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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Calcium Channel

Calcium channel is an ion channel that selectively permeable to calcium ions. It serves vital functions in cellular signal transduction.

Products for  Calcium Channel

  1. Cat.No. Product Name Information
  2. GC15513 ω-Agatoxin IVA ω-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA Chemical Structure
  3. GC12608 ω-Agatoxin TK ω-Agatoxin TK, a peptidyl toxin of the venom of Agelenopsis aperta, is a potent and selective P/Q type Ca2+ channel blocker. ω-Agatoxin TK Chemical Structure
  4. GC13886 ω-Conotoxin GVIA ω-Conotoxin GVIA is a cone snail toxin that selectively blocks N-type channels in neurons . ω-Conotoxin GVIA Chemical Structure
  5. GC18070 ω-Conotoxin MVIIC wide spectrum blocker of N, P and Q type calcium channels ω-Conotoxin MVIIC Chemical Structure
  6. GC31248 β-Amino Acid Imagabalin Hydrochloride (PD-0332334) β-Amino Acid Imagabalin Hydrochloride (PD-0332334) (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel. β-Amino Acid Imagabalin Hydrochloride (PD-0332334) Chemical Structure
  7. GC70188 ω-Agatoxin IVA TFA

    ω-Agatoxin IVA TFA is an effective selective blocker of P/Q-type Ca2+ (Cav2.1) channels, with IC50 values of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA TFA (IC50, 30-225 nM) inhibits high potassium-induced glutamate release and calcium influx. It also blocks the release of serotonin and adrenaline induced by high potassium, without affecting L-type or N-type calcium channels.

     ω-Agatoxin IVA TFA Chemical Structure
  8. GA24016 ω-Conotoxin MVIIA ω-Conotoxin MVIIA (SNX-111), a peptide, is a potent and selective block of N-type calcium channels antagonist. ω-Conotoxin MVIIA Chemical Structure
  9. GC64899 ω-Conotoxin MVIIC TFA ω-Conotoxin MVIIC TFA Chemical Structure
  10. GN10612 (+)- Praeruptorin C (+)- Praeruptorin C Chemical Structure
  11. GC30933 (+)-Kavain

    An Analytical Reference Standard

     (+)-Kavain Chemical Structure
  12. GC63940 (-)-Denudatin B (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B Chemical Structure
  13. GN10445 (-)-pareruptorin A (-)-pareruptorin A Chemical Structure
  14. GC14484 (-)-Xestospongin C

    IP3-dependent Ca2+ release inhibitor

     (-)-Xestospongin C Chemical Structure
  15. GC50536 (2R/S)-6-PNG CaV3.2 blocker; active in vivo (2R/S)-6-PNG Chemical Structure
  16. GC13895 (R)-(+)-Bay K 8644 L-type Ca2+-channel blocker (R)-(+)-Bay K 8644 Chemical Structure
  17. GC66419 (R)-Lercanidipine-d3 hydrochloride (R)-lercanidipine D3 (hydrochloride) is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride), the R-enantiomer of Lercanidipine, is a calcium channel blocker. (R)-Lercanidipine-d3 hydrochloride Chemical Structure
  18. GC68475 (R)-Nicardipine (R)-Nicardipine Chemical Structure
  19. GC61873 (Rac)-MEM 1003 (Rac)-MEM 1003 is the racemate of MEM 1003. (Rac)-MEM 1003 Chemical Structure
  20. GC14229 (S)-(-)-Bay K 8644 L-type Ca2+-channel activator (S)-(-)-Bay K 8644 Chemical Structure
  21. GC63321 (S)-(-)-Felodipine-d5 (S)-(-)-Felodipine-d5 Chemical Structure
  22. GC60418 (S)-Lercanidipine hydrochloride (S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-Lercanidipine hydrochloride Chemical Structure
  23. GC68476 (S)-Nicardipine (S)-Nicardipine Chemical Structure
  24. GC60425 (S)-Verapamil D7 hydrochloride (S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil D7 hydrochloride Chemical Structure
  25. GC60008 (S)-Verapamil hydrochloride (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil hydrochloride Chemical Structure
  26. GC18603 (±)-Methoxyverapamil (hydrochloride) (±)-Methoxyverapamil (hydrochloride) (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. (±)-Methoxyverapamil (hydrochloride) Chemical Structure
  27. GC61898 1,2,4-Trihydroxybenzene 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. 1,2,4-Trihydroxybenzene Chemical Structure
  28. GC45980 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol A triacylglycerol 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol Chemical Structure
  29. GC39470 1-Octanol 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol Chemical Structure
  30. GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine A metabolite of carbamazepine and oxcarbazepine 10,11-dihydro-10,11-dihydroxy Carbamazepine Chemical Structure
  31. GC17562 2-APB

    2-APB is an antagonist of the Ins(1,4,5)P3 receptor, with an IC50 value of 42μM when the concentration of InsP3 is 100 nm. 2-APB is also an inhibitor of TRPV6 and a modulator of various TRP channels.

     2-APB Chemical Structure
  32. GC42475 4α-Phorbol 12,13-didecanoate 4α-Phorbol 12,13-didecanoate is a negative control for phorbol esters, phorbol 12-myristate 13-acetate and phorbol 12,13-didecanoate (PDD). 4α-Phorbol 12,13-didecanoate Chemical Structure
  33. GC42346 4-bromo A23187

    4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187.

     4-bromo A23187 Chemical Structure
  34. GC10119 8-Bromo-cGMP, sodium salt 8-Bromo-cGMP, sodium salt, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator. 8-Bromo-cGMP, sodium salt Chemical Structure
  35. GC42621 8-bromo-Cyclic ADP-Ribose (sodium salt) Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. 8-bromo-Cyclic ADP-Ribose (sodium salt) Chemical Structure
  36. GC11178 A-7 hydrochloride calmodulin antagonist A-7 hydrochloride Chemical Structure
  37. GC11200 A23187

    A23187, free acid is a Ca2+ ionophore

     A23187 Chemical Structure
  38. GC19016 ABT-639 ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 Chemical Structure
  39. GC33720 ABT-639 hydrochloride ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 hydrochloride Chemical Structure
  40. GC14142 Acetylcholine Chloride Major transmitter at many nervous sites Acetylcholine Chloride Chemical Structure
  41. GC31100 ACT-709478 ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 Chemical Structure
  42. GC32672 AE0047 Hydrochloride AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease. AE0047 Hydrochloride Chemical Structure
  43. GC18274 Amiprofos-methyl Amiprofos-methyl (APM) is a phosphoric amide herbicide. Amiprofos-methyl Chemical Structure
  44. GC13523 Amlodipine Calcium channel blocker Amlodipine Chemical Structure
  45. GC13146 Amlodipine Besylate Block of L-type calcium channel Amlodipine Besylate Chemical Structure
  46. GC35325 Amlodipine maleate Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate Chemical Structure
  47. GC32566 Anipamil Anipamil is a long-acting calcium channel blocker, used for the treatment of cardiovascular disease. Anipamil Chemical Structure
  48. GC34049 Aranidipine (MPC1304) Aranidipine (MPC1304) (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. Aranidipine (MPC1304) Chemical Structure
  49. GC15099 Autocamtide-2-related inhibitory peptide inhibitor of calmodulin-dependent protein kinase II (CaM-kinase II, CaMKII) Autocamtide-2-related inhibitory peptide Chemical Structure
  50. GC15101 Azelnidipine L-type calcium channel blocker;antihypertensive Azelnidipine Chemical Structure
  51. GC35451 Azelnidipine D7 Azelnidipine D7 Chemical Structure
  52. GC61493 Azumolene Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene Chemical Structure
  53. GC42893 Azumolene (sodium salt) Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. Azumolene (sodium salt) Chemical Structure
  54. GC35469 Barnidipine Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. Barnidipine Chemical Structure
  55. GC13289 Barnidipine (hydrochloride) calcium-channel blocker Barnidipine (hydrochloride) Chemical Structure
  56. GC13888 Benidipine HCl Benidipine HCl is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). Benidipine HCl Chemical Structure
  57. GC15533 Bepridil hydrochloride Calcium channel blocker Bepridil hydrochloride Chemical Structure
  58. GC39743 Bepridil hydrochloride hydrate Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate Chemical Structure
  59. GC39546 Bevantolol hydrochloride A β1-AR antagonist Bevantolol hydrochloride Chemical Structure
  60. GC42984 BTC (potassium salt) BTC (potassium salt) is a low affinity calcium indicator (Kd approximately 7-26 μM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg2+, and accuracy of ratiometric measurement. BTC (potassium salt) Chemical Structure
  61. GC42985 BTC AM BTC AM is a cell-permeable acetoxy-methyl ester of BTC. BTC AM Chemical Structure
  62. GC50200 BX 430 Selective P2X4 allosteric antagonist BX 430 Chemical Structure
  63. GC30977 Ca2+ channel agonist 1 Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. Ca2+ channel agonist 1 Chemical Structure
  64. GC43115 Cal Green™ 1 (potassium salt)

    Cal Green™ 1 is a cell-impermeant fluorescent calcium indicator that is characterized by high quantum yield and low phototoxicity.

     Cal Green™ 1 (potassium salt) Chemical Structure
  65. GC43116 Cal Green™ 1 AM Cal Green™ 1 AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Cal Green™ 1 AM Chemical Structure
  66. GC32616 Calcium channel-modulator-1 Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 Chemical Structure
  67. GC14326 Calmidazolium chloride

    Calmodulin antagonist

     Calmidazolium chloride Chemical Structure
  68. GC12104 CALP1

    Cell-permeable calmodulin (CaM) agonist

     CALP1 Chemical Structure
  69. GC65081 CALP1 TFA CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 ?M) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 TFA Chemical Structure
  70. GC14889 CALP2 Cell-permeable calmodulin (CaM) antagonist CALP2 Chemical Structure
  71. GC61508 CALP2 TFA CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 ?M) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA Chemical Structure
  72. GC17687 CALP3 Cell-permeable calmodulin (CaM) agonist CALP3 Chemical Structure
  73. GC15930 Camstatin analog of PEP-19 with antagonism of calmodulin Camstatin Chemical Structure
  74. GC39646 Carboxyamidotriazole Orotate Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate Chemical Structure
  75. GN10791 Catharanthine Catharanthine Chemical Structure
  76. GN10715 Catharanthine Tartrate Catharanthine Tartrate Chemical Structure
  77. GC35619 Cav 2.2 blocker 1 Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM. Cav 2.2 blocker 1 Chemical Structure
  78. GC65959 CaV1.3 antagonist-1 CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research. CaV1.3 antagonist-1 Chemical Structure
  79. GC31332 CDN1163 An allosteric activator of SERCA2 CDN1163 Chemical Structure
  80. GC16911 CGS 9343B CGS 9343B (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. CGS 9343B Chemical Structure
  81. GC12312 Cilnidipine Blocker of Dual L- and N-type calcium channel Cilnidipine Chemical Structure
  82. GC11695 Cinnarizine antihistamine and calcium channel blocker Cinnarizine Chemical Structure
  83. GC60709 Cinnarizine D8 An internal standard for the quantification of cinnarizine Cinnarizine D8 Chemical Structure
  84. GC12095 cis-Ned 19 nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist cis-Ned 19 Chemical Structure
  85. GC16128 Clevidipine Butyrate Clevidipine Butyrate is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension. Clevidipine Butyrate Chemical Structure
  86. GC35738 CP-060 CP-?060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities. CP-060 Chemical Structure
  87. GC17690 Cromolyn sodium Mast cell membrane stabilizer Cromolyn sodium Chemical Structure
  88. GC31834 CV-159 CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities. CV-159 Chemical Structure
  89. GC63967 Cycleanine Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine Chemical Structure
  90. GC62179 Cyclic ADP-ribose Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose Chemical Structure
  91. GC43338 Cyclic ADP-Ribose (ammonium salt) Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types. Cyclic ADP-Ribose (ammonium salt) Chemical Structure
  92. GC61792 Cyclic ADP-ribose ammonium Cyclic ADP-ribose ammonium Chemical Structure
  93. GC43516 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) Chemical Structure
  94. GC43522 D-myo-Inositol-1,4,5-triphosphate (potassium salt) D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. D-myo-Inositol-1,4,5-triphosphate (potassium salt) Chemical Structure
  95. GC43523 D-myo-Inositol-1,4,5-triphosphate (sodium salt) Primary intracellular IP3 receptor agonist D-myo-Inositol-1,4,5-triphosphate (sodium salt) Chemical Structure
  96. GC30054 Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Chemical Structure
  97. GC15868 Dantrolene, sodium salt Dantrolene, sodium salt is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene, sodium salt Chemical Structure
  98. GC31301 Darodipine (PY 108-068) Darodipine (PY 108-068) (PY 108-068, PY-108068) is a potent calcium channel antagonist. Darodipine (PY 108-068) Chemical Structure
  99. GC11070 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body . Dehydroepiandrosterone (DHEA) Chemical Structure
  100. GC33486 Dehydronitrosonisoldipine

    A calcium channel antagonist

     Dehydronitrosonisoldipine Chemical Structure
  101. GC49866 Desmethyl Carvedilol An active metabolite of carvedilol Desmethyl Carvedilol Chemical Structure

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