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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> ATPase

ATPase

ATPase is a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion, including some co-transporters and pumps.

Products for  ATPase

  1. Cat.No. Product Name Information
  2. GC40434 (±)16-HETE

    (±)16-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE Chemical Structure
  3. GC13430 (-)-Blebbistatin

    (S)Blebbistatin

     (-)-Blebbistatin is one of the configurations of the racemic mixture (±)-Blebbistatin (Cat. No. GC12341) and is the active form. (-)-Blebbistatin is a cell-permeable inhibitor of non-muscle myosin II ATPase, which effectively inhibits multiple striated muscle myosins as well as vertebrate non-muscle myosins with IC50 values ranging from 0.5-5μM, and only slightly inhibits smooth muscle myosin (IC50=80μM) . (-)-Blebbistatin Chemical Structure
  4. GC41719 (R)-nitro-Blebbistatin

    R(-)7Desmethyl8nitro Blebbistatin

     (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin Chemical Structure
  5. GC41557 (S)-3'-amino Blebbistatin

    (-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin

     (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin Chemical Structure
  6. GC41484 (S)-3'-hydroxy Blebbistatin

    (-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin

     (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin Chemical Structure
  7. GC41091 (S)-Lansoprazole

    (-)-Lansoprazole

     (S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 μM), inhibiting gastric acid secretion and increasing intragastric pH. (S)-Lansoprazole Chemical Structure
  8. GC41739 (S)-nitro-Blebbistatin

    S(-)7Desmethyl8nitro Blebbistatin

     (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin Chemical Structure
  9. GC46047 14-Anhydrodigitoxigenin A cardenolide 14-Anhydrodigitoxigenin Chemical Structure
  10. GC40453 16(R)-HETE

    16(R)-Hydroxyeicosatetraenoic Acid

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.

     16(R)-HETE Chemical Structure
  11. GC40454 16(S)-HETE

    16(S)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16(S)-HETE Chemical Structure
  12. GC40455 17(R)-HETE

    17(R)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17(R)-HETE Chemical Structure
  13. GC40456 17(S)-HETE

    17(S)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17(S)-HETE Chemical Structure
  14. GC12469 2,3-Butanedione-2-monoxime

    BDM|Diacetyl Monoxime|NSC 660|NSC 116103

     2,3-Butanedione-2-monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor. 2,3-Butanedione-2-monoxime Chemical Structure
  15. GC49575 4-hydroxy Omeprazole sulfide

    4-hydroxy OMEP sulfide, 4-hydroxy OMP sulfide, 4-hydroxy OMZ sulfide

     A metabolite of omeprazole 4-hydroxy Omeprazole sulfide Chemical Structure
  16. GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. Acetyldigitoxin Chemical Structure
  17. GC46841 Amiloride (hydrochloride) (hydrate)

    MK-870

     A neuropeptide with diverse biological activities Amiloride (hydrochloride) (hydrate) Chemical Structure
  18. GC42827 Apoptolidin

    Apoptolidin A

     Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. Apoptolidin Chemical Structure
  19. GC17225 ARL 67156 trisodium salt

    FPL 67156 trisodium

     ARL67156 (FPL 67156) trisodium is a selective ecto-ATPase inhibitor. ARL 67156 trisodium salt Chemical Structure
  20. GC35421 ATP synthase inhibitor 1 ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels. ATP synthase inhibitor 1 Chemical Structure
  21. GC10934 Bafilomycin C1

    2-Demethyl-2-methoxy-24-methyl-hygrolidin,L-681,110A1

     vacuolar H+-ATPases (V-ATPases) inhibitor Bafilomycin C1 Chemical Structure
  22. GC12302 Bafilomycin D vacuolar H+ ATPases (V-ATPases) inhibitor Bafilomycin D Chemical Structure
  23. GC14664 BHQ BHQ (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) . BHQ Chemical Structure
  24. GC42965 Bongkrekic Acid

    Bongkrek Acid

    An inhibitor of mitochondrial adenine nucleotide translocase

     Bongkrekic Acid Chemical Structure
  25. GC17683 Brefeldin A

    Ascotoxin, BFA, Cyanein, Decumbin, Nectrolide, NSC 56310, NSC 89671, NSC 107456, NSC 244390, Synergisidin

     Brefeldin A (BFA) is a fungal macrocyclic lactone and a potent, reversible inhibitor of intracellular vesicle formation and protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus. Brefeldin A Chemical Structure
  26. GC16833 BTB06584

    BTB

     F1F0 ATP synthases BTB06584 Chemical Structure
  27. GC47021 Caloxin 2A1 (trifluoroacetate salt)

    VSNSNWPSFPSSGGG-NH2

     A neuropeptide with diverse biological activities Caloxin 2A1 (trifluoroacetate salt) Chemical Structure
  28. GC49706 Cerberin

    2′-Acetylneriifolin

     A cardiac glycoside with cytotoxic and cardiac modulatory activities Cerberin Chemical Structure
  29. GC11120 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox ethanolamine Chemical Structure
  30. GC10268 Cyclopiazonic acid

    NSC 117181

    sarcoplasmic reticulum Ca2+-ATPase inhibitor

     Cyclopiazonic acid Chemical Structure
  31. GC47149 Cyclopiazonic Acid-13C20

    CPA-13C20

     A neuropeptide with diverse biological activities Cyclopiazonic Acid-13C20 Chemical Structure
  32. GC18583 D-α-Hydroxyglutaric Acid

    D-2-HG, D-2-Hydroxyglutaric Acid

     Over-produced in the human neurometabolic disease D-2-HGA D-α-Hydroxyglutaric Acid Chemical Structure
  33. GC43412 Desacetyl Bisacodyl

    DAB, DDPM

     Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate. Desacetyl Bisacodyl Chemical Structure
  34. GC13108 Digoxin

    NSC 95100

     Digoxin is a potent Na+/K+-ATPase inhibitor clinically used to treat arrhythmias and heart failure. Digoxin Chemical Structure
  35. GC43565 Doxorubicinol (hydrochloride)

    13-Dihydroadriamycin hydrochloride

     Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Doxorubicinol (hydrochloride) Chemical Structure
  36. GC10395 Dynasore Dynasore, as a GTPase inhibitor, can rapidly and reversibly inhibit dynamin activity, which prevents endocytosis. Dynasore Chemical Structure
  37. GC18105 Enterostatin Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake. Enterostatin Chemical Structure
  38. GC48984 Esomeprazole

    (-)-Omeprazole, (S)-Omeprazole

     An H+/K+-ATPase inhibitor Esomeprazole Chemical Structure
  39. GC33234 Gboxin

    Gboxin is an inhibitor of oxidative phosphorylation (OXPHOS) in cancer cells and can be targeted to inhibit glioblastoma (GBM).

     Gboxin Chemical Structure
  40. GC16585 Golgicide A

    GCA

    GBF1 inhibitor, potent, reversible and highly specific

     Golgicide A Chemical Structure
  41. GC71972 Isofalcarintriol Isofalcarintriol is a NRF2 activator and selective inhibitor of the mitochondrial ATP synthase. Isofalcarintriol Chemical Structure
  42. GC11448 Istaroxime

    PST-2744;PST 2744;PST2744

     Istaroxime Chemical Structure
  43. GC17786 Istaroxime hydrochloride Istaroxime hydrochloride Chemical Structure
  44. GC16167 K 858 K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC50 of 1.3 μM. K 858 Chemical Structure
  45. GC47532 KUS121 A VCP modulator KUS121 Chemical Structure
  46. GC49640 Lansoprazole N-oxide A potential impurity found in bulk preparations of lansoprazole Lansoprazole N-oxide Chemical Structure
  47. GC11254 Lithium carbonate Na+/K+ ATPase pump inhibitor Lithium carbonate Chemical Structure
  48. GC14059 ML 240 ATP-competitive inhibitor of p97 ATPase ML 240 Chemical Structure
  49. GC11411 ML-7 hydrochloride A smooth muscle myosin light chain kinase inhibitor ML-7 hydrochloride Chemical Structure
  50. GC15858 MYK-461

    MYK-461, SAR439152

     MYK-461 (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. MYK-461 Chemical Structure
  51. GC11587 Ochratoxin A

    NSC 201422, NSC 221991, OTA

    endoplasmic reticulum ATP-dependent calcium pump activator

     Ochratoxin A Chemical Structure
  52. GC16859 Oligomycin A

    MCH 32

     Oligomycin A is an inhibitor of ATP synthase, which inhibits the process taking place on mitochondria coupling membrane that depended on ATP and oxidative phosphorylation. Oligomycin A Chemical Structure
  53. GC16409 Oligomycin B mitochondrial F1FO ATP synthase inhibitor Oligomycin B Chemical Structure
  54. GC16221 Oligomycin C

    12-deoxy Oligomycin A

     mitochondrial F1FO-ATP synthase inhibitor Oligomycin C Chemical Structure
  55. GC16533 Oligomycin Complex

    Oligomycin complex consists of a blend of oligomycins A, B, and C.

     Oligomycin Complex Chemical Structure
  56. GC12832 Omecamtiv mecarbil

    CK-1827452; CK1827452

     Cardiac myosin activator Omecamtiv mecarbil Chemical Structure
  57. GC47826 Omeprazole sulfone-d3

    OMEP sulfone-d3, OMP sulfone-d3, OMZ sulfone-d3

     A neuropeptide with diverse biological activities Omeprazole sulfone-d3 Chemical Structure
  58. GC49663 Pantoprazole sulfone N-oxide A potential impurity found in bulk preparations of pantoprazole Pantoprazole sulfone N-oxide Chemical Structure
  59. GC45539 Pantoprazole-d6

    BY1023-d6; SKF96022-d6

       Pantoprazole-d6 Chemical Structure
  60. GC12788 Paprotrain

    Passenger Proteins Transport Inhibitor

    mitotic kinesin-like protein 2 (MKLP-2) inhibitor

     Paprotrain Chemical Structure
  61. GC45944 para-amino-Blebbistatin

    (-)-4'-amino-Blebbistatin, p-amino-Blebbistatin, (S)-4'-amino-Blebbistatin

     A more stable and less phototoxic form of (–)-blebbistatin with enhanced water solubility para-amino-Blebbistatin Chemical Structure
  62. GC11082 Paxilline Paxilline is a tremor-causing fungal alkaloid that can effectively inhibit high-conductance Ca2+-activated K+ (BK) channels, with IC50 of approximately 10nM and Ki=1.9nM. Paxilline Chemical Structure
  63. GC17027 POM 1

    Sodium Metatungstate, Sodium Polyoxotungstate

     POM 1 is a nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor with Ki values of 2.58μM, 3.26μM and 28.8μM for NTPDase1 (CD39), NTPDase3 and NTPDase2, respectively. POM 1 Chemical Structure
  64. GC10371 PSB 06126 NTPDase 3 inhibitor PSB 06126 Chemical Structure
  65. GC13186 PSB 069 NTPDase inhibitor PSB 069 Chemical Structure
  66. GC49627 Rabeprazole sulfone A metabolite of rabeprazole Rabeprazole sulfone Chemical Structure
  67. GC10906 RBC8 Ral GTPase inhibitor RBC8 Chemical Structure
  68. GC11151 SCH 28080 H+,K+-ATPase inhibitor SCH 28080 Chemical Structure
  69. GC14368 Sodium Orthovanadate

    NSC 79534

     PTP inhibitor Sodium Orthovanadate Chemical Structure
  70. GC60348 Supinoxin

    RX-5902

     Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent. Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of β-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC50s ranging from 10 nM to 20 nM. Supinoxin Chemical Structure
  71. GC15418 TAK-438

    TAK-438

     Blocker of potassium-competitive acid TAK-438 Chemical Structure
  72. GC18005 Tenatoprazole

    TU-199

     proton pump inhibitor Tenatoprazole Chemical Structure
  73. GC25991 tetrathiomolybdate Tetrathiomolybdate (TM) is used in the clinic for the treatment of Wilson's disease by inducing dimerization of the metal-binding domain of the cellular copper efflux protein ATP7B (WLN4) through a unique sulfur-bridged Mo2S6O2 cluster. tetrathiomolybdate Chemical Structure
  74. GC11482 Thapsigargin Thapsigargin is an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase pump. Thapsigargin Chemical Structure
  75. GC49503 Thujopsene

    NSC 44707, cis-(-)-Thujopsene

     A sesquiterpene with diverse biological activities Thujopsene Chemical Structure
  76. GC72771 Triciribine phosphate sodium

    TCN-P sodium

     Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium Chemical Structure
  77. GC61374 Vonoprazan Fumarate

    TAK-438

     A selective and reversible proton pump inhibitor Vonoprazan Fumarate Chemical Structure
  78. GC49430 Wee1 Inhibitor Wee1 Inhibitor is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM. Wee1 Inhibitor Chemical Structure

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