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Home >> Signaling Pathways >> Metabolism >> Dopamine β-hydroxylase

Dopamine β-hydroxylase

DBH (Dopamine-β-hydroxylase) is a copper-containing monooxygenase that catalyzes the biosynthesis of catecholamine neurotransmitter, norepinephrine from dopamine. Deficiency in DBH causes orthostatic hypotension, autonomic disorders etc.

Products for  Dopamine β-hydroxylase

  1. Cat.No. Product Name Information
  2. GC60519 4-Hydroxyderricin 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin Chemical Structure
  3. GC10801 Disulfiram An irreversible inhibitor of aldehyde dehydrogenase Disulfiram Chemical Structure
  4. GC32575 Etamicastat (BIA 5-453) Etamicastat (BIA 5-453) (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM. Etamicastat (BIA 5-453) Chemical Structure
  5. GC18061 Fusaric Acid

    Fusaric acid, as a mycotoxin produced by the Fusarium species, has diverse toxicological effects in plants and animals.

     Fusaric Acid Chemical Structure
  6. GC15382 Isotretinoin A retinoid Isotretinoin Chemical Structure
  7. GC15558 Mildronate An inhibitor of carnitine biosynthesis Mildronate Chemical Structure
  8. GC36722 Nepicastat Nepicastat (SYN117) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat Chemical Structure
  9. GC12596 Nepicastat (SYN-117) HCl An inhibitor of dopamine β-hydroxylase Nepicastat (SYN-117) HCl Chemical Structure
  10. GC10718 PF 915275 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor PF 915275 Chemical Structure
  11. GC32593 Zamicastat (BIA 5-1058) Zamicastat (BIA 5-1058) (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat (BIA 5-1058) Chemical Structure

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