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Home >> Signaling Pathways >> Metabolism >> PDE

PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Products for  PDE

  1. Cat.No. Product Name Information
  2. GC13495 Trequinsin hydrochloride

    PDE3 inhibitor

     Trequinsin hydrochloride Chemical Structure
  3. GC31668 TYK2-IN-2 TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TYK2-IN-2 Chemical Structure
  4. GC13287 Udenafil PDE5 inhibitor Udenafil Chemical Structure
  5. GC15242 Vardenafil PDE5 inhibitor Vardenafil Chemical Structure
  6. GC10588 Vardenafil HCl Trihydrate An inhibitor of PDE5 and PDE6 Vardenafil HCl Trihydrate Chemical Structure
  7. GC37888 Vardenafil hydrochloride Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride Chemical Structure
  8. GC32110 Vesnarinone (OPC-8212) Vesnarinone (OPC-8212) (OPC-8212) is an orally active phosphodiesterase 3 (PDE3) inhibitor. Vesnarinone (OPC-8212) Chemical Structure
  9. GC16658 Vinpocetine PDE inhibitor Vinpocetine Chemical Structure
  10. GC37923 VP3.15 VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 Chemical Structure
  11. GC37924 VP3.15 dihydrobromide VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide Chemical Structure
  12. GC31814 WAY127093B racemate WAY127093B racemate is the racemate of WAY127093B. WAY127093B racemate Chemical Structure
  13. GC31327 Win 58237 Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity. Win 58237 Chemical Structure
  14. GC32659 Win-62005 Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively. Win-62005 Chemical Structure
  15. GC12059 YM 976 PDE4 inhibitor, orally active YM 976 Chemical Structure
  16. GC12909 Zaprinast phosphodiesterase inhibitor and GPR35 agonist Zaprinast Chemical Structure
  17. GC16426 Zardaverine A dual inhibitor of PDE3 and PDE4 Zardaverine Chemical Structure

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