GABA Receptor
GABA receptors are a class of receptors that respond to the GABA (neurotransmitter gamma-aminobutyric acid), the chief inhibitory neurotransmitter in the vertebrate central nervous system.
Products for GABA Receptor
- Cat.No. Product Name Information
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GC69495
MRK-898
MRK-898 is an orally effective GABA(A) receptor modulator. MRK-898 binds to the α1, α2, α3 and α5 subunits of the GABA receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM and 0.50 nM respectively. However, GABA(A) receptors containing the α1 subunit have been identified as "sedative" receptors while those containing the α2 and/or α3 subunits have been identified as "anxiolytic" subtypes.
- GC16353 N-ArachidonylGABA arachidonyl amino acid
- GC12169 NCS-382 γ-Hydroxybutyric acid antagonist
- GC11901 Nefiracetam GABA receptor activator
- GC31018 NEO 376 (SPI-376) NEO 376 (SPI-376) is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with anti-psychotic actively.
- GC16564 Niflumic acid Ca2+-activated Cl- channel blocker
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GC11821
NNC 05-2090 hydrochloride
GABA uptake inhibitor
- GC11748 NNC 711 NNC-711 (hydrochloride) is a potent and selective inhibitor of GAT-1 ( GABA transporter 1) with an IC50 of 40 nM for hGAT-1.
- GC11143 NS 11394 GABA(A) receptor-positive modulator
- GC16024 Ocinaplon GABAA receptors modulator
- GC19271 ONO-8590580 ONO-8590580 is a GABAA α5 negative allosteric modulator.
- GC14329 Org 20599 GABAA receptor agonist
- GC11963 Oxiracetam cyclic derivative of gamma-aminobutyric acid (GABA)
- GC31282 p-Hydroxybenzaldehyde p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
- GC12357 Pentylenetetrazole CNS stimulant
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GC17691
Phaclofen
GABAB antagonist
- GC13557 PHP 501 trifluoroacetate GABAA antagonist
- GC30827 Pipequaline (PK-8165) Pipequaline (PK-8165) (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity.
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GC16569
PK 11195
peripheral benzodiazepine antagonist
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GC17399
Pregnanolone
GABAA receptor positive allosteric modulator
- GC15960 Primidone anticonvulsant of the pyrimidinedione class
- GC65057 Propofol-d18 Propofol-d18 is the deuterium labeled Propofol.
- GC16476 rac BHFF GABAB receptor positive allosteric modulator
- GC65513 Radequinil Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist.
- GC31257 Rilmazafone hydrochloride (450191S) Rilmazafone hydrochloride (450191S) (450191S) is a benzodiazepine (omega) ligand.
- GC13802 Riluzole Sodium channel protein inhibitor
- GC44841 Riluzole (hydrochloride) Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM).
- GC16780 Ro 15-4513 benzodiazepine ligand
- GC12377 Ro 19-4603 Benzodiazepine inverse agonist
- GC30433 Ru-32514 Ru-32514 is an agonist of benzodiazepine receptor.
- GC11612 RuBi GABA trimethylphosphine GABAB receptor agonist
- GC17321 RuBi-GABA Ruthenium-bipyridine-triphenylphosphine caged GABA
- GC13792 Rufinamide voltage-gated sodium channel blocker
- GC31049 RWJ-51204 RWJ-51204 is a partial agonist of GABA(A) receptor, with Ki of 0.2-2 nM to the benzodiazepine site on GABA(A) receptors.
- GC17257 Saclofen GABAB receptor antagonist
- GC16356 SB 205384 positive GABAA receptor modulator
- GC10888 SCH 50911 GABAB antagonist
- GC10844 SCS GABAA receptor antagonist
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GC69905
SJM-3
SJM-3 is a positive allosteric modulator of different subtypes of GABAA receptors. SJM-3 binds with high affinity to the α+/γ- subunit interface of the benzodiazepine binding site.
- GC15226 SKF 89976A hydrochloride GABA uptake inhibitor
- GC14942 SKF 97541 GABAB agonist
- GC10101 SR 95531 hydrobromide SR 95531 hydrobromide is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor.
- GC34362 SSD114 hydrochloride SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator.
- GC10967 TACA GABAA agonist
- GC17934 TB 21007 GABAA receptor inverse agonist
- GC15859 TCS 1105 GABAA benzodiazepine receptor (BZR) ligand
- GC10741 TCS 1205 TCS 1205 (compound 2b) is a potent and selective GABAA agonist.
- GC37784 THIP THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors (eGABARs) agonist (with blood-brain barrier permeability), shows an EC50 value of 13 ?M for δ-GABAAR.
- GC10856 THIP hydrochloride THIP hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM).
- GC38215 Tiagabine
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GC17402
Tiagabine hydrochloride
GABA uptake inhibitor
- GC37788 Tiagabine hydrochloride hydrate Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively.
- GC16360 TP 003 GABAA receptor (α3 subtype) partial agonist
- GC30865 TPA 023 TPA 023 is a GABAA α2/α3 subtype-selective agonist, with Ki of 0.19-0.41 nM.
- GC67996 TPA-023B
- GC10183 TPMPA GABAA-ρ antagonist
- GC10262 Tracazolate hydrochloride GABAA receptor modulator
- GC17381 trans-4-Hydroxycrotonic acid ligand of γ-hydroxybutyric acid (GHB) receptor
- GC14933 U 89843A Positive allosteric modulator of GABAA receptors
- GC13509 U 90042 GABAA receptor ligand
- GC11013 U 93631 GABAA receptor antagonist
- GC31013 U-101017 (PNU 101017) U-101017 (PNU 101017) is a partial agonist of benzodiazepine receptor and GABAA receptor, with anxiolytic effects.
- GC11600 Valerenic acid Positive allosteric modulator of GABAA receptor
- GC41613 Valnoctamide Valnoctamide is an isomer of the valproic acid amide, valpromide.
- GC37905 Vigabatrin Inhibitor of GABA transaminase
- GC13387 Vigabatrin Hydrochloride GABA transaminase inhibitor
- GC10313 ZAPA sulfate GABAA receptors agonist
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GC13922
ZK 93423 hydrochloride
GABAA receptor agonist
- GC16010 ZK 93426 hydrochloride benzodiazepine receptor antagonist,competitive