Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC35567 Bullatine A Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects.
- GC35568 Bulleyaconitine A Bulleyaconitine A is an analgesic and antiinflammatory drug isolated from Aconitum plants; has several potential targets, including voltage-gated Na+ channels.
- GC15524 Bumetanide NKCC cotransporter inhibitor
- GC46957 Bumetanide-d5 An internal standard for the quantification of bumetanide
- GC42990 Bupivacaine Bupivacaine is a sodium channel blocker and local anesthetic.
- GC12410 Bupivacaine HCl Bupivacaine HCl is a NMDA receptor inhibitor.
- GC30914 Butamben (Butyl 4-aminobenzoate) Butamben (Butyl 4-aminobenzoate) (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions.
- GC50200 BX 430 Selective P2X4 allosteric antagonist
- GC64574 BZAD-01 BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM.
- GC15898 BzATP triethylammonium salt P2X7 receptor agonist
- GC30977 Ca2+ channel agonist 1 Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.
- GC14768 CaCCinh-A01 calcium-activated chloride channel (CaCC) inhibitor
- GN10792 Caffeic acid
-
GC43115
Cal Green™ 1 (potassium salt)
Cal Green™ 1 is a cell-impermeant fluorescent calcium indicator that is characterized by high quantum yield and low phototoxicity.
- GC43116 Cal Green™ 1 AM Cal Green™ 1 AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm).
- GC32616 Calcium channel-modulator-1 Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.
-
GC10949
Calcium Ionophore I
Ca2+-selective ionophore
- GC34041 Caldaret (MCC-135) Caldaret (MCC-135) is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.
-
GC14326
Calmidazolium chloride
Calmodulin antagonist
- GC62885 Caloxin 2A1 TFA Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor.
-
GC12104
CALP1
Cell-permeable calmodulin (CaM) agonist
- GC65081 CALP1 TFA CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 ?M) with binding to the CaM EF-hand/Ca2+-binding site.
- GC14889 CALP2 Cell-permeable calmodulin (CaM) antagonist
- GC61508 CALP2 TFA CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 ?M) with high affinity for binding to the CaM EF-hand/Ca2+-binding site.
- GC17687 CALP3 Cell-permeable calmodulin (CaM) agonist
- GC31953 Camphor ((±)-Camphor) Camphor ((±)-Camphor) ((±)-Camphor ((±)-Camphor)) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative.
- GC15930 Camstatin analog of PEP-19 with antagonism of calmodulin
- GC14065 Capsaicin A terpene alkaloid with diverse biological activities
- GC17918 Capsazepine A TRPV1 antagonist
- GC49433 Capsiate A capsaicin analog with diverse biological activities
- GC12636 Capsiconiate TRPV1 agonist
- GC17340 Carbamazepine Inhibitor of neuronal voltage-gated Na+ channels
-
GC16937
Carbamoylcholine chloride
Cholinergic receptor agonist
- GC39646 Carboxyamidotriazole Orotate Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor.
- GC31224 Carburazepam (RGH 3331) Carburazepam (RGH 3331) is a drug which derives from benzodiazepine.
- GC18069 Cardamonin Cardamonin ((E)-Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.
- GC17842 CARIPORIDE Potent NHE inhibitor
- GC18505 Carisbamate Carisbamate (RWJ-333369) is an orally active neuromodulator.
- GC61963 Caroverine hydrochloride Caroverine (Tinnex) hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor.
- GN10791 Catharanthine
- GN10715 Catharanthine Tartrate
- GC35619 Cav 2.2 blocker 1 Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM.
- GC65959 CaV1.3 antagonist-1 CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research.
- GC63976 Cavosonstat Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor.
- GC43152 CAY10412 Anandamide (arachidonoyl ethanolamide; AEA) is an endogenous lipid with cannabinergic activity; along with 2-arachidonoyl glycerol, it forms part of the endocannabinoid system.
- GC43155 CAY10448 Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper.
- GC43182 CAY10608 N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine.
- GC43199 CAY10719 CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1.
- GC50557 CBA CBA (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM.
- GC50126 CC4 High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist
- GC12119 CCMI Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR)
- GC12137 CCMQ inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites
- GC31332 CDN1163 An allosteric activator of SERCA2
- GC31157 CE-224535 (PF-04905428) CE-224535 (PF-04905428) is a selective P2X7 receptor antagonist.
- GC49706 Cerberin A cardiac glycoside with cytotoxic and cardiac modulatory activities
- GC18079 CFM-2 AMPA antagonist
- GC35667 CFTR corrector 1 CFTR corrector 1 (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR).
- GC34532 CFTR corrector 2 CFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR), extracted from patent US20140274933.
- GC67939 CFTR corrector 4
- GC62510 CFTR corrector 6 CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR).
- GC68282 CFTR corrector 8
- GC65029 CFTR corrector 9 CFTR corrector 9 (compound 42) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator.
- GC14421 CFTRinh-172 CFTR inhibitor, highly potent and selective
- GC13374 CGP 13501 Positive modulator of GABAB receptors,allosteric
- GC11153 CGP 35348 Selective GABAB antagonist, brain penetrant
- GC13676 CGP 36216 hydrochloride Selective GABAB antagonist
- GC35669 CGP 36742 CGP 36742 is a selective GABAB receptor antagonist that can penetrate the blood–brain barrier after peripheral administration, with an IC50 of 32?μM.
-
GC11630
CGP 37157
Antagonist of mitochondrial Na+-Ca2+ exchanger
- GC38493 CGP 37849
- GC10122 CGP 37849 NMDA receptor antagonist
- GC11027 CGP 39551 NMDA antagonist
- GC13131 CGP 46381 GABAB receptor antagonist
- GC16947 CGP 52432 GABAB receptor antagonist
-
GC10489
CGP 54626 hydrochloride
GABAB receptor antagonist
- GC16600 CGP 55845 hydrochloride GABAB receptor antagonist
- GC15752 CGP 78608 hydrochloride NMDA antagonist
- GC15563 CGP 7930 Positive allosteric modulator of GABAB receptors
- GC33751 CGP11952 CGP11952 is a triazolyl-Benzaphenon resembling the benzodiazepines in its pharmacological action.
- GC16272 CGS 19755 NMDA receptor antagonist
- GC14274 CGS 20625 partial agonist for the benzodiazepine binding site of the GABAA receptor
- GC16911 CGS 9343B CGS 9343B (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin.
- GC17272 Charybdotoxin inhibitor of the big conductance Ca2+-activated K+ channel
- GC61534 Charybdotoxin TFA Charybdotoxin TFA, a 37-amino acid peptide, is a K+ channel blocker.
- GC10877 CHC CHC (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs).
- GC32250 Chebulinic acid An ellagitannin with diverse biological activities
- GC16311 Chlormethiazole hydrochloride GABAA agonist
- GC16691 Chlormezanone Anxiolytic and skeletal muscle relaxant
- GC33024 Chlorotoxin Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.
- GC38498 Chlorotoxin (TFA)
- GC30280 Chlorpromazine D6 hydrochloride An internal standard for the quantification of chlorpromazine
-
GC14216
Chlorpromazine HCl
dopamine receptor antagonist
- GC17086 Chlorpropamide Oral antihyperglycemic agent
- GC49191 Chlorzoxazone-d3 An internal standard for the quantification of chlorzoxazone
- GC46118 Chlothianidin A neonicotinoid insecticide
- GC43261 Cholesteryl Myristate Cholesteryl Myristate is a natural steroid present in traditional Chinese medicine. Cholesteryl Myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.
- GC10213 Chromanol 293B slow delayed rectifier K+ current (IKs) blocker
- GC35692 Chrysosplenetin A flavonoid with diverse biological activities
- GC14477 CI 966 hydrochloride GABA transporter GAT-1 inhibitor
- GC64925 Cibenzoline Cibenzoline is a potent inhibitor of KATP channel with directly affecting the pore-forming Kir6.2 subunit rather than the SUR1 subunit.
- GC11120 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech.