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Home >> Signaling Pathways >> MAPK Signaling >> MNK

MNK

MNK (MAP kinase-interacting kinases) is a group of serine/threonine kinase that phosphorylates eukaryotic initiation factor 4E (eIF4E) in the MAPK signaling pathways. It plays an important role in cell transformation and tumor progression.

Products for  MNK

  1. Cat.No. Product Name Information
  2. GC10666 CGP 57380 MNK1 inhibitor, specific and selective CGP 57380 Chemical Structure
  3. GC33033 ETC-206 ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively. ETC-206 Chemical Structure
  4. GC32937 SLV-2436 (SEL201-88) SLV-2436 (SEL201-88) is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 nM and 5.4 nM, respectively. SLV-2436 (SEL201-88) Chemical Structure
  5. GC19131 Tomivosertib eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. Tomivosertib Chemical Structure

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