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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> GlyT

GlyT

GlyT1 (glycine transporter, SLC6A9) is a member of Na+ and Cl(-)- dependent neurotransmitter transporter proteins. It regulates the glycine concentration in NMDA receptor-mediate neurotransmission.

Products for  GlyT

  1. Cat.No. Product Name Information
  2. GC15467 ALX 5407 hydrochloride GlyT1 inhibitor,selective non-transportable ALX 5407 hydrochloride Chemical Structure
  3. GC70319 ALX-1393 TFA ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model. ALX-1393 TFA Chemical Structure
  4. GC38888 ASP2535 ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor. ASP2535 Chemical Structure
  5. GC10206 Bitopertin

    RG-1678, RO-4917838

     An inhibitor of GlyT1 Bitopertin Chemical Structure
  6. GC35527 Bitopertin R enantiomer Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin R enantiomer Chemical Structure
  7. GC65319 GlyT1 Inhibitor 1 GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. GlyT1 Inhibitor 1 Chemical Structure
  8. GC63014 Iclepertin

    BI-425809

     Iclepertin (BI-425809) is a potent, selective and orally active glycine transporter 1 (GlyT1) inhibitor. Iclepertin Chemical Structure
  9. GC11341 LY 2365109 hydrochloride glycine transporter 1 (GlyT1) inhibitor LY 2365109 hydrochloride Chemical Structure
  10. GC12032 NFPS

    (Rac)-NFPS

     NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively. NFPS Chemical Structure
  11. GC64690 Opiranserin hydrochloride

    VVZ-149 hydrochloride

     Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride Chemical Structure
  12. GC50059 Org 24598 Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo Org 24598 Chemical Structure
  13. GC16402 Org 24598 lithium salt glial glycine transporter (GlyT1) inhibitor Org 24598 lithium salt Chemical Structure
  14. GC12436 Org 25543 hydrochloride GlyT2 inhibitor Org 25543 hydrochloride Chemical Structure
  15. GC60284 PF-03463275 PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM. PF-03463275 Chemical Structure
  16. GC11195 Sarcosine Endogenous inhibitor of GlyT1 Sarcosine Chemical Structure
  17. GC67871 SSR504734 SSR504734 Chemical Structure
  18. GC44951 Stearoyl-L-carnitine (chloride)

    C18 Carnitine

    Stearoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.

     Stearoyl-L-carnitine (chloride) Chemical Structure
  19. GC31115 Tilapertin (AMG747)

    AMG747

     Tilapertin (AMG747) is an oral inhibitor of glycine transporter type-1 (GlyT1). Tilapertin (AMG747) Chemical Structure

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