selective A 839977 Chemical Structure
  32. GC50088 A 85380 dihydrochloride High affinity and selective α4β2 nAChR agonist A 85380 dihydrochloride Chemical Structure
  33. GC14481 A 887826 voltage-dependent Nav1.8 sodium channel blocker A 887826 Chemical Structure
  34. GC11701 A 967079 Selective TRPA1 channel blocker A 967079 Chemical Structure
  35. GC30837 A-1165442 A-1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1. A-1165442 Chemical Structure
  36. GC17710 A-317491

    A 317491;A317491

     A P2X3 and P2X2/3 receptor antagonist A-317491 Chemical Structure
  37. GC35211 A-317491 sodium salt hydrate A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 sodium salt hydrate Chemical Structure
  38. GC11178 A-7 hydrochloride calmodulin antagonist A-7 hydrochloride Chemical Structure
  39. GC11842 A-740003 A selective P2X7 antagonist A-740003 Chemical Structure
  40. GC15701 A-803467 NaV1.8 channel blocker,potent and selective A-803467 Chemical Structure
  41. GC15014 A-867744 A positive allosteric modulator of α7 nAChRs A-867744 Chemical Structure
  42. GC70380 A-935142 A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. A-935142 Chemical Structure
  43. GC11200 A23187

    Calcimycin

    A23187, free acid is a Ca2+ ionophore

     A23187 Chemical Structure
  44. GC39335 A2764 dihydrochloride A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1), which has moderate inhibitory effects on TREK-1 and TALK-1. A2764 dihydrochloride Chemical Structure
  45. GC60545 A2793 A2793 is an efficient dual TWIK-related acid-sensitive K+ channel (TASK)-1/TRESK inhibitor, with an IC50 of 6.8 μM for mTRESK. A2793 Chemical Structure
  46. GC10641 AA 29504 GABAA receptor modulator AA 29504 Chemical Structure
  47. GC50167 AAQ chloride Photoswitchable Kv channel blocker AAQ chloride Chemical Structure
  48. GC68591 ABBV-318

    ABBV-318 is an effective Nav1.7/Nav1.8 blocker, with IC50 values of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8 inhibition, respectively. ABBV-318 can be used in pain-related research.

     ABBV-318 Chemical Structure
  49. GC62823 Abeprazan Abeprazan (DWP14012) is a potassium-competitive acid blocker. Abeprazan Chemical Structure
  50. GC65377 Abeprazan hydrochloride

    DWP14012 hydrochloride; Fexuprazan hydrochloride

     Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride Chemical Structure
  51. GC35222 ABT-239 ABT-239 is a novel, highly efficacious, non-imidazole?class of H3R antagonist and a transient receptor potential vanilloid type 1 (TRPV1) antagonist. ABT-239 Chemical Structure
  52. GC60549 ABT-418 hydrochloride ABT-418 hydrochloride is a potent and selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. ABT-418 hydrochloride Chemical Structure
  53. GC19016 ABT-639 ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 Chemical Structure
  54. GC33720 ABT-639 hydrochloride ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 hydrochloride Chemical Structure
  55. GC40860 AC1903 AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM). AC1903 Chemical Structure
  56. GN10812 Acacetin

    LY064233, NSC 76061

     Acacetin Chemical Structure
  57. GC11286 ACBC ACBC is a NMDA receptor partial agonist acting at the glycine site, NR1. ACBC Chemical Structure
  58. GC14712 ACET

    UBP316

     ACET (ACET) is a highly potent and selective kainate receptor GluK1 (GluR5) antagonist, with a Kb value of 1.4 nM. ACET Chemical Structure
  59. GC18262 Acetamiprid A neonicotinoid insecticide Acetamiprid Chemical Structure
  60. GC14142 Acetylcholine Chloride

    ACh

     Major transmitter at many nervous sites Acetylcholine Chloride Chemical Structure
  61. GC68602 Acetylcholine-d13 bromide

    ACh-d13 (bromide)

    Acetylcholine-d13 (bromide) is the deuterated form of Acetylcholine bromide.

     Acetylcholine-d13 bromide Chemical Structure
  62. GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. Acetyldigitoxin Chemical Structure
  63. GC30927 Acevaltrate Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively. Acevaltrate Chemical Structure
  64. GC31100 ACT-709478

    ACT-709478

     ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 Chemical Structure
  65. GC46806 Adenosine 5'-diphosphate (potassium salt hydrate)

    5'-ADP, ADP

     A neuropeptide with diverse biological activities Adenosine 5'-diphosphate (potassium salt hydrate) Chemical Structure
  66. GC19729 Adenosine 5′-diphosphoribose sodium

    ADP ribose sodium

     Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5′-diphosphoribose sodium Chemical Structure
  67. GC46083 Adenylosuccinic Acid

    Aspartyl Adenylate

    Adenylosuccinic acid is a purine nucleotide and an intermediate in the purine nucleotide cycle.

     Adenylosuccinic Acid Chemical Structure
  68. GC49231 Adenylosuccinic Acid (ammonium salt) A purine nucleotide and an intermediate in the purine nucleotide cycle Adenylosuccinic Acid (ammonium salt) Chemical Structure
  69. GC13542 Adiphenine HCl

    NSC 129224, Spasmolytin, Trasentin

     Adiphenine HCl is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), with an IC50s of 1.9, 1.8, 3.7, and 6.3 μM for α1, α3β4, α4β2, and α4β4, respectively. Adiphenine HCl Chemical Structure
  70. GC19021 Adjudin

    AF-2364

     Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin Chemical Structure
  71. GC11315 ADWX 1 Kv1.3 channel blocker,potent and selective ADWX 1 Chemical Structure
  72. GC32672 AE0047 Hydrochloride AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease. AE0047 Hydrochloride Chemical Structure
  73. GC19022 AF-353

    Ro-4

     AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0). AF-353 Chemical Structure
  74. GC30844 Afloqualone

    HQ-495

     An Analytical Reference Standard Afloqualone Chemical Structure
  75. GC39248 Afoxolaner An isoxazoline insecticide and acaricide Afoxolaner Chemical Structure
  76. GC14867 Agitoxin 2 Shaker K+ channel blocker, potent Agitoxin 2 Chemical Structure
  77. GC35273 Ajmaline

    NSC 15627

     Ajmaline Chemical Structure
  78. GC45378 Alaproclate (hydrochloride)

    GEA 654, A03

       Alaproclate (hydrochloride) Chemical Structure
  79. GC30371 Alisol F Alisol F is a triterpene isolated from Alisma orientalis, has immunosuppressive and anti-virus functions. Alisol F Chemical Structure
  80. GC40476 Allethrin

    NSC 11782, RU 27436

     Allethrin is a pyrethroid insecticide and modulator of voltage-gated sodium channels (NaV). Allethrin Chemical Structure
  81. GC35293 Allocryptopine

    α-Allocryptopine, α-Fagarine, β-Homochelidonine

     Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb. Allocryptopine Chemical Structure
  82. GC46831 Alloisolithocholic Acid

    AILCA, Isoallolithocholic Acid, NSC 18169

     Alloisolithocholic Acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid, is a T cell regulator. Alloisolithocholic Acid Chemical Structure
  83. GC14192 Allopregnanolone

    ALLO, 3α,5α-tetrahydro Progesterone, 3α,5α-THP; brexanolone

     Allopregnanolone, a 3alpha, 5alpha progesterone metabolite, acts as a potent allosteric modulator of the γ-aminobutyric acid type A (GABAA) receptor, exerts antidepressant and neuroprotective action. Allopregnanolone Chemical Structure
  84. GC30891 Almitrine mesylate (Almitrine bismesylate) Almitrine mesylate (Almitrine bismesylate), a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel. Almitrine mesylate (Almitrine bismesylate) Chemical Structure
  85. GC32673 Almokalant (H 234/09) Almokalant (H 234/09) is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. Almokalant (H 234/09) Chemical Structure
  86. GC30983 alpha-Asarone (α-Asarone)

    transAsarone

     alpha-Asarone (α-Asarone) (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice. alpha-Asarone (α-Asarone) Chemical Structure
  87. GC13515 Alphaxalone activates and potentiates GABAA receptor-activated membrane current (IGABA) Alphaxalone Chemical Structure
  88. GC15467 ALX 5407 hydrochloride GlyT1 inhibitor,selective non-transportable ALX 5407 hydrochloride Chemical Structure
  89. GC70319 ALX-1393 TFA ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model. ALX-1393 TFA Chemical Structure
  90. GC12972 AM 1172 Inhibitor of anandamide uptake and FAAH,potent and selective AM 1172 Chemical Structure
  91. GC50475 AM 12

    TRPC5 inhibitor

     AM 12 Chemical Structure
  92. GC12071 AM 404

    4HPA, N(4hydroxyphenyl)Arachidonoyl Amide

     Anandamide transport inhibitor AM 404 Chemical Structure
  93. GC10943 AM 92016 hydrochloride Potassium channel blocker AM 92016 hydrochloride Chemical Structure
  94. GC19025 AM-0902 AM-0902 is a potent, selective transient receptor potential A1 (TRPA1) antagonist with IC50s of 71 and 131 nM for rTRPA1 and hTRPA1, respectively. AM-0902 Chemical Structure
  95. GC30917 AM-2099 AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7. AM-2099 Chemical Structure
  96. GC15458 Ambroxol HCl

    NA 872

     Ambroxol HCl (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol HCl Chemical Structure
  97. GC50058 AMG 21629 Potent and selective TRPV1 antagonist AMG 21629 Chemical Structure
  98. GC65611 AMG 333 AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM. AMG 333 Chemical Structure
  99. GC11926 AMG 9810 TRPV1 antagonist AMG 9810 Chemical Structure
  100. GC13003 AMG-517 TRPV1 antagonist,potent and highly selective AMG-517 Chemical Structure
  101. GC35316 AMG2850 AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist. AMG2850 Chemical Structure

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