NKCC
NKCC (Na-K-Cl cotransporter) is an electrically silent membrane-bound channels that mediates Na and Cl reabsorption. It functions in regulating cell volume and ionic balance.
Products for NKCC
- Cat.No. Product Name Information
- GC38738 Azosemide Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246??M and 0.197??M for hNKCC1A and NKCC1B, respectively.
- GC15524 Bumetanide NKCC cotransporter inhibitor
- GC16795 DCA DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor.
- GC12970 Furosemide GABAA receptors antagonist
- GC36091 Furosemide sodium A loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter