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PKA

PKA (protein kinase A), also known as cAMP-dependent protein kinase, has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

Products for  PKA

  1. Cat.No. Product Name Information
  2. GC16929 8-Bromo-cAMP, sodium salt Cell-permeable cAMP analog that activates PKA 8-Bromo-cAMP, sodium salt  Chemical Structure
  3. GC64460 8-Chloro-cAMP 8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity. 8-Chloro-cAMP  Chemical Structure
  4. GC15352 8-CPT-Cyclic AMP (sodium salt) 8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP (sodium salt)  Chemical Structure
  5. GC60037 A-3 hydrochloride A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride  Chemical Structure
  6. GC17712 AT13148 Multi-AGC kinase inhibitor,ATP-competitive AT13148  Chemical Structure
  7. GC12297 AT7867

    Akt1/2/3 and p70S6K/PKA inhibitor

    AT7867  Chemical Structure
  8. GC10918 AT7867 dihydrochloride A potent and orally bioavailable pan-Akt inhibitor AT7867 dihydrochloride  Chemical Structure
  9. GC35518 Bilobetin A biflavonoid with diverse biological activities Bilobetin  Chemical Structure
  10. GC35565 Bucladesine calcium salt Bucladesine calcium salt salt (Dibutyryl-cAMP calcium salt;DC2797 calcium salt) is a cell-permeable cyclic AMP (cAMP) analog and selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine calcium salt  Chemical Structure
  11. GC11605 C-1 C-1 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. C-1 also used as a ROCK inhibitor. C-1  Chemical Structure
  12. GC10941 cAMPS-Rp, triethylammonium salt cAMPS-Rp, triethylammonium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. cAMPS-Rp, triethylammonium salt  Chemical Structure
  13. GC19090 CCG215022 CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 uM, 0.38±0.06 uM and 3.9±1 uM for GRK2, GRK5 and GRK1, respectively. CCG215022  Chemical Structure
  14. GC15525 cGMP Dependent Kinase Inhibitor Peptide cGMP Dependent Kinase Inhibitor Peptide is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM. cGMP Dependent Kinase Inhibitor Peptide  Chemical Structure
  15. GC31525 CREBtide A PKA substrate CREBtide  Chemical Structure
  16. GC50181 CW 008 PKA signaling activator; promotes osteogenesis from hMSCs CW 008  Chemical Structure
  17. GN10336 Daphnetin Daphnetin  Chemical Structure
  18. GC12824 Dibutyryl-cAMP, sodium salt Dibutyryl-cAMP, sodium salt salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Dibutyryl-cAMP, sodium salt  Chemical Structure
  19. GC13869 Fasudil Calcium antagonist Fasudil  Chemical Structure
  20. GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator. Fasudil (HA-1077) HCl  Chemical Structure
  21. GC17255 Gliotoxin An immunosuppressive mycotoxin with diverse biological effects Gliotoxin  Chemical Structure
  22. GC19396 H 89

    A potent inhibitor of cyclic AMP-dependent protein kinase

    H 89  Chemical Structure
  23. GC10074 H 89 2HCl H 89 2HCl is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase. H 89 2HCl  Chemical Structure
  24. GC12799 H-8 (hydrochloride) H-8 (dihydrochloride) is a cell-permeable, reversible and ATP-competitive PKA inhibitor. H-8 (hydrochloride)  Chemical Structure
  25. GC65303 Jaspamycin Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin  Chemical Structure
  26. GC11362 K 252a A protein kinase inhibitor K 252a  Chemical Structure
  27. GC13640 Kemptide substrate for cAMP-dependent protein kinase (PKA) Kemptide  Chemical Structure
  28. GC36391 Kemptide Phospho-Ser5 Kemptide (Phospho-Ser5) is a phosphate acceptor peptide that serves as a specific substrate for cAMP-dependent protein kinase (PKA). Kemptide Phospho-Ser5  Chemical Structure
  29. GC14648 KT 5720

    protein kinase A inhibitor, potent and selective

    KT 5720  Chemical Structure
  30. GC17346 KT 5823 A protein kinase G inhibitor KT 5823  Chemical Structure
  31. GC30545 Malantide Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts. Malantide is also an efficient substrate for PKC with a Km of 16 μM. Malantide  Chemical Structure
  32. GC33771 Metadoxine Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway. Metadoxine  Chemical Structure
  33. GC49440 ML-9 A PKB/Akt inhibitor ML-9  Chemical Structure
  34. GC44653 PKA Inhibitor (5-24) PKA Inhibitor (5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. PKA Inhibitor (5-24)  Chemical Structure
  35. GP10075 PKA inhibitor fragment (6-22) amide

    A synthetic peptide inhibitor of PKA

    PKA inhibitor fragment (6-22) amide  Chemical Structure
  36. GC61512 PKA Inhibitor Fragment (6-22) amide TFA PKA Inhibitor Fragment (6-22) amide TFA is an inhibitor of cAMP-dependent protein kinase A (PKA), with a Ki of 2.8 nM. PKA Inhibitor Fragment (6-22) amide TFA  Chemical Structure
  37. GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor PKI (14-22) amide (myristoylated) (trifluoroacetate salt)  Chemical Structure
  38. GC69715 PKI (14-24)amide TFA

    PKI (14-24)amide TFA is an effective inhibitor of PKA. In cell cytosol, PKI (14-24)amide strongly inhibits the activity of cyclic AMP-dependent protein kinase.

    PKI (14-24)amide TFA  Chemical Structure
  39. GC12321 PKI 14-22 amide, myristoylated PKA inhibitor PKI 14-22 amide, myristoylated  Chemical Structure
  40. GC61849 PKI 14-22 amide,myristoylated TFA PKI 14-22 amide,myristoylated TFA is a potent cAMP-dependent PKA inhibitor. PKI 14-22 amide,myristoylated TFA reduces the IgG-mediated phagocytic response and also inhibits neutrophil adhesion. PKI 14-22 amide,myristoylated TFA  Chemical Structure
  41. GC50502 RI-STAD 2 AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable RI-STAD 2  Chemical Structure
  42. GC44853 Rp-8-CPT-Cyclic AMP (sodium salt) Rp-8-CPT-Cyclic AMP (sodium salt), a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-Cyclic AMP (sodium salt)  Chemical Structure
  43. GC63176 Rp-cAMPS sodium salt Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 ?M and 4.5 ?M, respectively) antagonist. Rp-cAMPS sodium salt  Chemical Structure
  44. GC10428 Sp-5,6-dichloro-cBIMPS (sodium salt) PKA activator Sp-5,6-dichloro-cBIMPS (sodium salt)  Chemical Structure
  45. GC61747 Sp-cAMPS Sp-cAMPS, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS  Chemical Structure
  46. GC50406 st-Ht31 Inhibits PKA/AKAP interactions; cell permeable st-Ht31  Chemical Structure
  47. GC50407 st-Ht31 P Negative control for st-Ht31 st-Ht31 P  Chemical Structure
  48. GC50501 STAD 2 AKAP disruptor; selectively binds PKA-RII and blocks its interaction with AKAP; cell permeable STAD 2  Chemical Structure
  49. GC15299 Staurosporine(CGP 41251)

    A potent inhibitor of protein kinase C

    Staurosporine(CGP 41251)  Chemical Structure
  50. GC16678 UCN-02 protein kinase C inhibitor UCN-02  Chemical Structure
  51. GC30857 Warangalone (Scandenolone) Warangalone (Scandenolone) is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone (Scandenolone)  Chemical Structure

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